Best TWAS P=5.02e-09 · Best GWAS P=1.52e-08 conditioned to 1.3e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Liver | ATXN7L2 | 0.39 | 0.04 | lasso | 12 | 0.21 | 1.3e-06 | 4.4 | 5.8 | 5.0e-09 | 0.07 | 0.25 | 0.26 | TRUE |
2 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CELSR2 | 0.08 | 0.00 | blup | 62 | 0.02 | 8.1e-03 | 3.7 | 5.2 | 1.8e-07 | 0.01 | 0.00 | 0.19 | FALSE |
3 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SORT1 | 0.04 | 0.01 | blup | 60 | 0.03 | 4.4e-03 | 5.0 | 5.2 | 1.7e-07 | 0.06 | 0.01 | 0.58 | FALSE |