Best TWAS P=3.85e-48 · Best GWAS P=1.18e-87 conditioned to 3.48e-28
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TRPS1 | 0.05 | 0.02 | enet | 19 | 0.02 | 2.4e-03 | 6.0 | -5.9 | 3.7e-09 | -0.12 | 0.38 | 0.13 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | EIF3H | 0.10 | 0.08 | lasso | 5 | 0.08 | 3.7e-10 | 5.3 | -5.8 | 5.2e-09 | -0.04 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TRPS1 | 0.04 | 0.03 | blup | 102 | 0.01 | 9.6e-03 | 4.0 | 6.8 | 9.8e-12 | 0.51 | 0.07 | 0.09 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | TRPS1 | 0.09 | 0.03 | blup | 102 | 0.03 | 5.2e-04 | 16.9 | -14.6 | 3.8e-48 | -0.69 | 0.03 | 0.71 | TRUE |