Best TWAS P=2.62e-13 · Best GWAS P=5.82e-25 conditioned to 2.55e-33
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DEPTOR | 0.15 | 0.03 | blup | 505 | 0.09 | 8.2e-11 | -3.7 | -5.3 | 1.4e-07 | -0.04 | 0.01 | 0.99 | FALSE |
| 2 | NTR | Blood | NOV | 0.02 | 0.01 | bslmm | 481 | 0.01 | 1.7e-04 | -1.9 | -5.2 | 1.6e-07 | 0.10 | 0.83 | 0.01 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | MAL2 | 0.05 | 0.00 | blup | 503 | 0.00 | 7.4e-02 | -3.7 | -6.7 | 2.1e-11 | -0.16 | 0.14 | 0.02 | TRUE |
| 4 | YFS | Blood | ENPP2 | 0.03 | 0.02 | enet | 8 | 0.03 | 7.6e-09 | 3.1 | 5.5 | 3.8e-08 | 0.05 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Glioblastoma Multiforme | DSCC1 | 0.17 | 0.08 | blup | 54 | 0.06 | 5.9e-03 | 4.7 | 5.3 | 9.7e-08 | 0.00 | 0.01 | 0.43 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | TNFRSF11B | 0.05 | 0.05 | lasso | 3 | 0.04 | 1.4e-05 | 7.6 | 7.3 | 2.6e-13 | -0.23 | 0.41 | 0.56 | TRUE |