Best TWAS P=7.2e-10 · Best GWAS P=2.34e-07 conditioned to 0.133
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | GS1-393G12.12 | 0.09 | 0.05 | lasso | 4 | 0.03 | 9.8e-03 | 4.9 | 5.2 | 2.1e-07 | 0.83 | 0.01 | 0.70 | TRUE |
| 2 | YFS | Blood | VPS28 | 0.43 | 0.30 | enet | 40 | 0.46 | 7.6e-172 | -4.7 | 5.4 | 5.7e-08 | 0.23 | 0.02 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | VPS28 | 0.08 | 0.04 | blup | 24 | 0.03 | 1.5e-02 | -4.9 | 5.3 | 1.2e-07 | 0.19 | 0.00 | 0.60 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | NFKBIL2 | 0.05 | 0.00 | blup | 21 | 0.03 | 4.8e-04 | -4.7 | 6.2 | 7.2e-10 | 0.22 | 0.01 | 0.92 | TRUE |