Best TWAS P=8.09e-09 · Best GWAS P=8.05e-08 conditioned to 0.846
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | LY6E | 0.47 | 0.15 | lasso | 9 | 0.11 | 4.7e-04 | 5.1 | -5.3 | 1.3e-07 | -0.95 | 0.01 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | LOC100133669 | 0.22 | 0.19 | lasso | 13 | 0.18 | 6.8e-11 | 5.1 | 5.5 | 3.8e-08 | 0.98 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | LOC100133669 | 0.06 | 0.10 | lasso | 6 | 0.10 | 2.5e-11 | 5.1 | 5.2 | 2.4e-07 | 0.98 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOC100133669 | 0.15 | 0.20 | lasso | 1 | 0.19 | 9.0e-20 | 5.1 | 5.1 | 2.9e-07 | 0.98 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LOC100133669 | 0.06 | 0.07 | lasso | 3 | 0.07 | 9.8e-06 | 5.1 | 5.1 | 3.1e-07 | 0.91 | 0.00 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LOC100133669 | 0.39 | 0.39 | enet | 13 | 0.40 | 2.4e-15 | 5.1 | 5.8 | 8.1e-09 | 0.94 | 0.00 | 1.00 | TRUE |