Best TWAS P=1.43e-12 · Best GWAS P=1.36e-34 conditioned to 1.71e-34
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | IKBKAP | 0.09 | 0.00 | enet | 24 | 0.01 | 9.9e-02 | 3.8 | -7.1 | 1.4e-12 | 0.00 | 0.11 | 0.26 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | IKBKAP | 0.15 | 0.02 | enet | 15 | 0.05 | 3.5e-03 | -3.8 | -5.6 | 2.4e-08 | 0.07 | 0.14 | 0.04 | FALSE |
| 3 | METSIM | Adipose | IKBKAP | 0.08 | 0.01 | blup | 648 | 0.03 | 1.7e-05 | -3.8 | -5.8 | 6.3e-09 | 0.06 | 0.82 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | IKBKAP | 0.10 | 0.05 | enet | 17 | 0.05 | 5.4e-06 | 4.2 | -6.0 | 2.2e-09 | 0.04 | 0.79 | 0.12 | FALSE |