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chr9:94,394,640-98,975,128

Best TWAS P=2.4e-52 · Best GWAS P=6.14e-52 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ANKRD19P	0.07	0.06	lasso	7	0.04	3.3e-06	-8.98	9.0	2.8e-19	0.00	0.03	0.97	TRUE
2	CommonMind	Brain Pre-frontal Cortex	BICD2	0.06	0.04	blup	424	0.04	6.9e-06	5.54	7.2	7.1e-13	-0.01	0.96	0.01	FALSE
3	CommonMind	Brain Pre-frontal Cortex	ZNF484	0.41	0.35	lasso	9	0.36	2.8e-45	-8.59	8.0	1.1e-15	0.02	0.93	0.07	FALSE
4	GTEx	Adipose Subcutaneous	SUSD3	0.15	0.02	enet	19	0.07	1.0e-06	2.76	5.5	4.5e-08	0.00	0.10	0.78	FALSE
5	GTEx	Adipose Subcutaneous	ANKRD19P	0.06	0.03	enet	16	0.04	2.2e-04	-8.98	8.1	6.2e-16	0.02	0.05	0.94	FALSE
6	GTEx	Artery Tibial	PTPDC1	0.06	0.00	enet	22	0.00	6.5e-01	-1.46	-7.8	7.3e-15	0.05	0.08	0.21	FALSE
7	GTEx	Artery Tibial	RP11-435O5.5	0.09	0.04	lasso	2	0.02	7.3e-03	-15.12	14.9	1.8e-50	-0.98	0.01	0.97	FALSE
8	GTEx	Brain Caudate basal ganglia	OGN	0.15	-0.01	enet	18	0.02	7.7e-02	-2.76	-5.2	1.6e-07	0.00	0.09	0.18	FALSE
9	GTEx	Brain Caudate basal ganglia	PHF2	0.42	0.00	enet	33	0.04	2.4e-02	0.68	8.9	6.7e-19	0.03	0.08	0.24	TRUE
10	GTEx	Brain Cerebellar Hemisphere	BICD2	0.27	0.06	lasso	9	0.04	3.9e-02	4.55	5.2	2.4e-07	0.05	0.12	0.09	FALSE
11	GTEx	Brain Cerebellar Hemisphere	RP11-165J3.6	0.38	0.10	enet	15	0.21	3.3e-06	-2.63	-5.2	1.6e-07	0.00	0.30	0.06	FALSE
12	GTEx	Brain Cerebellum	ZNF484	0.21	0.01	lasso	9	0.01	1.7e-01	5.76	6.6	3.4e-11	0.04	0.10	0.11	FALSE
13	GTEx	Brain Cerebellum	BICD2	0.23	0.06	enet	21	0.17	8.5e-06	5.76	7.4	1.1e-13	0.12	0.07	0.34	FALSE
14	GTEx	Brain Hypothalamus	RP11-2B6.3	0.33	-0.01	enet	40	0.07	8.3e-03	10.93	11.0	3.9e-28	-0.06	0.06	0.35	FALSE
15	GTEx	Brain Nucleus accumbens basal ganglia	BICD2	0.13	0.20	lasso	2	0.16	3.8e-05	6.75	6.8	9.5e-12	0.00	0.12	0.33	FALSE
16	GTEx	Breast Mammary Tissue	FBP1	0.08	0.00	enet	4	0.03	9.7e-03	7.89	7.8	5.3e-15	-0.06	0.31	0.14	FALSE
17	GTEx	Cells Transformed fibroblasts	PTPDC1	0.14	0.11	lasso	5	0.11	1.7e-08	-6.56	-6.6	3.6e-11	0.04	1.00	0.00	TRUE
18	GTEx	Cells Transformed fibroblasts	PHF2	0.07	0.06	lasso	5	0.04	5.5e-04	11.68	11.3	9.1e-30	0.04	0.14	0.80	FALSE
19	GTEx	Cells Transformed fibroblasts	RP11-307E17.8	0.24	0.05	enet	28	0.13	6.7e-10	-3.81	7.1	1.6e-12	-0.05	0.97	0.00	FALSE
20	GTEx	Cells Transformed fibroblasts	RP11-435O5.5	0.14	0.04	lasso	4	0.02	7.9e-03	-13.97	13.9	1.2e-43	-0.61	0.35	0.06	FALSE
21	GTEx	Colon Sigmoid	RP11-307E17.8	0.23	0.19	enet	12	0.19	2.8e-07	-3.94	5.3	1.2e-07	0.00	0.80	0.01	TRUE
22	GTEx	Esophagus Gastroesophageal Junction	ANKRD19P	0.28	0.03	lasso	5	0.05	7.3e-03	-9.63	6.0	2.1e-09	-0.10	0.01	0.88	TRUE
23	GTEx	Esophagus Mucosa	FGD3	0.11	0.03	enet	15	0.09	2.3e-06	-8.09	7.5	4.8e-14	0.03	0.11	0.84	FALSE
24	GTEx	Esophagus Mucosa	CENPP	0.09	0.01	lasso	5	0.02	2.1e-02	4.54	-6.4	1.3e-10	-0.06	0.40	0.19	FALSE
25	GTEx	Esophagus Muscularis	PTPDC1	0.15	0.00	lasso	4	0.03	6.1e-03	9.73	-11.9	1.9e-32	0.00	0.37	0.02	FALSE
26	GTEx	Esophagus Muscularis	RP11-307E17.8	0.32	0.26	enet	28	0.28	3.8e-17	-3.94	7.2	6.4e-13	-0.04	1.00	0.00	FALSE
27	GTEx	Heart Atrial Appendage	FAM120AOS	0.10	0.04	lasso	3	0.04	5.1e-03	-7.96	-7.9	3.3e-15	0.00	0.27	0.04	FALSE
28	GTEx	Heart Atrial Appendage	RP11-307E17.8	0.15	0.10	lasso	4	0.06	1.5e-03	-7.36	6.4	1.9e-10	-0.02	0.45	0.03	FALSE
29	GTEx	Heart Atrial Appendage	RP11-435O5.4	0.18	0.00	lasso	5	0.00	6.2e-01	-5.16	7.6	2.2e-14	-0.09	0.05	0.38	TRUE
30	GTEx	Muscle Skeletal	RP11-165J3.6	0.17	0.10	enet	17	0.10	4.0e-10	-2.25	-6.5	5.6e-11	-0.02	1.00	0.00	TRUE
31	GTEx	Nerve Tibial	ZNF484	0.28	0.06	enet	28	0.13	3.1e-09	7.58	7.8	8.3e-15	-0.07	0.28	0.67	FALSE
32	GTEx	Nerve Tibial	ANKRD19P	0.15	0.07	lasso	3	0.08	3.3e-06	-5.72	7.0	1.9e-12	0.02	0.02	0.97	FALSE
33	GTEx	Pituitary	FANCC	0.17	0.02	lasso	7	0.02	9.9e-02	5.29	-6.8	1.2e-11	0.08	0.12	0.06	FALSE
34	GTEx	Prostate	FAM120A	0.24	0.19	lasso	3	0.13	4.1e-04	-6.66	-6.4	1.2e-10	0.03	0.07	0.55	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	FGD3	0.25	0.10	lasso	7	0.17	9.6e-10	-4.92	7.2	5.6e-13	-0.01	0.55	0.42	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	CENPP	0.23	0.09	lasso	11	0.07	9.6e-05	5.34	-7.4	1.8e-13	-0.05	0.09	0.89	FALSE
37	GTEx	Skin Sun Exposed Lower leg	FAM120A	0.11	0.00	enet	45	0.01	6.9e-02	-8.22	5.3	9.2e-08	0.05	0.08	0.04	TRUE
38	GTEx	Skin Sun Exposed Lower leg	IPPK	0.17	0.07	enet	8	0.07	2.7e-06	6.34	-5.7	1.5e-08	-0.02	0.97	0.00	FALSE
39	GTEx	Skin Sun Exposed Lower leg	FGD3	0.23	0.11	enet	14	0.20	1.5e-16	-4.92	7.6	3.5e-14	-0.01	0.80	0.19	FALSE
40	GTEx	Skin Sun Exposed Lower leg	PTPDC1	0.07	0.00	lasso	4	0.00	8.9e-01	-7.09	7.4	1.8e-13	0.09	0.33	0.04	FALSE
41	GTEx	Stomach	RP11-165J3.6	0.57	0.23	enet	35	0.27	1.9e-13	-2.25	-5.6	2.1e-08	0.01	1.00	0.00	FALSE
42	GTEx	Thyroid	ZNF169	0.09	0.03	lasso	4	0.05	1.9e-04	8.73	-6.4	1.9e-10	0.10	0.85	0.01	FALSE
43	GTEx	Uterus	PTPDC1	0.40	0.19	lasso	8	0.07	1.7e-02	-6.30	-5.7	1.2e-08	0.03	0.09	0.05	TRUE
44	GTEx	Whole Blood	RP11-165J3.6	0.10	0.07	lasso	4	0.05	1.1e-05	-6.97	-9.4	6.0e-21	-0.01	0.43	0.52	FALSE
45	METSIM	Adipose	RP11-307E17.8	0.11	0.09	lasso	8	0.11	1.4e-15	-4.35	7.1	1.7e-12	-0.02	1.00	0.00	TRUE
46	NTR	Blood	ANKRD19	0.01	0.01	enet	11	0.01	6.6e-03	-8.98	8.1	4.3e-16	0.02	0.02	0.97	FALSE
47	NTR	Blood	ZNF169	0.02	0.00	lasso	6	0.00	1.1e-02	11.04	12.3	7.2e-35	-0.02	0.09	0.04	TRUE
48	NTR	Blood	ZNF484	0.03	0.01	bslmm	433	0.01	1.3e-04	-9.34	8.8	1.5e-18	-0.03	0.01	0.97	FALSE
49	The Cancer Genome Atlas	Breast Invasive Carcinoma	BARX1	0.04	0.00	blup	66	0.01	6.3e-04	9.51	-11.7	1.4e-31	0.00	0.01	0.84	TRUE
50	The Cancer Genome Atlas	Breast Invasive Carcinoma	PHF2	0.02	0.01	blup	104	0.01	4.6e-03	11.84	10.5	1.1e-25	0.03	0.11	0.37	FALSE
51	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IPPK	0.06	0.03	blup	49	0.04	5.8e-03	6.79	-5.7	1.0e-08	-0.01	0.01	0.74	FALSE
52	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPP	0.21	0.04	enet	16	0.10	1.9e-06	5.34	-6.1	1.1e-09	-0.09	0.01	0.96	FALSE
53	The Cancer Genome Atlas	Esophageal Carcinoma	PHF2	0.29	0.14	blup	103	0.16	1.0e-05	13.75	11.4	3.5e-30	0.03	0.00	0.99	TRUE
54	The Cancer Genome Atlas	Esophageal Carcinoma	PTPDC1	0.16	0.08	lasso	4	0.07	2.9e-03	-6.56	-6.6	3.4e-11	0.03	0.08	0.05	TRUE
55	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPP	0.06	0.02	blup	160	0.04	6.3e-05	5.34	-5.3	1.1e-07	-0.07	0.05	0.90	FALSE
56	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HIATL1	0.04	0.03	blup	44	0.03	3.6e-04	-3.94	5.3	1.3e-07	-0.02	0.22	0.04	TRUE
57	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FAM22F	0.03	0.02	blup	26	0.01	2.8e-02	9.10	7.8	4.6e-15	-0.08	0.00	0.94	FALSE
58	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PTCH1	0.04	0.00	blup	56	0.02	1.6e-03	-3.69	5.8	6.1e-09	-0.13	0.03	0.04	FALSE
59	The Cancer Genome Atlas	Brain Lower Grade Glioma	ANKRD19	0.04	0.03	blup	70	0.02	2.0e-03	-8.58	8.2	3.4e-16	0.01	0.03	0.95	FALSE
60	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF169	0.06	0.00	enet	11	0.04	3.1e-05	8.61	7.2	4.4e-13	-0.04	0.01	0.91	FALSE
61	The Cancer Genome Atlas	Lung Adenocarcinoma	ECM2	0.10	0.04	lasso	2	0.04	4.2e-05	6.11	6.0	2.3e-09	0.02	0.00	0.99	TRUE
62	The Cancer Genome Atlas	Lung Adenocarcinoma	PHF2	0.07	0.03	blup	104	0.05	1.9e-06	13.75	10.5	7.8e-26	0.03	0.00	1.00	TRUE
63	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IPPK	0.03	0.02	blup	51	0.01	3.2e-02	6.11	-5.5	3.0e-08	-0.03	0.02	0.75	TRUE
64	The Cancer Genome Atlas	Prostate Adenocarcinoma	PTCH1	0.02	0.01	blup	54	0.02	1.1e-03	-14.45	15.2	2.4e-52	-0.87	0.03	0.57	TRUE
65	The Cancer Genome Atlas	Stomach Adenocarcinoma	ANKRD19	0.04	0.01	blup	70	0.02	6.2e-03	-5.56	8.6	5.8e-18	0.04	0.01	0.93	FALSE
66	The Cancer Genome Atlas	Thyroid Carcinoma	FBP1	0.05	0.00	blup	80	0.01	1.8e-02	5.47	5.2	2.4e-07	-0.07	0.02	0.55	TRUE
67	The Cancer Genome Atlas	Thyroid Carcinoma	IPPK	0.03	0.04	blup	50	0.04	6.7e-05	6.75	-6.7	2.5e-11	-0.04	0.01	0.98	FALSE
68	The Cancer Genome Atlas	Thyroid Carcinoma	PHF2	0.07	0.00	blup	104	0.01	8.4e-02	5.65	5.4	6.9e-08	0.00	0.03	0.05	FALSE