[Hub]/) : Traits : Heel T-Score : ← →

chr9:125,444,045-127,872,298

Best TWAS P=2.13e-12 · Best GWAS P=1.29e-13 conditioned to 1.95e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DENND1A 0.06 0.02 blup 613 0.04 2.6e-05 -2.9 -6.6 3.9e-11 0.65 0.06 0.93 TRUE
2 GTEx Adipose Subcutaneous PSMB7 0.08 0.04 lasso 6 0.04 3.4e-04 5.5 -6.2 7.8e-10 -0.02 0.42 0.52 FALSE
3 GTEx Artery Aorta PSMB7 0.15 0.03 enet 16 0.05 1.4e-03 -5.6 -5.2 2.0e-07 -0.05 0.16 0.26 FALSE
4 GTEx Artery Tibial PSMB7 0.07 0.04 enet 7 0.03 4.1e-03 5.5 -5.3 8.9e-08 -0.03 0.11 0.81 FALSE
5 GTEx Breast Mammary Tissue PSMB7 0.11 0.03 lasso 7 0.04 4.7e-03 5.7 -5.8 6.6e-09 -0.03 0.20 0.29 FALSE
6 GTEx Cells Transformed fibroblasts PSMB7 0.09 0.07 enet 11 0.06 2.1e-05 -5.6 -5.3 1.1e-07 -0.03 0.82 0.13 FALSE
7 GTEx Colon Sigmoid PSMB7 0.15 0.10 lasso 3 0.09 3.3e-04 6.3 -6.3 2.8e-10 -0.05 0.06 0.87 FALSE
8 GTEx Thyroid NEK6 0.20 0.21 lasso 4 0.20 1.3e-15 6.9 -7.0 2.1e-12 -0.02 0.15 0.85 TRUE
9 GTEx Thyroid PSMB7 0.06 0.04 lasso 2 0.06 4.1e-05 4.8 -5.7 1.4e-08 -0.02 0.02 0.97 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma NEK6 0.04 0.02 blup 87 0.02 2.5e-05 -5.7 -5.4 6.8e-08 -0.03 0.43 0.53 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma NEK6 0.06 0.01 blup 87 0.04 1.0e-04 -5.7 -6.4 1.7e-10 -0.05 0.01 0.97 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB7 0.03 0.04 lasso 4 0.04 1.2e-04 6.1 -6.2 7.4e-10 -0.07 0.03 0.94 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma PSMB7 0.06 0.06 lasso 4 0.04 3.7e-05 5.3 -5.3 9.3e-08 -0.04 0.30 0.70 FALSE