Best TWAS P=7.8e-10 · Best GWAS P=2.98e-13 conditioned to 1.85e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-517P14.2 | 0.14 | 0.09 | enet | 14 | 0.07 | 4.4e-06 | 4.6 | 6.2 | 7.8e-10 | 0.16 | 0.98 | 0.00 | TRUE |
| 2 | GTEx | Artery Tibial | RP11-517P14.2 | 0.18 | 0.08 | lasso | 5 | 0.10 | 2.2e-08 | 5.3 | 5.2 | 2.5e-07 | 0.00 | 0.98 | 0.00 | FALSE |
| 3 | GTEx | Colon Transverse | RP11-517P14.2 | 0.19 | 0.18 | lasso | 3 | 0.19 | 3.3e-09 | 5.3 | 6.0 | 2.6e-09 | 0.03 | 0.95 | 0.00 | FALSE |
| 4 | GTEx | Esophagus Mucosa | RP11-517P14.2 | 0.15 | 0.08 | lasso | 4 | 0.05 | 4.9e-04 | 5.3 | 5.5 | 2.8e-08 | 0.02 | 0.87 | 0.01 | FALSE |
| 5 | GTEx | Lung | RP11-517P14.2 | 0.14 | 0.09 | enet | 14 | 0.08 | 8.8e-07 | 5.3 | 5.1 | 2.9e-07 | 0.06 | 0.96 | 0.00 | FALSE |
| 6 | GTEx | Skin Not Sun Exposed Suprapubic | RP11-517P14.2 | 0.11 | 0.01 | lasso | 4 | 0.09 | 1.6e-05 | 5.3 | 5.6 | 2.5e-08 | 0.06 | 0.41 | 0.03 | FALSE |
| 7 | GTEx | Skin Sun Exposed Lower leg | RP11-517P14.2 | 0.14 | 0.12 | lasso | 7 | 0.11 | 2.4e-09 | 5.0 | 5.6 | 2.2e-08 | 0.12 | 1.00 | 0.00 | FALSE |
| 8 | GTEx | Thyroid | RP11-517P14.2 | 0.12 | 0.07 | lasso | 7 | 0.06 | 4.3e-05 | 5.2 | 5.4 | 5.9e-08 | 0.02 | 0.54 | 0.02 | FALSE |