Best TWAS P=1.53e-08 · Best GWAS P=7.22e-10 conditioned to 0.0135
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | VSTM4 | 0.16 | 0.06 | enet | 12 | 0.08 | 5.8e-05 | -5.7 | 5.4 | 5.6e-08 | -0.71 | 0.04 | 0.95 | FALSE |
| 2 | GTEx | Spleen | WDFY4 | 0.39 | 0.00 | lasso | 8 | 0.03 | 5.8e-02 | -1.8 | -5.5 | 4.6e-08 | 0.48 | 0.04 | 0.66 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | C10orf72 | 0.06 | 0.02 | enet | 7 | 0.05 | 1.3e-03 | -3.9 | 5.5 | 3.3e-08 | -0.81 | 0.01 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FAM170B | 0.09 | 0.10 | blup | 65 | 0.10 | 1.1e-11 | -4.3 | -5.2 | 1.6e-07 | 0.80 | 0.29 | 0.71 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | C10orf128 | 0.11 | 0.05 | lasso | 5 | 0.06 | 1.0e-07 | -4.7 | -5.6 | 1.9e-08 | 0.68 | 0.03 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C10orf128 | 0.05 | 0.02 | blup | 59 | 0.02 | 2.9e-03 | -4.7 | -5.2 | 1.9e-07 | 0.69 | 0.01 | 0.71 | FALSE |
| 7 | The Cancer Genome Atlas | Soft Tissue Sarcoma | FAM170B | 0.07 | 0.09 | lasso | 4 | 0.07 | 4.9e-05 | -5.7 | -5.7 | 1.5e-08 | 0.94 | 0.01 | 0.98 | TRUE |