Best TWAS P=8.81e-13 · Best GWAS P=4.33e-36 conditioned to 5.62e-40
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Putamen basal ganglia | RP11-57H14.4 | 0.33 | 0.06 | lasso | 5 | 0.05 | 0.022 | -6.5 | -7.2 | 8.8e-13 | -0.11 | 0.04 | 0.16 | TRUE |
2 | GTEx | Breast Mammary Tissue (Male) | CASP7 | 0.10 | -0.01 | enet | 15 | 0.04 | 0.043 | 3.2 | -5.3 | 1.2e-07 | 0.04 | 0.05 | 0.06 | TRUE |