Best TWAS P=2.38e-13 · Best GWAS P=2.81e-19 conditioned to 3.61e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | ADD3 | 0.13 | 0.00 | enet | 29 | 0.01 | 0.02590 | -1.3 | 5.7 | 1.6e-08 | 0.28 | 0.14 | 0.04 | FALSE |
2 | NTR | Blood | DUSP5 | 0.02 | 0.00 | enet | 17 | 0.00 | 0.02070 | 1.6 | 5.2 | 1.6e-07 | 0.21 | 0.03 | 0.02 | TRUE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | DUSP5 | 0.02 | 0.03 | enet | 5 | 0.02 | 0.00071 | 7.5 | 7.3 | 2.4e-13 | 0.41 | 0.09 | 0.08 | TRUE |