[Hub]/) : Traits : Heel T-Score : ← →

chr10:122,801,759-124,889,817

Best TWAS P=9.9e-26 · Best GWAS P=3.89e-19 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PLEKHA1	0.07	0.02	enet	18	0.06	2.0e-07	8.26	-5.7	9.4e-09	0.06	0.55	0.34	FALSE
2	GTEx	Adipose Subcutaneous	ATE1	0.19	0.02	enet	34	0.06	1.1e-05	0.97	5.4	5.2e-08	-0.21	0.11	0.75	FALSE
3	GTEx	Adipose Subcutaneous	RP11-500G22.2	0.16	0.09	lasso	4	0.10	7.0e-09	6.07	-7.4	1.0e-13	0.31	0.60	0.35	FALSE
4	GTEx	Adipose Visceral Omentum	RP11-500G22.2	0.29	0.00	enet	32	0.01	7.5e-02	6.07	-6.4	1.7e-10	0.34	0.06	0.47	FALSE
5	GTEx	Adrenal Gland	RP11-500G22.2	0.45	0.03	enet	74	0.09	5.2e-04	8.83	-10.0	1.7e-23	0.27	0.05	0.66	TRUE
6	GTEx	Artery Aorta	RP11-500G22.2	0.23	0.05	lasso	7	0.05	6.8e-04	6.07	-6.7	1.7e-11	0.24	0.49	0.34	TRUE
7	GTEx	Artery Tibial	ATE1	0.19	0.02	enet	26	0.09	2.3e-07	4.75	9.7	2.9e-22	-0.53	0.03	0.94	TRUE
8	GTEx	Artery Tibial	RP11-500G22.2	0.29	0.05	enet	13	0.08	4.1e-07	6.07	-5.8	8.1e-09	0.13	0.87	0.06	TRUE
9	GTEx	Brain Caudate basal ganglia	RP11-500G22.2	0.39	0.14	lasso	6	0.18	5.7e-06	6.07	-7.5	8.7e-14	0.30	0.14	0.63	FALSE
10	GTEx	Brain Cerebellum	RP11-500G22.2	0.50	0.01	lasso	7	0.08	2.3e-03	0.33	-5.2	2.2e-07	0.10	0.08	0.33	TRUE
11	GTEx	Brain Cortex	RP11-500G22.2	0.66	-0.01	enet	36	0.01	1.5e-01	-8.68	-10.5	9.9e-26	0.46	0.05	0.60	TRUE
12	GTEx	Brain Nucleus accumbens basal ganglia	RP11-500G22.2	0.73	0.36	lasso	20	0.27	5.8e-08	6.07	-6.7	1.7e-11	0.24	0.78	0.14	FALSE
13	GTEx	Breast Mammary Tissue	RP11-500G22.2	0.28	0.04	lasso	4	0.09	3.1e-05	6.07	-9.0	2.2e-19	0.40	0.06	0.71	FALSE
14	GTEx	Colon Sigmoid	RP11-500G22.2	0.54	0.00	lasso	20	0.08	1.0e-03	-2.47	-8.6	6.6e-18	0.33	0.07	0.62	TRUE
15	GTEx	Esophagus Gastroesophageal Junction	RP11-500G22.2	0.22	0.05	lasso	4	0.12	5.1e-05	6.50	-6.6	4.6e-11	0.22	0.33	0.30	FALSE
16	GTEx	Esophagus Mucosa	RP11-500G22.2	0.23	0.03	lasso	10	0.02	1.4e-02	6.07	-7.0	2.7e-12	0.07	0.30	0.32	FALSE
17	GTEx	Esophagus Muscularis	RP11-500G22.2	0.21	0.03	lasso	8	0.07	8.1e-05	3.71	-8.6	8.1e-18	0.37	0.11	0.85	FALSE
18	GTEx	Lung	RP11-500G22.2	0.44	0.03	lasso	15	0.08	1.3e-06	6.07	-7.1	1.5e-12	0.43	0.39	0.49	TRUE
19	GTEx	Muscle Skeletal	RP11-500G22.2	0.28	0.04	lasso	9	0.09	9.5e-09	8.83	-9.5	1.5e-21	0.38	0.04	0.96	TRUE
20	GTEx	Nerve Tibial	RP11-500G22.2	0.48	0.13	enet	40	0.28	3.0e-20	6.07	-6.6	4.1e-11	0.14	0.98	0.02	FALSE
21	GTEx	Skin Sun Exposed Lower leg	RP11-500G22.2	0.22	0.12	lasso	5	0.14	2.3e-11	6.07	-8.0	1.8e-15	0.30	0.95	0.04	FALSE
22	GTEx	Testis	RP11-500G22.2	0.32	0.03	lasso	9	0.05	2.1e-03	8.83	-8.5	2.0e-17	0.33	0.04	0.92	TRUE
23	GTEx	Thyroid	RP11-500G22.2	0.32	0.08	lasso	11	0.14	8.3e-11	8.73	-7.9	3.2e-15	0.32	0.03	0.97	TRUE
24	ROSMAP	Brain Pre-frontal Cortex	RP11-500G22.2	0.55	0.31	enet	46	0.55	1.9e-85	6.07	-7.7	9.6e-15	0.30	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	BTBD16	0.05	0.04	blup	146	0.05	6.3e-10	8.51	-8.2	2.0e-16	-0.03	0.01	0.99	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	ARMS2	0.04	0.02	lasso	3	0.01	2.7e-02	7.64	7.0	2.1e-12	0.01	0.18	0.35	TRUE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ARMS2	0.23	0.20	lasso	2	0.21	7.0e-09	5.29	5.5	3.8e-08	0.00	0.73	0.22	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	BTBD16	0.31	0.31	enet	16	0.36	2.4e-39	8.52	-7.6	4.0e-14	-0.01	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Soft Tissue Sarcoma	BTBD16	0.07	0.03	blup	147	0.05	7.3e-04	7.63	-8.7	2.4e-18	-0.02	0.02	0.97	TRUE
30	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ATE1	0.24	-0.01	blup	126	0.03	5.0e-02	4.69	5.9	4.3e-09	-0.16	0.02	0.21	TRUE