[Hub]/) : Traits : Heel T-Score : ← →

chr11:29,646,947-31,288,160

Best TWAS P=2.26e-14 · Best GWAS P=3.85e-12 conditioned to 0.0209

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Colon Sigmoid	ARL14EP	0.16	0.05	lasso	13	0.10	2.6e-04	2.8	-6.3	2.8e-10	0.68	0.07	0.66	FALSE
2	GTEx	Esophagus Mucosa	ARL14EP	0.09	0.03	enet	11	0.05	1.8e-04	2.8	-5.5	4.4e-08	0.56	0.16	0.64	FALSE
3	GTEx	Spleen	ARL14EP	0.34	0.19	enet	24	0.30	1.7e-08	5.4	-5.3	1.1e-07	0.42	0.36	0.34	FALSE
4	GTEx	Stomach	ARL14EP	0.10	0.07	lasso	3	0.04	4.0e-03	-5.7	-5.7	1.1e-08	0.38	0.62	0.12	FALSE
5	GTEx	Testis	MPPED2	0.18	0.17	enet	15	0.17	6.9e-08	6.4	6.0	2.7e-09	0.02	0.14	0.86	TRUE
6	GTEx	Testis	ARL14EP	0.43	0.36	lasso	3	0.37	1.8e-17	-6.9	-6.7	2.1e-11	0.84	0.01	0.99	FALSE
7	GTEx	Thyroid	ARL14EP	0.20	0.05	lasso	6	0.09	1.0e-07	-6.5	-6.6	4.9e-11	0.79	0.01	0.99	FALSE
8	GTEx	Whole Blood	ARL14EP	0.07	0.05	lasso	2	0.05	3.3e-05	5.5	-5.5	2.8e-08	0.26	0.80	0.05	FALSE
9	METSIM	Adipose	ARL14EP	0.06	0.00	bslmm	398	0.02	2.9e-04	-6.5	-5.3	1.3e-07	0.59	0.01	0.97	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	C11orf46	0.05	0.05	lasso	5	0.06	6.2e-12	5.5	-5.2	1.5e-07	0.25	0.96	0.04	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C11orf46	0.36	0.27	lasso	5	0.30	8.3e-34	5.4	-5.3	1.1e-07	0.30	0.98	0.02	FALSE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C11orf46	0.13	0.12	lasso	3	0.11	8.9e-07	5.4	-5.4	8.4e-08	0.26	0.94	0.03	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	C11orf46	0.02	0.02	lasso	2	0.02	5.9e-03	-6.8	-6.8	8.6e-12	0.99	0.00	0.78	FALSE
14	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C11orf46	0.12	0.07	blup	34	0.07	4.4e-04	5.4	-6.8	7.6e-12	0.68	0.05	0.35	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	C11orf46	0.09	0.11	lasso	4	0.10	1.2e-11	5.4	-5.6	2.7e-08	0.29	0.98	0.02	FALSE
16	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C11orf46	0.22	0.22	lasso	3	0.20	1.1e-08	5.4	-5.4	7.0e-08	0.26	0.97	0.02	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	C11orf46	0.09	0.07	lasso	2	0.06	2.4e-07	5.4	-5.4	8.0e-08	0.26	0.95	0.02	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	C11orf46	0.12	0.06	blup	34	0.10	1.4e-09	5.4	-7.6	2.3e-14	0.71	0.69	0.31	TRUE