TWAS hub - C11orf46

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0243	0.0080	1.8e-06	0.008	0.013	0.012	0.012	0.012	6.7e-04	3.8e-05	6.4e-05	4.8e-05	8.0e-05
2	TCGA	Breast Invasive Carcinoma	0.0507	0.0208	6.4e-11	0.050	0.056	0.052	NA	0.058	1.4e-10	1.2e-11	6.1e-11	NA	6.2e-12
3	TCGA	Colon Adenocarcinoma	0.1200	0.0750	3.3e-04	0.077	0.072	0.055	NA	0.067	3.1e-05	5.7e-05	4.0e-04	NA	1.0e-04
4	TCGA	Esophageal Carcinoma	0.1660	0.0760	3.6e-04	0.075	0.109	0.092	NA	0.100	2.3e-03	2.5e-04	7.7e-04	NA	4.6e-04
5	TCGA	Head and Neck Squamous Cell Carcinoma	0.0642	0.0307	3.4e-06	0.064	0.039	0.036	NA	0.047	9.5e-08	3.0e-05	5.9e-05	NA	5.5e-06
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.3633	0.0980	0.0e+00	0.270	0.289	0.290	NA	0.297	2.4e-30	1.0e-32	7.8e-33	NA	8.3e-34
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1260	0.0580	7.9e-06	0.117	0.096	0.106	NA	0.109	3.2e-07	3.7e-06	1.2e-06	NA	8.9e-07
8	TCGA	Brain Lower Grade Glioma	0.0235	0.0162	9.8e-03	0.016	0.013	0.011	NA	0.016	5.7e-03	1.2e-02	2.0e-02	NA	5.9e-03
9	TCGA	Liver Hepatocellular Carcinoma	0.1170	0.0680	1.1e-03	0.075	0.067	0.043	NA	0.062	2.1e-04	4.4e-04	4.3e-03	NA	7.1e-04
10	TCGA	Lung Adenocarcinoma	0.0910	0.0384	3.1e-10	0.107	0.091	0.094	NA	0.099	1.9e-12	7.9e-11	4.1e-11	NA	1.2e-11
11	TCGA	Lung Squamous Cell Carcinoma	0.0523	0.0328	1.2e-03	0.022	0.021	0.015	NA	0.023	1.4e-03	1.7e-03	6.9e-03	NA	9.9e-04
12	TCGA	Ovarian Serous Cystadenocarcinoma	0.0720	0.0350	6.2e-05	0.037	0.067	0.060	NA	0.062	1.5e-03	2.5e-05	6.4e-05	NA	5.2e-05
13	TCGA	Pancreatic Adenocarcinoma	0.2210	0.0850	3.9e-07	0.216	0.160	0.191	NA	0.197	1.9e-09	3.1e-07	1.8e-08	NA	1.1e-08
14	TCGA	Prostate Adenocarcinoma	0.0899	0.0493	8.0e-06	0.066	0.052	0.054	NA	0.065	2.0e-07	3.5e-06	2.5e-06	NA	2.4e-07
15	TCGA	Stomach Adenocarcinoma	0.1130	0.0520	1.6e-06	0.054	0.085	0.092	NA	0.087	9.0e-05	9.3e-07	3.4e-07	NA	7.9e-07
16	TCGA	Testicular Germ Cell Tumors	0.2360	0.1110	2.9e-04	0.070	0.130	0.141	NA	0.096	1.8e-03	2.6e-05	1.1e-05	NA	3.0e-04
17	TCGA	Thyroid Carcinoma	0.1180	0.0520	9.1e-10	0.055	0.096	0.083	NA	0.091	4.4e-06	1.4e-09	1.8e-08	NA	3.3e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Systolic Blood Pressure	7.1	35.3	48.0	-6.9	-6.6	-5.3	-5.2	-6.8	-6.6	-6.9	-2.7	-6.0	-6.9	-4.6	-4.6	-6.9	-6.9	-5.3	-4.9	-5.9
Loneliness, isolation	7.1	9.8	18.0	2.7	2.9	2.4	3.6	3.5	3.3	3.5	-1.3	1.8	3.3	4.2	3.8	3.4	3.5	4.0	2.5	1.1
Qualifications: O levels/GCSEs or equivalent	7.0	11.1	15.3	-3.7	-3.3	-2.7	-3.8	-3.7	-3.4	-3.7	0.2	-2.5	-3.8	-3.5	-3.6	-3.7	-3.7	-3.9	-3.3	-2.1
Ever taken oral contraceptive pill	5.7	6.4	12.2	-2.2	-2.3	-2.7	-1.0	-2.7	-2.8	-2.8	-2.5	-3.1	-2.9	-1.7	-1.4	-2.8	-2.8	-2.4	-2.1	-3.5
Relative age of first facial hair	5.5	11.4	26.8	-5.2	-3.7	-2.6	-4.6	-3.6	-3.0	-3.6	0.9	-1.7	-3.4	-2.5	-3.4	-3.6	-3.6	-3.1	-4.4	-2.0
Had menopause	5.5	6.8	17.5	3.7	2.2	1.6	4.2	2.7	2.0	2.6	-2.6	0.2	2.4	2.4	3.2	2.6	2.6	2.5	3.5	0.4
Number of incorrect matches in round	5.3	8.9	13.8	3.6	3.0	2.8	3.4	3.1	3.0	3.0	-0.6	2.0	3.2	3.5	3.6	3.0	3.0	3.7	2.6	1.5
Comparative height size at age 10	4.6	25.3	35.6	2.7	5.8	5.8	4.4	5.2	5.8	5.2	1.2	4.8	5.5	5.5	5.5	5.3	5.2	6.0	5.0	4.2
Ever had hysterectomy (womb removed)	4.5	5.1	20.6	-0.4	-1.8	-1.8	0.1	-2.0	-2.0	-2.2	-4.5	-3.5	-2.2	0.4	0.7	-2.2	-2.2	-0.6	-0.7	-4.2
Sitting height	4.5	31.8	52.7	1.2	6.5	7.3	3.1	5.6	6.8	5.8	4.3	7.2	6.4	5.7	5.4	5.8	5.8	6.2	3.8	5.6
Seen doctor (GP) for nerves, anxiety, tension or depression	4.5	6.9	11.2	3.2	3.1	2.0	3.4	3.0	2.9	2.9	-0.6	1.6	2.9	2.4	2.6	3.0	2.9	2.6	2.5	1.7
Height	4.4	84.1	134.6	3.5	10.6	10.9	5.4	9.6	10.8	9.9	7.6	11.6	10.6	7.8	7.5	10.0	9.9	9.1	6.6	10.3
Ever used hormone-replacement therapy (HRT)	4.2	5.3	12.5	2.3	2.2	1.1	3.5	1.9	1.8	1.8	-3.4	-0.4	1.8	3.2	3.4	1.8	1.8	2.8	2.0	-1.0
Bilateral oophorectomy (both ovaries removed)	4.2	4.8	33.4	1.6	-0.6	-1.0	2.2	-0.6	-0.9	-0.9	-5.8	-3.3	-0.9	1.8	2.2	-0.9	-0.9	1.1	1.2	-3.7
Seen a psychiatrist for nerves, anxiety, tension or depression	3.9	5.1	9.4	1.8	2.4	2.2	2.2	2.3	2.6	2.3	-0.6	1.7	2.4	3.1	2.8	2.3	2.3	3.0	1.7	1.1
Cardiovascular Disease	3.7	12.1	22.8	-4.7	-3.3	-2.1	-2.8	-4.1	-3.4	-4.2	-3.1	-3.7	-4.1	-1.0	-1.0	-4.2	-4.2	-2.2	-3.0	-4.8
Triglycerides	3.6	5.8	11.4	-1.8	-2.3	-2.0	-1.1	-2.8	-2.8	-2.9	-2.3	-2.9	-2.9	-1.5	-0.9	-2.9	-2.9	-1.9	-2.0	-3.4
Standing height	3.6	36.1	63.0	0.7	6.9	7.9	2.8	5.9	7.3	6.1	5.0	7.9	6.7	6.0	5.5	6.2	6.1	6.5	3.8	6.3
Falls in the last year	3.5	4.7	11.7	0.9	2.1	2.5	2.3	2.0	2.2	1.9	-1.0	1.4	2.1	3.1	3.4	1.9	1.9	3.0	2.3	0.4
Reason for reducing amount of alcohol drunk: Health precaution	3.5	4.1	6.2	2.0	2.5	2.1	2.0	2.1	2.3	2.1	0.6	2.0	2.2	2.1	2.2	2.1	2.1	2.2	1.6	1.6
Alzheimer’s Disease (in mother)	3.4	4.0	6.1	-1.8	-2.2	-1.8	-2.3	-2.2	-2.0	-2.1	-0.2	-1.4	-2.3	-1.9	-2.1	-2.1	-2.1	-2.5	-2.3	-1.6
Systolic blood pressure, automated reading	3.3	9.5	14.6	-3.6	-3.8	-2.6	-2.6	-3.6	-3.6	-3.6	-1.7	-3.4	-3.6	-2.0	-2.0	-3.7	-3.6	-2.3	-2.0	-3.4
Relative age voice broke	3.3	5.1	11.4	-3.4	-2.6	-1.8	-2.6	-2.5	-2.2	-2.5	-0.6	-1.9	-2.4	-1.2	-1.6	-2.5	-2.5	-1.8	-2.4	-2.3
Hand grip strength (right)	3.2	8.6	16.3	0.0	3.1	4.0	1.0	2.8	3.6	2.9	2.2	3.9	3.2	3.4	3.0	2.9	2.9	3.5	1.7	2.9
Heel T-Score	3.1	24.6	58.2	-3.6	-5.2	-4.8	-1.8	-5.1	-5.3	-5.4	-6.8	-6.8	-5.6	-1.8	-1.3	-5.4	-5.4	-3.3	-3.6	-7.6
Chronotype (morning person)	3.0	7.0	23.6	-2.6	2.3	4.9	0.4	1.6	2.8	1.7	2.0	3.6	2.2	3.6	3.8	1.7	1.6	3.4	1.4	1.4
Myopia	2.9	4.2	9.0	-0.5	1.8	3.0	0.7	1.9	2.4	1.9	1.3	2.8	2.0	2.8	2.5	1.9	1.9	2.5	1.0	1.6
Financial difficulties in last 2 years	2.8	3.8	5.5	-2.0	-2.4	-1.5	-2.3	-2.3	-2.0	-2.3	-0.7	-1.7	-2.2	-1.0	-1.4	-2.3	-2.3	-1.4	-2.1	-2.1
Medication: Lisinopril	2.7	3.5	6.1	-2.4	-1.9	-0.8	-1.4	-2.4	-2.0	-2.4	-1.6	-2.0	-2.2	-0.7	-0.2	-2.4	-2.5	-0.9	-1.0	-2.4
Severe depression (siblings)	2.6	2.9	7.7	2.8	1.4	1.0	2.4	1.9	1.5	1.8	-1.1	0.6	1.7	1.7	2.0	1.8	1.8	1.8	1.7	0.6
Wheeze or whistling in the chest in last year	2.6	4.7	11.1	1.0	2.0	2.7	2.1	1.9	2.2	1.8	-0.8	1.4	2.0	3.2	3.3	1.8	1.8	3.1	2.4	0.7
Pulse rate, automated reading	2.5	7.9	17.8	3.0	2.5	2.1	3.2	2.9	2.9	2.7	-2.4	1.4	2.7	4.2	3.9	2.7	2.7	3.7	2.0	0.6
Risk taking	2.5	3.6	6.1	1.8	2.1	1.7	2.1	2.0	2.2	1.9	-0.3	1.5	2.1	2.5	2.4	2.0	1.9	2.4	1.1	1.0
Pack years of smoking	2.5	3.7	9.6	1.2	2.2	2.4	2.3	1.5	1.8	1.5	-1.4	0.6	1.7	2.7	3.1	1.5	1.4	2.5	2.4	-0.2
Fasting Glucose	2.4	2.8	4.1	1.6	1.8	1.6	1.8	2.0	1.9	2.0	0.0	1.7	1.6	1.6	1.6	2.0	2.0	1.4	1.4	1.5
Age at last live birth	2.3	3.4	14.5	-0.7	1.5	2.6	-0.6	1.2	1.8	1.4	3.8	3.2	1.5	0.2	0.4	1.4	1.4	0.7	0.6	3.0
Number of operations (self-reported)	2.3	3.4	16.2	-1.3	-0.5	0.6	0.5	-0.9	-0.3	-1.1	-4.0	-1.5	-0.9	2.8	2.8	-1.1	-1.1	1.4	-1.0	-3.5
Breastfed as a baby	2.2	2.7	4.8	-2.2	-1.8	-1.2	-2.1	-1.8	-1.6	-1.8	0.2	-1.2	-2.0	-1.5	-1.7	-1.8	-1.8	-1.8	-1.3	-1.1
Medication: Bendroflumethiazide	2.2	3.3	6.0	-2.5	-2.2	-1.8	-1.7	-1.9	-2.1	-1.9	-0.2	-1.5	-2.1	-1.8	-1.7	-1.9	-1.9	-2.0	-1.4	-1.5
Average weekly beer plus cider intake	2.2	3.2	5.4	-1.4	-1.8	-1.9	-0.9	-1.9	-2.2	-2.0	-1.4	-2.0	-1.9	-1.6	-1.0	-2.0	-2.0	-1.7	-1.5	-2.3
Medication: Simvastatin	2.1	3.0	8.2	-0.9	-1.7	-1.8	-0.5	-1.9	-2.0	-2.0	-2.4	-2.9	-1.9	-0.7	-0.8	-2.0	-2.0	-0.9	-0.2	-2.4
Weight	2.1	10.1	30.8	-1.9	2.3	5.5	0.4	1.9	3.4	1.9	1.1	3.7	2.4	5.5	5.2	1.8	1.8	5.2	1.5	1.0
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	4.4	-1.3	-1.3	-2.0	-0.7	-1.5	-1.4	-1.5	-2.0	-2.1	-1.5	-0.8	-1.0	-1.5	-1.5	-1.2	-1.9	-2.0
Headache pain in last month	2.1	3.6	8.3	0.6	2.3	2.2	0.5	1.8	2.2	1.9	2.8	2.9	2.2	0.9	0.9	2.0	1.9	1.3	0.5	2.7
Medication for cholesterol	2.1	3.3	6.2	1.8	1.8	1.1	0.9	2.2	2.1	2.3	1.9	2.5	2.2	0.9	0.5	2.3	2.3	1.1	0.3	2.4
Pack years adult smoking proportion	2.0	3.0	8.5	0.9	2.0	2.4	1.9	1.3	1.6	1.2	-1.0	0.7	1.5	2.5	2.9	1.3	1.2	2.4	2.0	-0.2
Commuting to job workplace: Public transport	2.0	2.4	6.4	-2.5	-2.3	-0.3	-2.4	-1.5	-1.5	-1.4	1.3	-0.2	-1.6	-1.5	-1.5	-1.6	-1.5	-1.6	-1.1	-0.3
Age started oral contraceptive pill	2.0	2.6	6.2	2.2	1.5	0.6	1.2	2.0	1.5	2.0	1.5	1.8	1.7	-0.1	0.0	2.0	2.0	0.4	1.0	2.5
Commuting to job workplace: Car/motor vehicle	1.9	2.2	4.4	1.2	2.1	1.1	1.7	1.7	1.8	1.6	-0.5	1.0	1.7	1.8	1.5	1.7	1.6	1.7	0.9	0.8
Mineral and other dietary supplements	1.9	2.5	4.0	-0.5	-1.4	-1.4	-1.2	-1.9	-1.6	-1.9	-1.4	-1.7	-1.9	-1.0	-1.0	-1.9	-1.9	-1.7	-1.7	-2.0
Medication: Blood pressure	1.9	3.7	5.8	-2.0	-2.1	-1.2	-1.3	-2.3	-2.3	-2.4	-1.3	-2.2	-2.4	-1.4	-1.0	-2.4	-2.4	-1.6	-0.7	-2.0
Lung FEV1/FVC ratio	1.8	9.3	37.1	-0.2	-2.9	-3.1	0.5	-2.6	-3.0	-2.9	-6.1	-4.7	-3.0	0.0	0.6	-2.9	-2.9	-0.9	-1.1	-5.4
Hip circumference	1.8	7.6	26.3	-2.1	1.5	5.1	0.1	1.3	2.6	1.3	1.2	3.1	1.8	4.7	4.7	1.2	1.3	4.5	1.8	0.7
Depression (self-reported)	1.8	2.2	3.8	1.9	1.3	1.3	1.3	1.6	1.4	1.6	1.2	1.6	1.8	0.7	1.0	1.6	1.6	1.4	1.5	1.8
Eye problems/disorders: None of the above	1.8	2.1	4.6	0.1	1.4	2.1	0.9	1.5	1.7	1.5	0.9	1.9	1.6	1.6	1.7	1.5	1.5	1.5	0.6	1.1
Emphysema/chronic bronchitis	1.8	2.1	4.3	0.7	1.4	2.1	1.0	1.4	1.6	1.4	0.7	1.5	1.5	1.7	1.6	1.4	1.4	1.8	1.5	1.1
Mean time to correctly identify matches	1.8	3.4	9.2	2.9	2.1	1.4	2.5	1.8	1.6	1.8	0.0	0.9	1.9	0.6	1.4	1.8	1.8	1.4	3.0	1.9
Number of self-reported non-cancer illnesses	1.8	3.2	10.6	0.1	1.6	2.4	1.5	1.1	1.7	1.1	-1.4	0.8	1.3	3.2	3.3	1.1	1.0	2.8	1.6	-0.3
Hearing aid user	1.8	2.0	6.9	-0.9	-1.7	-1.5	-0.3	-1.2	-1.4	-1.3	-2.6	-2.2	-1.5	-0.2	-0.2	-1.4	-1.3	-0.5	-0.6	-2.1
Serious illness, injury or assault to yourself	1.7	2.1	6.0	0.7	1.2	0.8	1.9	1.3	1.3	1.2	-1.7	0.4	1.4	2.4	2.3	1.2	1.2	2.3	1.0	-0.2
Alcohol usually taken with meals	1.7	2.8	5.3	1.0	1.7	1.9	1.5	1.8	1.9	1.8	0.0	1.6	1.8	2.3	2.1	1.8	1.8	2.0	1.2	0.8
Had other major operations	1.7	2.1	7.3	0.6	1.3	1.6	1.4	1.1	1.4	1.0	-1.8	0.4	1.0	2.7	2.6	1.0	1.0	2.0	0.4	-0.6
Mouth/teeth dental problems: Dentures	1.7	2.9	7.4	2.3	1.4	1.1	2.0	2.1	1.5	2.1	-0.0	1.0	1.8	0.9	1.2	2.0	2.1	1.3	2.7	1.7
Leg fat-free mass (left)	1.6	8.2	27.2	-2.3	2.1	5.2	-0.0	1.5	3.0	1.6	1.9	3.6	2.2	4.5	4.3	1.5	1.5	4.5	1.7	1.4
Townsend deprivation index at recruitment	1.6	2.2	3.8	1.9	1.3	1.4	1.4	1.6	1.5	1.6	0.4	1.4	1.7	1.2	1.6	1.6	1.6	1.7	1.6	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	8.0	1.6	1.0	0.3	2.1	0.9	0.8	0.8	-2.8	-0.8	0.9	2.3	2.1	0.8	0.8	2.0	0.6	-1.3
Trunk fat mass	1.6	7.0	24.0	-1.3	1.8	4.4	0.3	1.6	2.9	1.6	0.6	3.0	1.9	4.9	4.3	1.5	1.5	4.3	1.0	0.8
Blood clot in the leg (DVT)	1.6	2.1	6.3	-0.8	1.1	2.5	-0.1	0.9	1.6	0.9	0.9	2.2	1.2	2.5	2.2	0.8	0.9	2.0	-0.4	0.4
Medication: Amlodipine	1.6	2.3	3.4	-1.8	-1.2	-1.1	-1.1	-1.8	-1.6	-1.8	-0.6	-1.5	-1.8	-1.5	-1.3	-1.8	-1.8	-1.9	-1.0	-1.1
Whole body fat-free mass	1.6	8.9	27.2	-2.1	2.2	5.2	0.1	1.8	3.2	1.9	1.9	3.8	2.4	4.7	4.4	1.8	1.8	4.6	1.7	1.5
Leg fat-free mass (right)	1.6	8.5	27.6	-2.0	2.3	5.2	0.2	1.7	3.1	1.8	2.2	3.8	2.4	4.3	4.2	1.8	1.8	4.4	1.9	1.6
Osteoarthritis (self-reported)	1.6	2.1	3.8	0.5	1.5	1.8	0.6	1.4	1.5	1.5	1.9	1.9	1.5	0.7	0.9	1.5	1.5	1.1	1.6	2.0
Leg predicted mass (right)	1.6	8.5	27.4	-1.9	2.3	5.2	0.2	1.7	3.1	1.8	2.0	3.7	2.4	4.3	4.3	1.7	1.7	4.4	1.9	1.6
Basal metabolic rate	1.6	8.9	28.0	-2.3	2.1	5.3	0.0	1.6	3.2	1.7	1.7	3.7	2.3	4.9	4.5	1.7	1.7	4.7	1.5	1.3
HbA1C	1.5	1.7	3.2	-1.8	-1.2	-0.9	-1.8	-1.5	-1.2	-1.4	1.1	-0.6	-1.4	-0.9	-1.3	-1.4	-1.4	-1.0	-1.6	-0.7
Leg predicted mass (left)	1.5	8.0	26.9	-2.3	2.0	5.2	-0.1	1.4	2.9	1.5	1.9	3.6	2.1	4.4	4.3	1.5	1.5	4.4	1.7	1.3
Trunk fat-free mass	1.5	8.6	25.5	-2.1	2.2	5.0	0.2	1.9	3.2	1.9	1.9	3.8	2.4	4.6	4.2	1.9	1.9	4.5	1.6	1.6
Alcohol intake versus 10 years previously	1.5	2.3	6.3	-0.2	-1.4	-2.2	0.1	-1.3	-1.7	-1.4	-2.4	-2.5	-1.5	-0.9	-0.7	-1.5	-1.4	-0.8	-0.1	-2.0
Wears glasses or contact lenses	1.5	1.8	3.2	1.2	1.5	1.3	1.7	1.4	1.4	1.3	-0.4	1.0	1.5	1.6	1.8	1.3	1.3	1.6	1.0	0.6
Trunk predicted mass	1.4	8.2	24.3	-2.1	2.1	4.9	0.1	1.8	3.1	1.9	1.8	3.7	2.3	4.5	4.1	1.8	1.8	4.4	1.6	1.5
Age at first live birth	1.4	2.5	16.8	-2.2	-0.0	1.5	-2.3	-0.2	0.4	-0.0	4.1	2.3	0.0	-1.1	-1.1	-0.0	-0.0	-0.8	-0.8	2.1
Whole body fat mass	1.4	5.7	22.1	-1.2	1.4	3.9	0.4	1.3	2.5	1.2	-0.0	2.5	1.6	4.7	4.2	1.2	1.2	4.1	0.8	0.2
Supplements: Vitamin C	1.4	1.7	4.4	-0.8	1.2	1.7	0.1	1.2	1.4	1.3	1.8	2.1	1.4	1.1	0.8	1.3	1.3	1.1	0.1	1.4
Back pain experienced in last month	1.4	2.0	5.0	-0.1	2.0	2.2	0.5	1.1	1.8	1.1	1.2	1.9	1.6	1.6	1.6	1.2	1.1	1.7	0.0	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.0	5.8	-0.8	-1.7	-1.7	-1.2	-1.9	-2.1	-1.9	-0.2	-1.7	-2.0	-2.4	-1.8	-1.9	-1.9	-2.4	-0.9	-1.3
Whole body water mass	1.4	8.2	25.5	-2.1	2.1	5.0	0.1	1.6	3.0	1.7	1.7	3.6	2.2	4.5	4.3	1.7	1.7	4.4	1.6	1.3
Reaction Time	1.3	2.5	5.4	2.2	1.9	1.4	1.9	1.6	1.5	1.5	0.3	1.0	1.7	0.7	1.2	1.6	1.5	1.3	2.3	1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.1	16.6	-0.7	-1.0	-1.1	1.0	-1.3	-1.4	-1.5	-4.1	-2.9	-1.4	0.4	1.0	-1.5	-1.5	0.0	-0.4	-3.2
Pulse rate	1.3	2.2	13.1	1.5	0.6	-0.3	1.5	0.8	0.9	0.6	-3.6	-0.7	0.5	2.8	1.9	0.6	0.6	1.7	-0.6	-1.5
Angina (self-reported)	1.3	1.7	5.6	-0.4	-1.2	-1.9	-0.2	-0.9	-1.1	-1.0	-2.4	-1.9	-1.3	0.1	-0.4	-1.0	-1.0	-0.6	-1.7	-2.1
Number of full sisters	1.3	1.6	3.9	-0.8	-1.3	-1.2	-0.6	-1.4	-1.3	-1.5	-1.7	-1.8	-1.4	-0.4	-0.4	-1.4	-1.5	-0.7	-0.9	-2.0
Had major operations	1.3	1.6	7.7	-2.8	-1.1	0.9	-1.4	-1.2	-0.4	-1.2	-0.4	0.2	-1.0	1.3	1.1	-1.3	-1.2	0.5	-1.4	-1.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	4.9	1.6	1.4	1.2	1.4	1.3	1.1	1.3	0.5	0.9	1.2	0.5	0.9	1.3	1.3	0.8	2.2	1.4
Mood swings	1.3	2.3	5.8	2.2	1.4	0.2	2.4	1.3	1.2	1.2	-2.3	-0.3	1.3	1.9	2.1	1.2	1.2	1.7	0.5	-0.8
Friendships satisfaction	1.3	1.7	3.3	1.2	1.7	1.7	1.3	1.0	1.2	0.9	0.3	0.9	1.4	1.3	1.6	1.0	0.9	1.7	1.8	0.8
Crohns Disease (2012)	1.2	1.9	3.5	-0.4	-1.7	-1.9	-1.5	-1.3	-1.5	-1.3	-0.2	-1.3	-1.5	-1.6	-1.9	-1.3	-1.3	-1.8	-1.0	-0.8
Hand grip strength (left)	1.2	3.3	7.3	-0.0	1.8	2.3	0.2	1.7	2.2	1.7	2.1	2.7	1.9	1.8	1.4	1.7	1.7	2.0	0.9	2.2
Age when periods started (menarche)	1.2	3.0	14.4	-1.3	0.9	1.1	-1.4	1.2	1.6	1.4	3.8	3.0	1.2	-0.0	-0.9	1.4	1.4	-0.1	-0.7	3.0
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	14.2	-0.4	-0.8	-1.5	1.1	-1.1	-1.3	-1.3	-3.8	-2.8	-1.2	0.1	0.5	-1.2	-1.3	-0.2	-0.2	-2.9
Waist circumference	1.2	4.3	19.9	-2.4	0.3	3.3	-0.3	0.1	1.4	0.0	-1.1	1.2	0.4	4.5	4.1	-0.1	-0.0	3.6	0.2	-1.4
Hair/balding pattern: Pattern 3	1.2	1.9	3.8	-0.3	-1.4	-2.0	-0.9	-1.2	-1.5	-1.3	-1.1	-1.8	-1.4	-1.3	-1.6	-1.2	-1.2	-1.6	-1.1	-1.3
Shortness of breath walking on level ground	1.2	1.5	4.4	-1.5	-0.9	-0.8	-0.9	-1.1	-0.6	-1.2	-1.7	-1.1	-1.2	0.6	0.1	-1.1	-1.2	-0.4	-2.1	-2.1
Arm predicted mass (right)	1.2	6.1	18.1	-1.9	1.7	4.3	0.1	1.4	2.6	1.5	1.1	2.9	1.9	4.3	4.0	1.4	1.4	4.0	1.1	0.6
Hypertension (Self-reported)	1.2	3.5	9.4	-2.2	-1.3	-1.0	-0.5	-2.1	-1.6	-2.2	-3.0	-2.5	-2.0	0.3	0.3	-2.1	-2.2	-0.5	-0.9	-3.1
Arm fat mass (left)	1.2	5.1	21.4	-1.6	1.0	3.8	0.3	0.8	2.1	0.8	-0.5	2.0	1.2	4.6	4.3	0.7	0.8	4.0	0.8	-0.4
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	4.9	-0.9	0.9	2.2	-0.3	0.6	1.3	0.7	0.9	2.0	1.0	2.1	1.9	0.6	0.6	1.7	-0.5	0.4
Type 2 Diabetes (T2D) (2018)	1.1	2.0	11.8	-0.4	-0.8	-0.0	0.5	-0.5	-0.3	-0.6	-3.4	-1.2	-0.6	2.3	2.0	-0.7	-0.6	1.3	-0.4	-2.5
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.9	1.8	0.8	0.5	2.0	0.9	0.5	0.8	-1.8	-0.4	0.7	1.1	1.5	0.8	0.8	1.2	2.2	-0.1
Trunk fat percentage	1.1	4.3	15.4	-0.7	1.5	3.4	0.3	1.3	2.3	1.2	0.3	2.4	1.5	3.9	3.4	1.2	1.2	3.3	0.6	0.6
Hair/balding pattern: Pattern 2	1.1	1.3	2.1	-0.7	-1.4	-1.5	-0.8	-1.2	-1.4	-1.2	-0.5	-1.3	-1.2	-1.2	-1.2	-1.2	-1.2	-1.1	-1.1	-1.1
Allergy	1.1	2.5	5.6	-0.9	-1.8	-2.4	-1.4	-1.3	-1.6	-1.3	-0.0	-1.3	-1.6	-2.0	-2.3	-1.3	-1.2	-2.2	-1.9	-0.8
Diabetes (self-reported)	1.1	1.7	7.3	1.6	0.5	0.1	2.0	1.0	0.7	0.8	-2.7	-0.6	0.8	1.8	1.7	0.8	0.8	1.6	1.1	-0.6
Arm fat mass (right)	1.1	4.7	19.9	-1.8	0.8	3.8	0.0	0.7	1.9	0.6	-0.3	1.9	1.0	4.5	4.1	0.5	0.6	3.8	0.8	-0.4
Peak expiratory flow (PEF)	1.1	2.5	9.0	-1.0	1.4	2.6	-1.0	0.7	1.7	0.8	3.0	2.8	1.1	1.5	1.2	0.8	0.8	1.5	-0.5	1.6
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.4	-0.8	-1.5	-1.8	-1.2	-1.0	-1.3	-1.0	-0.2	-0.9	-1.2	-0.9	-1.3	-1.1	-1.0	-1.1	-1.9	-1.2
Birth weight	1.1	2.4	6.1	-0.7	-1.3	-1.4	-1.9	-1.5	-1.4	-1.4	1.7	-0.5	-1.4	-2.5	-2.5	-1.4	-1.4	-2.1	-1.0	0.2
Arm fat-free mass (right)	1.1	5.7	17.6	-2.0	1.6	4.2	-0.0	1.2	2.5	1.3	1.1	2.9	1.7	4.2	3.9	1.2	1.2	3.9	0.8	0.5
Exposure to tobacco smoke outside home	1.1	1.5	3.9	-1.1	0.8	1.0	-0.2	1.3	1.3	1.4	2.0	1.6	1.2	0.5	-0.0	1.4	1.4	0.8	0.8	1.9
Pulse wave peak to peak time	1.1	1.4	5.1	1.5	1.0	0.5	0.4	1.1	0.9	1.2	1.8	1.3	1.1	-0.6	-0.5	1.2	1.2	0.1	0.9	2.3
Medication: Blood pressure	1.1	1.9	7.2	-1.4	-1.3	-1.2	-0.2	-1.2	-1.1	-1.3	-2.7	-2.1	-1.3	0.4	0.2	-1.3	-1.3	-0.1	-0.5	-2.4
Average weekly red wine intake	1.1	1.6	9.4	-1.2	0.8	1.7	-1.2	0.5	1.0	0.6	3.1	2.3	0.7	0.1	-0.2	0.6	0.6	0.0	-0.2	1.8
Diabetes diagnosed by doctor	1.1	1.8	10.9	1.1	0.1	-0.1	1.8	0.6	0.4	0.5	-3.3	-1.0	0.4	2.1	1.9	0.4	0.5	1.6	0.7	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	3.6	-1.9	-0.9	-1.1	-1.2	-1.1	-0.9	-1.0	-0.3	-1.0	-1.0	-0.6	-1.0	-1.0	-1.0	-0.8	-1.6	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.4	-0.1	1.3	1.3	0.4	1.1	1.6	1.1	0.8	1.5	1.1	1.3	0.9	1.2	1.1	1.4	0.1	1.4
Illnesses of father: None of the above (group 1)	1.1	1.4	2.3	1.1	1.5	1.1	0.9	1.3	1.5	1.3	0.4	1.3	1.3	1.2	0.9	1.3	1.3	1.0	0.8	1.3
Arm fat-free mass (left)	1.1	5.5	18.5	-2.3	1.5	4.3	-0.2	1.0	2.4	1.0	1.1	2.8	1.5	4.1	3.9	1.0	1.0	3.8	0.9	0.5
Basal cell carcinoma (self-reported)	1.1	1.3	3.2	-0.4	1.0	0.9	-0.4	1.0	1.4	1.1	1.3	1.8	1.2	1.5	0.5	1.1	1.1	1.3	-1.7	0.8
Arm predicted mass (left)	1.1	5.5	17.9	-2.3	1.4	4.2	-0.3	1.0	2.3	1.1	1.1	2.8	1.5	4.1	3.8	1.0	1.0	3.9	0.8	0.5
Depression (Nagel 2018)	1.0	1.5	7.5	1.5	0.6	-0.1	1.6	0.5	0.5	0.4	-2.7	-0.9	0.5	2.0	1.6	0.4	0.4	1.6	-0.3	-1.4
Neuroticism (2016)	1.0	1.4	2.9	0.8	1.7	1.3	1.1	1.2	1.3	1.2	0.3	1.2	1.5	1.1	1.1	1.3	1.2	1.3	1.1	1.0
BMI	1.0	5.6	15.4	-3.9	-2.3	1.6	-2.0	-2.1	-0.8	-2.2	-2.5	-0.9	-2.0	3.3	2.9	-2.4	-2.3	2.0	-0.7	-3.6
Frequency of depressed mood in last 2 weeks	1.0	1.4	4.5	1.1	0.7	0.1	1.4	0.8	0.9	0.7	-2.0	-0.4	0.9	2.1	1.6	0.7	0.7	1.9	-0.1	-0.9
Taking other prescription medications	1.0	1.5	3.3	0.2	1.2	1.8	0.9	1.1	1.4	1.0	0.1	1.1	1.2	1.6	1.7	1.0	1.0	1.7	1.4	0.9
High blood pressure	1.0	2.7	7.8	-2.0	-1.0	-0.5	-0.3	-1.9	-1.4	-2.0	-2.8	-2.1	-1.8	0.5	0.7	-1.9	-2.0	-0.2	-0.6	-2.8
Supplements: Glucosamine	1.0	1.3	3.2	1.5	1.2	0.6	1.8	1.4	0.9	1.3	-0.0	0.5	1.2	0.7	1.0	1.3	1.3	1.2	1.4	0.7
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	4.2	1.0	1.4	0.5	1.6	0.9	1.2	0.8	-1.8	-0.1	1.0	2.0	1.8	0.9	0.8	1.7	0.4	-0.6
Time employed in main current job	1.0	1.2	3.8	1.5	1.0	-0.2	2.0	1.5	0.9	1.4	-1.1	0.3	1.1	0.7	0.7	1.4	1.4	0.6	0.6	0.8
Medication: Cholesterol lowering	1.0	1.6	4.2	-0.6	-1.2	-1.5	-0.3	-1.2	-1.3	-1.3	-2.0	-2.0	-1.3	-0.2	-0.3	-1.3	-1.3	-0.6	-0.6	-2.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	5.0	-0.2	-0.5	-0.2	-0.0	-1.2	-0.8	-1.3	-1.8	-1.2	-1.0	0.8	1.0	-1.2	-1.3	0.3	-0.5	-2.2
Ever had bowel cancer screening	1.0	1.2	5.9	0.8	0.5	0.3	1.6	0.5	0.3	0.3	-2.4	-1.0	0.3	1.5	1.5	0.4	0.3	1.2	1.5	-1.0
Guilty feelings	1.0	1.5	2.8	0.8	1.7	1.1	0.9	1.4	1.6	1.4	0.3	1.3	1.5	1.5	1.2	1.4	1.4	1.2	-0.1	0.6
High cholesterol (Self-reported)	1.0	1.9	3.5	-1.2	-1.2	-0.7	-0.9	-1.8	-1.5	-1.9	-1.3	-1.8	-1.6	-0.4	-0.3	-1.8	-1.9	-0.6	-0.2	-1.9
Alcohol drinker status: Never	1.0	1.2	3.7	1.3	0.7	0.5	0.7	1.3	0.9	1.3	1.2	1.0	1.2	0.0	-0.1	1.3	1.3	0.7	1.5	1.9
Commuting to job workplace: Cycle	1.0	1.2	2.3	-1.1	-0.9	-0.8	-0.4	-1.3	-1.3	-1.3	-0.7	-1.3	-1.0	-1.1	-0.5	-1.2	-1.3	-1.0	-0.8	-1.5
Age at First Birth	0.9	1.4	6.5	-0.9	1.1	1.2	-0.5	0.8	1.1	0.9	2.5	2.0	1.0	0.3	-0.1	0.9	0.9	0.5	-0.3	1.8
Body Mass Index (BMI) (2010)	0.9	1.2	3.8	-0.8	1.1	1.5	0.0	0.8	1.4	0.8	0.3	1.4	1.0	1.9	1.5	0.8	0.8	1.7	-0.2	0.4
Coronary Artery Disease (CAD)	0.9	1.1	2.6	-1.5	-1.3	-0.6	-0.7	-1.0	-1.1	-1.0	-0.9	-0.9	-1.3	-0.5	-0.1	-1.1	-1.0	-1.0	-0.9	-1.6
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.6	-1.1	-1.2	-1.1	-1.1	-1.3	-1.2	-1.3	-0.3	-1.1	-1.2	-0.8	-1.0	-1.3	-1.3	-0.9	-1.0	-1.1
Illnesses of siblings	0.9	1.3	3.6	0.2	-0.9	-0.9	-1.6	-0.9	-0.9	-0.8	1.6	-0.0	-0.8	-1.8	-1.9	-0.8	-0.8	-1.5	-1.1	0.4
Pulse wave Arterial Stiffness index	0.9	1.1	4.3	-1.6	-0.7	-0.3	-0.3	-0.9	-0.6	-1.0	-1.6	-0.9	-0.8	1.0	0.7	-1.0	-1.0	0.2	-1.0	-2.1
Ever highly irritable/argumentative for 2 days	0.9	1.0	3.5	0.7	0.7	0.1	1.3	0.7	0.8	0.6	-1.8	-0.2	0.6	1.9	1.6	0.6	0.6	1.5	0.2	-0.8
High blood pressure (siblings)	0.9	1.2	3.6	-0.8	-1.0	-1.0	0.0	-1.1	-1.2	-1.2	-1.7	-1.9	-1.2	-0.7	-0.3	-1.1	-1.2	-0.8	0.1	-1.6
Number of full brothers	0.9	1.1	4.7	-0.5	0.8	1.2	1.1	0.5	0.7	0.4	-0.8	0.5	0.7	2.0	2.2	0.4	0.4	1.8	0.2	-0.8
Leg fat mass (right)	0.9	3.5	17.3	-1.6	0.3	2.9	-0.1	0.3	1.4	0.3	-1.1	1.1	0.6	4.2	3.7	0.2	0.2	3.4	0.4	-1.0
Leg pain on walking	0.9	1.2	3.4	0.1	1.0	1.6	0.7	0.7	1.1	0.7	0.1	0.9	1.0	1.8	1.8	0.7	0.7	1.8	1.1	0.2
Commuting to job workplace: Walk	0.9	1.0	2.9	0.3	0.5	1.2	-0.2	0.9	1.0	0.9	1.7	1.4	1.0	0.4	0.2	0.9	0.9	0.8	1.1	1.7
Medication: Gliclazide	0.9	1.0	3.1	1.6	0.5	-0.8	1.5	1.1	0.6	1.0	-1.8	-0.6	0.7	1.0	0.4	1.0	1.0	0.8	0.7	-0.0
Supplements: Fish oil (including cod liver oil)	0.9	1.1	8.0	-1.0	0.2	0.6	-0.8	0.5	0.4	0.6	2.8	1.6	0.6	-0.5	-0.8	0.5	0.6	0.3	0.2	2.0
Unable to work because of sickness or disability	0.9	1.1	3.7	0.9	1.1	0.9	1.5	0.5	0.7	0.4	-1.8	-0.2	0.6	1.7	1.9	0.4	0.3	1.3	0.7	-0.8
Vascular/heart problems diagnosed by doctor	0.9	2.4	9.3	1.5	0.8	0.4	-0.0	1.6	1.1	1.7	3.1	2.1	1.5	-0.9	-1.0	1.6	1.7	-0.1	0.4	2.8
Heart attack/myocardial infarction (self-reported)	0.9	1.2	5.1	-0.3	-1.3	-1.3	-0.3	-0.8	-0.7	-0.9	-2.3	-1.6	-1.0	0.8	0.0	-0.9	-0.9	0.1	-0.8	-1.8
Leg fat mass (left)	0.9	3.4	16.7	-1.4	0.4	2.9	0.0	0.4	1.4	0.3	-1.0	1.2	0.6	4.1	3.6	0.3	0.3	3.4	0.4	-0.9
Schizophrenia vs Biploar Disorder	0.8	1.0	3.4	1.8	-0.4	-1.1	0.3	1.2	0.1	1.2	0.8	0.4	0.6	-1.0	-1.4	1.1	1.2	-0.6	0.3	1.5
Schizophrenia (2014)	0.8	1.8	9.2	3.0	0.1	-2.2	1.1	1.0	-0.2	1.0	0.4	-0.3	0.5	-1.8	-1.9	1.0	1.0	-1.1	0.5	1.5
Respiratory disease	0.8	1.9	3.8	1.4	1.2	1.6	1.3	1.3	1.4	1.2	-0.4	0.9	1.3	1.9	1.8	1.2	1.2	1.9	1.4	0.8
Diabetes (mother)	0.8	1.0	3.5	0.2	0.6	0.4	1.3	0.8	0.9	0.7	-1.9	-0.1	0.6	1.7	1.7	0.7	0.7	1.3	-0.1	-0.7
Hearing difficulty/problems with background noise	0.8	1.3	3.0	-0.3	0.9	1.7	0.4	1.1	1.4	1.1	0.5	1.5	1.2	1.7	1.6	1.1	1.1	1.6	0.1	0.6
Heart attack	0.8	1.0	3.9	-0.6	-1.2	-1.3	-0.6	-0.7	-0.6	-0.8	-2.0	-1.4	-1.0	0.8	-0.1	-0.8	-0.8	0.1	-1.2	-1.6
Impedance of arm (left)	0.8	3.8	12.0	2.5	2.4	0.1	1.4	2.2	1.8	2.2	2.1	1.8	2.0	-0.9	-1.1	2.4	2.3	-0.4	0.8	3.5
Forced vital capacity (FVC), Best measure	0.8	3.1	19.4	-2.7	0.3	1.5	-2.6	-1.1	-0.1	-0.8	4.4	2.0	-0.4	-1.6	-1.2	-0.8	-0.9	-1.1	-1.0	1.6
Comparative body size at age 10	0.8	2.3	6.6	-2.2	-1.8	-0.0	-1.1	-1.5	-1.1	-1.5	-2.1	-1.4	-1.6	1.0	0.8	-1.6	-1.6	0.1	-1.1	-2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	2.1	0.3	-1.0	-0.9	-0.3	-1.0	-1.0	-1.1	-1.4	-1.3	-1.1	-0.1	-0.1	-1.1	-1.1	-0.3	-0.5	-1.4
Alcohol intake frequency.	0.8	1.8	7.3	2.0	1.2	0.8	2.0	1.4	0.9	1.3	-0.4	0.4	1.4	0.4	1.0	1.3	1.3	1.0	2.7	1.2
Suffer from ‘nerves’	0.8	1.3	2.0	1.2	1.4	0.7	0.9	1.3	1.4	1.3	0.6	1.1	1.4	1.1	0.6	1.4	1.3	1.2	0.6	1.4
Financial situation satisfaction	0.8	1.0	2.4	-1.6	-0.8	-0.4	-1.4	-1.3	-0.8	-1.3	0.1	-0.6	-1.0	-0.2	-0.5	-1.2	-1.3	-0.4	-1.4	-1.2
Irritability	0.8	1.4	3.6	0.8	1.6	1.0	0.8	1.2	1.7	1.2	-0.2	1.1	1.2	1.9	1.4	1.3	1.2	1.4	-0.7	0.2
Schizophrenia (2018)	0.7	1.4	6.5	2.6	0.5	-1.2	1.4	1.4	0.4	1.4	0.2	0.3	0.9	-1.0	-1.0	1.3	1.4	-0.6	0.6	1.5
Ulcerative Colitis	0.7	1.1	6.2	2.5	0.4	-0.3	1.6	0.6	0.1	0.5	-1.3	-0.9	0.4	0.2	0.5	0.5	0.5	0.5	2.2	0.1
Lung FVC	0.7	3.5	9.0	-2.1	-1.1	-0.1	-2.5	-1.9	-1.5	-1.7	3.0	0.1	-1.5	-3.0	-2.3	-1.7	-1.7	-2.5	-0.7	0.5
Maternal smoking around birth	0.7	1.1	3.8	0.3	0.8	1.0	1.2	0.7	0.9	0.6	-1.2	0.4	0.8	1.9	2.0	0.6	0.6	1.6	0.2	-0.6
Qualifications: CSEs or equivalent	0.7	0.9	2.3	-1.5	-1.0	-0.3	-1.3	-1.2	-0.8	-1.2	-0.1	-0.4	-1.0	0.0	-0.2	-1.2	-1.2	-0.3	-1.4	-1.2
Forced vital capacity (FVC)	0.7	2.9	20.2	-1.5	1.5	2.5	-1.4	0.1	1.1	0.3	4.5	2.7	0.8	-0.6	-0.2	0.3	0.2	0.2	0.3	2.4
Neuroticism score	0.7	1.6	3.6	1.3	1.9	0.7	1.3	1.4	1.6	1.4	-0.3	0.9	1.5	1.5	1.1	1.4	1.4	1.2	-0.3	0.4
Impedance of arm (right)	0.7	3.2	11.2	2.6	2.0	-0.1	1.3	2.0	1.5	2.0	1.8	1.5	1.7	-1.1	-1.3	2.1	2.0	-0.5	1.1	3.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	9.0	-2.5	-0.1	1.1	-2.3	-1.5	-0.5	-1.3	3.0	1.1	-0.9	-1.3	-0.9	-1.3	-1.4	-1.1	-1.3	0.4
Hair/balding pattern: Pattern 4	0.7	1.6	4.3	0.9	1.3	1.6	1.4	1.1	1.2	1.1	-0.2	0.9	1.2	1.2	1.8	1.1	1.1	1.5	2.1	0.7
Loud music exposure frequency	0.7	0.8	2.6	-0.9	-1.2	-0.2	-1.6	-0.9	-0.9	-0.9	1.4	0.4	-0.7	-0.8	-0.7	-1.0	-0.9	-0.6	-0.6	-0.1
Chest pain or discomfort	0.7	1.0	5.9	0.9	-0.3	-0.7	1.2	-0.4	-0.7	-0.5	-2.4	-1.5	-0.4	0.4	0.9	-0.5	-0.5	0.3	0.0	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.6	1.9	0.8	0.2	0.9	0.8	0.8	0.7	-0.8	0.3	0.6	1.5	0.9	0.7	0.7	1.3	0.5	0.3
Arm fat percentage (left)	0.7	2.6	12.9	-1.2	0.4	2.5	0.1	0.3	1.3	0.2	-0.9	1.1	0.5	3.6	3.2	0.2	0.2	2.9	0.3	-0.7
Osteoporosis (self-reported)	0.7	0.9	3.2	1.8	0.9	0.6	1.5	1.2	0.7	1.1	-0.2	0.6	1.0	0.2	0.7	1.1	1.2	0.3	0.7	0.7
Alzheimer’s Disease (in father)	0.6	0.6	1.4	0.2	0.8	1.2	0.3	0.8	0.9	0.8	0.5	1.0	0.9	1.0	0.9	0.8	0.8	1.0	0.2	0.4
Major Depression (MDD)	0.6	0.7	2.6	1.1	1.0	1.4	1.2	0.4	0.6	0.4	-0.9	0.3	0.7	1.1	1.6	0.4	0.4	0.8	0.4	-0.3
Allergy or Eczema	0.6	1.5	4.2	1.0	1.3	1.0	1.1	1.3	1.1	1.3	0.7	1.0	1.4	0.6	0.6	1.3	1.3	1.1	2.0	1.6
Angina	0.6	0.7	3.9	-0.2	-0.6	-1.2	0.2	-0.3	-0.4	-0.4	-2.0	-1.1	-0.6	0.7	0.1	-0.4	-0.4	0.1	-1.3	-1.5
Medication for hormone replacement therapy	0.6	0.6	4.3	0.7	-0.2	-0.3	1.0	-0.2	-0.4	-0.3	-2.1	-1.3	-0.3	0.5	0.8	-0.3	-0.3	0.2	0.6	-1.3
Medication: Metformin	0.6	0.8	6.0	0.8	-0.8	-1.2	1.0	0.3	-0.3	0.2	-2.4	-1.1	-0.0	0.9	0.6	0.1	0.2	0.7	0.1	-1.1
Stomach or abdominal pain in last month	0.6	0.8	2.2	-0.1	1.0	1.5	0.4	0.7	1.0	0.8	0.8	1.3	1.0	0.7	1.1	0.8	0.8	0.8	0.5	0.8
Body mass index (BMI)	0.6	2.5	9.6	-2.2	-0.8	2.1	-0.8	-0.8	0.2	-0.8	-1.2	0.2	-0.5	3.1	2.9	-0.9	-0.9	2.5	-0.1	-1.9
Fluid intelligence score	0.6	1.2	3.6	-0.7	-0.7	-1.2	-0.9	-1.0	-1.0	-1.0	0.5	-0.6	-1.0	-1.9	-1.6	-0.9	-1.0	-1.7	-1.2	0.0
Arm fat percentage (right)	0.6	2.4	11.9	-1.1	0.3	2.5	-0.0	0.3	1.2	0.2	-0.8	1.1	0.4	3.5	3.1	0.1	0.2	2.9	0.5	-0.6
Happiness	0.6	0.8	2.2	1.3	0.6	-0.3	1.3	0.6	0.4	0.5	-1.5	-0.4	0.7	1.3	1.0	0.5	0.5	1.4	0.1	-0.6
Illnesses of mother	0.6	0.7	1.4	0.7	0.8	0.6	1.2	1.0	0.9	1.0	-0.6	0.4	1.0	0.8	1.0	1.0	1.0	0.9	0.5	0.4
Length of working week for main job	0.6	0.7	2.3	-0.9	0.8	1.3	0.3	0.5	0.9	0.4	-0.2	0.7	0.6	1.5	1.3	0.5	0.4	1.2	-0.2	-0.0
Body fat percentage	0.6	2.4	11.8	-0.9	0.6	2.4	0.0	0.6	1.5	0.5	-0.5	1.4	0.7	3.4	2.9	0.4	0.5	2.8	0.0	-0.3
Neck or shoulder pain in last month	0.6	0.9	2.2	-0.9	-0.6	-1.0	-0.0	-0.9	-0.9	-0.9	-1.5	-1.4	-0.9	-0.4	-0.4	-0.9	-0.9	-0.7	-1.0	-1.4
Medication: Seretide 50 evohaler	0.6	0.7	1.5	-0.8	0.5	1.2	-0.1	0.6	0.9	0.6	0.8	1.2	0.7	1.1	0.8	0.6	0.6	1.0	0.4	0.8
Family relationship satisfaction	0.6	0.7	3.8	0.3	0.2	-0.2	0.8	-0.1	0.0	-0.2	-1.9	-0.6	-0.0	1.4	1.2	-0.2	-0.2	0.9	-0.9	-1.5
Mother’s age at death	0.6	0.7	3.4	1.8	0.5	0.1	1.5	0.6	0.3	0.5	-1.4	-0.6	0.5	0.5	0.7	0.6	0.5	0.7	1.3	-0.0
Eye problems/disorders: Glaucoma	0.6	0.7	1.6	0.8	-0.9	-1.1	-0.3	-0.7	-1.0	-0.7	-0.5	-1.3	-0.8	-1.2	-0.9	-0.7	-0.7	-1.0	0.2	-0.8
Ever smoked	0.6	1.1	1.7	-0.5	-0.9	-1.0	-0.8	-1.1	-1.0	-1.1	-0.8	-1.2	-1.3	-0.9	-0.8	-1.0	-1.1	-1.3	-1.3	-1.2
Cholesterol lowering medication	0.6	1.0	2.7	-1.6	-1.1	-0.3	-1.1	-1.2	-1.0	-1.2	-0.5	-1.0	-1.1	-0.2	-0.5	-1.2	-1.3	-0.4	-0.2	-1.0
Heart disease (siblings)	0.6	0.7	3.1	-0.4	0.1	0.6	1.2	0.2	0.1	0.1	-1.7	-0.6	0.2	1.0	1.5	0.1	0.1	0.7	1.1	-1.1
Alzheimer’s Disease (including proxy)	0.5	0.8	2.9	-1.2	-0.9	0.1	-1.5	-1.0	-0.6	-0.9	0.3	0.1	-0.7	-0.3	-0.5	-0.9	-0.9	-0.9	-1.7	-0.7
Primary Biliary Cirrhosis	0.5	0.6	2.4	1.6	0.5	0.0	1.5	0.5	0.2	0.4	-1.3	-0.4	0.5	0.7	1.0	0.4	0.4	0.7	1.0	-0.4
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.9	0.9	-0.6	-1.1	-0.0	-0.5	-0.5	-0.6	-1.7	-1.1	-0.7	0.1	-0.1	-0.6	-0.6	-0.5	-0.5	-1.3
Neuroticism	0.5	1.2	3.5	1.5	1.9	0.5	1.3	1.1	1.4	1.1	-0.4	0.6	1.3	1.1	0.9	1.2	1.1	0.9	-0.2	0.3
Average weekly spirits intake	0.5	0.7	4.6	0.1	-0.3	-0.3	0.5	-0.1	0.0	-0.1	-2.1	-0.9	-0.1	1.3	1.0	-0.1	-0.1	0.7	-0.3	-1.6
Average weekly fortified wine intake	0.5	0.6	2.6	-0.1	0.6	0.8	-0.2	0.7	0.8	0.8	1.6	1.3	0.9	0.4	0.2	0.8	0.8	0.6	-0.2	1.0
Fed-up feelings	0.5	0.9	4.9	0.5	0.1	-1.0	0.5	-0.2	0.0	-0.3	-2.2	-1.1	-0.3	1.2	0.6	-0.2	-0.3	0.3	-1.6	-1.9
High blood pressure (mother)	0.5	0.7	3.1	-0.6	-0.5	-0.5	0.3	-0.8	-0.7	-0.9	-1.8	-1.4	-0.7	0.5	0.5	-0.9	-0.9	0.3	0.2	-1.5
Nervous feelings	0.5	0.9	2.6	1.5	-0.7	-1.6	0.2	-0.4	-0.9	-0.4	-0.6	-1.1	-0.6	-1.6	-1.3	-0.4	-0.4	-1.5	-0.3	-0.3
Worrier / anxious feelings	0.5	0.9	3.5	0.0	-0.3	-1.3	-0.8	-0.4	-0.5	-0.3	1.0	-0.2	-0.4	-1.7	-1.9	-0.3	-0.3	-1.6	-1.4	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.4	-1.6	0.4	0.8	-0.6	0.3	0.8	0.3	1.2	1.2	0.4	0.9	0.5	0.3	0.3	0.8	-0.9	0.4
Tense / ‘highly strung’	0.5	0.8	2.1	1.2	1.4	0.9	0.5	0.6	1.0	0.6	0.9	1.0	1.0	0.5	0.5	0.7	0.6	0.9	0.8	1.2
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	5.6	0.3	0.6	0.9	-0.4	0.5	0.6	0.6	2.4	1.5	0.7	-0.5	-0.4	0.6	0.6	0.0	0.2	1.8
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.5	-0.3	0.8	0.8	-0.2	0.7	1.0	0.7	1.1	1.2	0.7	0.8	0.3	0.7	0.7	0.7	-0.5	1.0
Leg fat percentage (right)	0.5	1.7	8.7	-1.0	-0.6	1.1	-0.2	-0.3	0.3	-0.4	-1.9	-0.2	-0.3	3.0	2.4	-0.5	-0.4	2.2	-0.3	-1.7
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.9	1.4	0.1	-0.0	1.3	0.6	0.1	0.6	-1.0	-0.4	0.5	0.5	0.8	0.5	0.6	0.9	1.4	-0.3
Medication: Allopurinol	0.5	0.7	1.2	-0.5	-1.1	-0.9	-0.9	-0.9	-0.8	-0.9	-0.6	-1.0	-1.0	-0.2	-0.5	-0.9	-0.9	-0.5	-0.7	-1.1
Illnesses of siblings: Diabetes	0.5	0.6	3.2	-0.5	-0.0	0.8	0.7	0.1	0.3	0.1	-1.2	0.0	0.2	1.3	1.8	0.0	0.0	1.1	0.2	-1.0
Qualifications: nursing, teaching	0.5	0.8	2.6	-1.6	0.6	1.4	-0.4	0.4	0.8	0.5	1.6	1.5	0.7	0.3	0.5	0.5	0.5	0.4	-0.2	0.9
Eye problems/disorders: Cataract	0.5	0.6	1.6	-0.2	-0.3	-1.2	-0.3	-0.7	-0.7	-0.7	-1.0	-1.3	-0.8	-0.5	-0.9	-0.7	-0.7	-0.7	-0.3	-0.8
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.2	-1.8	-0.7	0.6	-1.4	-0.7	-0.1	-0.6	0.9	0.6	-0.4	0.1	-0.0	-0.6	-0.6	-0.2	-1.3	-0.1
Leg fat percentage (left)	0.5	1.7	8.4	-0.8	-0.5	1.1	-0.0	-0.2	0.3	-0.3	-2.0	-0.2	-0.3	2.9	2.4	-0.4	-0.4	2.1	-0.3	-1.8
Ovarian Cancer	0.4	0.5	2.3	-1.1	0.6	1.3	-0.4	0.1	0.6	0.2	1.5	1.1	0.5	0.1	0.2	0.2	0.2	0.5	0.1	1.0
Mean Putamen Volume	0.4	0.5	2.1	-0.8	-0.1	-0.5	0.4	-0.5	-0.6	-0.6	-1.5	-1.1	-0.5	0.3	0.3	-0.6	-0.6	0.0	0.1	-1.4
Waist Hip Ratio (WHR)	0.4	2.0	6.7	-0.9	-0.9	-0.9	-0.4	-1.3	-0.9	-1.4	-2.6	-1.6	-1.4	0.6	0.5	-1.4	-1.4	-0.4	-2.0	-2.6
Vitamin and mineral supplements	0.4	0.5	1.0	-0.1	-0.6	-0.6	-1.0	-1.0	-0.6	-1.0	-0.2	-0.7	-0.9	-0.4	-0.7	-0.9	-1.0	-0.6	-0.8	-0.6
Pain all over the body in last month	0.4	0.4	1.9	0.7	-0.1	-0.5	1.2	0.3	-0.2	0.2	-1.4	-0.8	0.2	0.2	0.4	0.2	0.2	0.4	1.2	-0.5
Father’s age at death	0.4	0.5	3.3	-0.2	-0.2	-0.2	-0.9	-0.1	-0.1	0.1	1.8	0.6	-0.1	-1.0	-1.2	0.0	0.1	-0.8	-0.4	0.9
Number of live births	0.4	0.5	3.5	1.9	0.4	0.2	1.1	0.4	0.1	0.4	-0.3	-0.2	0.5	-0.2	0.4	0.4	0.4	0.3	1.5	0.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	9.4	-1.4	1.0	1.8	-1.2	-0.4	0.5	-0.3	3.1	1.8	0.2	-0.4	0.1	-0.2	-0.3	0.1	-0.1	1.1
Noisy workplace	0.4	0.5	2.3	0.2	-0.3	0.1	-0.8	-0.6	-0.6	-0.6	1.5	0.1	-0.4	-1.3	-0.8	-0.6	-0.6	-0.6	0.3	0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.0	-1.6	0.7	1.3	-0.6	0.5	0.9	0.5	1.7	1.7	0.6	0.6	0.3	0.6	0.5	0.5	-0.5	1.1
Pulse wave reflection index	0.4	0.5	1.2	-1.1	-1.0	-0.6	-0.4	-0.7	-0.8	-0.6	-0.3	-0.6	-0.7	-0.6	-0.3	-0.7	-0.7	-0.6	-0.5	-0.9
Medication: Paracetamol	0.4	0.6	4.3	-2.1	-0.2	0.7	-1.3	-0.4	0.1	-0.4	1.3	0.7	-0.2	0.4	0.1	-0.4	-0.4	0.5	-0.6	0.1
Migraine (self-reported)	0.4	0.6	1.9	0.0	0.8	1.4	0.1	0.6	0.9	0.6	0.6	1.2	0.7	0.8	1.0	0.6	0.6	0.8	0.0	0.5
Medication: Ibuprofen	0.4	0.5	1.2	-0.7	0.3	0.7	-0.3	0.5	0.8	0.6	1.0	1.1	0.7	0.9	0.5	0.6	0.6	1.0	-0.4	0.6
Heart disease (mother)	0.4	0.5	1.2	-0.5	-0.3	-0.1	-1.0	-0.8	-0.6	-0.8	1.0	0.0	-0.8	-1.0	-0.9	-0.7	-0.8	-1.1	-0.3	0.1
Overall health rating	0.4	0.9	2.7	0.7	0.9	0.8	1.2	0.7	0.8	0.6	-1.1	0.1	0.8	1.6	1.7	0.6	0.6	1.5	0.7	-0.4
Knee pain experienced in last month	0.4	0.7	2.8	-1.3	-0.2	1.2	-0.5	0.2	0.5	0.2	0.2	1.0	0.3	1.7	1.4	0.1	0.2	1.2	-0.6	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.9	-0.5	-0.7	-1.1	-0.8	-0.9	-0.9	-0.9	0.4	-0.6	-0.6	-0.8	-1.0	-0.9	-0.9	-0.5	-1.4	-0.7
Asthma (self-reported)	0.4	0.8	2.7	0.5	0.9	1.3	0.8	0.5	0.9	0.5	-0.6	0.5	0.8	1.5	1.6	0.5	0.5	1.5	0.3	-0.0
Impedance of whole body	0.4	2.3	6.3	2.5	1.6	-1.2	1.0	1.5	0.9	1.5	1.2	0.7	1.2	-1.5	-1.9	1.6	1.5	-1.2	-0.1	2.4
Bipolar Disorder or Schizophrenia	0.3	0.9	3.4	1.8	0.7	-0.4	1.2	1.1	0.4	1.1	0.4	0.4	0.9	-0.5	-0.4	1.0	1.1	0.0	1.1	1.3
Depressed Affect (Nagel 2018)	0.3	0.7	3.2	-0.1	0.1	-0.4	0.4	-0.1	0.2	-0.2	-1.8	-0.7	-0.1	1.4	0.9	-0.2	-0.2	0.6	-1.2	-1.6
Neuroticism (Nagel 2018)	0.3	0.6	2.1	0.1	-0.1	-1.0	-0.0	-0.6	-0.4	-0.7	-1.4	-1.1	-0.6	0.0	-0.2	-0.6	-0.6	-0.5	-1.4	-1.4
Ulcerative Colitis (UC)	0.3	0.6	2.9	1.7	0.3	-0.9	1.2	0.5	-0.1	0.4	-0.9	-0.8	0.2	-0.5	-0.3	0.4	0.4	-0.1	1.5	0.3
Lupus	0.3	0.5	1.3	-1.1	-0.3	-0.0	-1.1	-0.6	-0.3	-0.5	0.6	-0.0	-0.5	-1.0	-0.9	-0.5	-0.5	-0.9	-0.6	0.3
Blood Red Count	0.3	2.9	15.8	3.1	-1.5	-1.7	1.3	-0.2	-1.0	-0.4	-4.0	-1.9	-0.8	1.1	1.2	-0.6	-0.4	0.3	-0.8	-2.7
Blood White Count	0.3	2.2	7.8	0.6	0.9	1.8	1.5	1.0	1.3	0.9	-1.7	0.5	1.0	2.7	2.8	0.9	0.9	2.3	1.1	-0.5
Number of treatments/medications taken	0.3	0.6	1.3	-1.1	-0.9	0.3	-0.5	-0.8	-0.6	-0.9	-0.9	-0.7	-0.8	0.5	0.7	-0.9	-0.9	0.4	0.2	-1.1
Sensitivity / hurt feelings	0.3	0.6	2.6	1.4	0.1	-0.5	0.7	-0.3	-0.3	-0.4	-1.6	-1.2	-0.2	0.1	0.4	-0.3	-0.4	-0.1	-0.6	-1.4
Hearing difficulty/problems: Yes	0.3	0.4	1.3	-0.8	-0.5	0.5	-0.1	-0.1	0.0	-0.1	-1.0	-0.0	-0.0	1.1	1.1	-0.2	-0.1	0.8	-1.0	-1.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.7	0.9	0.5	-0.2	0.5	0.7	0.6	0.7	-0.1	0.4	0.6	0.5	0.1	0.7	0.7	0.6	-0.1	0.5
Medication: Co-codamol	0.3	0.3	1.1	0.5	0.5	0.1	0.7	0.5	0.5	0.4	-0.9	-0.2	0.3	1.1	0.6	0.4	0.4	0.7	0.8	-0.1
Impedance of leg (right)	0.3	1.3	5.2	1.6	0.2	-2.2	0.2	0.4	-0.1	0.4	0.1	-0.6	-0.0	-1.6	-2.3	0.5	0.4	-1.7	-1.3	0.9
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.3	-0.1	-0.2	-0.9	-0.7	-0.5	-0.5	-0.5	0.5	-0.4	-0.5	-1.0	-1.1	-0.5	-0.5	-0.9	-0.6	0.1
Medication: Levothyroxine sodium	0.3	0.5	1.1	-0.0	1.1	1.0	0.8	0.6	0.8	0.5	-0.1	0.6	0.6	0.7	1.0	0.6	0.5	0.6	0.8	0.5
Impedance of leg (left)	0.3	1.5	5.3	2.1	0.5	-2.3	0.6	0.7	-0.0	0.6	-0.0	-0.5	0.2	-1.6	-2.2	0.7	0.7	-1.7	-1.3	0.9
Medication: Ramipril	0.3	0.4	1.2	0.4	-0.3	-0.3	0.0	-0.7	-0.7	-0.8	-1.0	-1.1	-0.6	-0.4	-0.2	-0.7	-0.8	-0.3	0.4	-0.7
Gout (self-reported)	0.3	0.4	1.4	-0.6	-0.2	0.0	-0.2	-0.5	-0.1	-0.5	-1.0	-0.7	-0.5	1.0	0.6	-0.5	-0.6	0.5	-0.3	-1.2
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.7	-0.4	0.4	1.3	-0.2	0.2	0.5	0.2	0.6	0.9	0.5	0.9	0.8	0.1	0.1	1.0	0.5	0.5
Worry too long after embarrassment	0.3	0.4	2.0	0.1	-0.2	-0.8	0.1	-0.5	-0.5	-0.6	-1.4	-1.2	-0.6	0.0	-0.2	-0.6	-0.6	-0.3	-0.7	-1.1
Health satisfaction	0.3	0.4	2.4	1.0	-0.5	-0.8	0.7	0.1	-0.3	0.0	-1.5	-0.9	-0.2	0.3	0.4	-0.0	0.0	0.1	0.4	-0.7
Medication for pain relief, constipation, heartburn	0.3	0.5	1.8	1.2	-0.4	-0.7	0.9	-0.2	-0.7	-0.2	-1.4	-1.1	-0.3	-0.6	-0.0	-0.2	-0.2	-0.6	0.4	-0.9
Medication: Omeprazole	0.3	0.4	1.9	0.1	-0.1	-0.8	-0.0	-0.6	-0.3	-0.6	-1.4	-1.0	-0.6	-0.0	-0.2	-0.5	-0.6	-0.3	-0.8	-0.9
Illnesses of father: Heart disease	0.3	0.4	2.0	-0.7	-0.2	0.1	-0.1	-0.6	-0.4	-0.6	-1.0	-0.6	-0.5	0.6	0.7	-0.6	-0.6	0.2	-0.6	-1.4
Breast cancer (self-reported)	0.3	0.4	1.3	-1.1	-0.5	-0.3	-0.9	-0.5	-0.5	-0.5	0.7	0.1	-0.5	-0.5	-0.8	-0.5	-0.5	-0.6	-1.0	-0.0
Average weekly champagne plus white wine intake	0.3	0.4	1.6	-1.1	0.2	0.6	-1.0	-0.2	0.4	-0.2	1.2	0.8	-0.1	0.3	-0.3	-0.1	-0.2	0.1	-1.3	0.5
Medication: Paracetamol	0.3	0.5	1.4	-0.6	0.3	1.0	-0.4	0.4	0.7	0.4	1.2	1.0	0.5	0.7	0.6	0.4	0.4	1.0	0.4	0.8
Pain experienced in last month	0.3	0.6	1.6	0.4	-1.0	-1.2	-0.1	-0.4	-0.9	-0.5	-1.1	-1.3	-0.8	-0.5	-0.7	-0.5	-0.5	-0.6	0.4	-0.8
Worry (Nagel 2018)	0.2	0.3	0.9	0.6	0.7	-0.4	-0.2	0.2	0.4	0.2	1.0	0.6	0.3	-0.6	-0.9	0.3	0.2	-0.5	-0.7	1.0
Irritable Bowel Disease (IBD)	0.2	0.5	2.9	1.7	0.0	-0.9	0.7	0.4	-0.1	0.4	-0.3	-0.5	0.1	-0.7	-0.6	0.4	0.4	-0.4	1.2	0.5
Prostate Cancer	0.2	0.3	0.8	-0.1	-0.8	-0.7	0.1	-0.3	-0.6	-0.3	-0.9	-0.8	-0.4	-0.7	-0.3	-0.3	-0.3	-0.7	-0.1	-0.6
Rheumatoid Arthritis	0.2	0.3	0.9	-0.5	-0.4	-0.5	-0.2	-0.4	-0.4	-0.5	-0.8	-0.6	-0.5	0.3	0.0	-0.5	-0.5	0.1	-0.7	-1.0
Current tobacco smoking	0.2	0.3	0.9	-0.9	-0.0	0.8	0.1	0.0	0.2	0.0	-0.5	-0.2	0.1	0.8	0.9	-0.0	0.0	0.8	0.7	-0.5
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.0	0.3	0.8	0.9	0.5	0.6	0.5	0.6	0.6	0.6	0.7	0.2	0.4	0.6	0.6	0.6	1.4	0.8
Medication: Atenolol	0.2	0.3	1.1	-0.2	-0.2	-0.9	0.3	-0.4	-0.7	-0.4	-0.5	-1.0	-0.4	-0.7	-0.5	-0.4	-0.4	-0.5	0.0	-0.7
Chronic bronchitis/emphysema (father)	0.2	0.2	0.8	0.9	0.2	-0.4	0.7	0.5	0.3	0.5	-0.6	-0.2	0.5	0.2	0.2	0.5	0.5	0.3	-0.1	-0.1
Past tobacco smoking	0.2	0.4	0.8	-0.1	0.6	0.9	0.4	0.5	0.5	0.6	0.8	0.7	0.9	0.4	0.5	0.5	0.6	0.9	0.8	0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.3	0.3	-0.2	-0.8	0.8	-0.1	-0.4	-0.2	-1.2	-0.8	-0.0	-0.0	0.2	-0.2	-0.1	0.2	-0.2	-0.9
Mouth/teeth dental problems	0.2	0.3	0.7	-0.8	0.1	0.3	-0.5	-0.7	-0.3	-0.8	-0.3	-0.2	-0.7	-0.2	0.0	-0.7	-0.8	-0.6	-0.5	-0.3
Asthma	0.2	0.4	1.5	0.2	0.5	1.1	0.3	0.2	0.5	0.1	-0.3	0.4	0.4	1.1	1.2	0.1	0.1	1.1	0.0	-0.2
Exposure to tobacco smoke at home	0.2	0.2	1.4	-0.7	0.7	1.2	-0.4	-0.1	0.4	-0.1	0.8	0.6	0.1	0.1	0.4	0.0	-0.1	0.2	0.1	0.4
Glaucoma (self-reported)	0.2	0.2	1.4	1.0	0.4	0.4	0.5	0.2	0.1	0.2	0.1	-0.0	0.2	-0.3	0.1	0.2	0.2	-0.0	1.2	0.3
Number of children fathered	0.2	0.2	0.6	0.0	0.1	-0.3	-0.5	-0.5	-0.2	-0.5	0.2	-0.3	-0.5	-0.4	-0.8	-0.4	-0.5	-0.6	-0.6	0.1
Smoking status: Previous	0.2	0.3	1.1	0.3	-0.6	-1.0	-0.5	-0.3	-0.4	-0.3	-0.5	-0.3	-0.7	-0.3	-0.6	-0.3	-0.3	-0.9	-1.0	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.6	-1.3	0.1	-0.0	-0.7	-0.8	-0.2	-0.8	-0.3	-0.2	-0.5	-0.1	0.0	-0.7	-0.8	-0.2	-0.9	-0.7
Smoking status: Current	0.2	0.3	1.2	-0.8	0.1	1.0	0.3	0.1	0.3	0.1	-0.4	-0.0	0.2	0.9	1.1	0.1	0.1	0.9	0.8	-0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.7	-1.3	-0.0	0.6	-0.0	-0.4	-0.1	-0.4	-0.3	-0.1	-0.3	0.0	0.5	-0.4	-0.4	-0.1	0.1	-0.3
Medication: Atorvastatin	0.2	0.2	1.1	-0.4	0.3	0.3	0.0	0.4	0.6	0.3	-0.3	0.5	0.3	1.1	0.8	0.3	0.3	0.5	-0.4	-0.4
Illnesses of father: High blood pressure	0.2	0.2	0.6	-0.8	-0.5	-0.5	0.1	-0.4	-0.6	-0.4	-0.5	-0.8	-0.4	-0.7	-0.3	-0.4	-0.4	-0.4	0.1	-0.6
Fractured/broken bones in last 5 years	0.2	0.2	1.5	0.7	-0.2	-0.5	0.5	-0.0	-0.2	-0.1	-1.2	-0.9	-0.1	0.1	0.2	-0.1	-0.1	0.2	0.3	-0.7
Diastolic blood pressure, automated reading	0.2	0.7	2.0	-1.2	-0.2	0.6	0.4	-0.2	-0.0	-0.3	-1.4	-0.7	-0.1	1.2	1.3	-0.3	-0.3	1.3	1.0	-1.0
Ever depressed for a whole week	0.2	0.3	1.0	0.7	0.1	-0.4	1.0	0.4	-0.0	0.3	-0.7	-0.5	0.4	0.1	0.3	0.3	0.3	0.6	0.9	-0.0
Supplements: Calcium	0.2	0.2	0.6	0.3	0.5	0.7	0.5	0.5	0.5	0.5	-0.2	0.5	0.4	0.6	0.7	0.5	0.5	0.3	-0.3	0.0
Alcohol drinker status: Previous	0.2	0.2	0.8	-0.4	0.9	0.7	0.5	0.3	0.5	0.3	0.2	0.5	0.4	0.3	0.6	0.3	0.3	0.4	0.2	0.4
Bipolar Disorder (2018)	0.1	0.2	1.0	-0.2	0.4	0.8	0.1	-0.0	0.2	-0.0	0.4	0.2	0.3	0.3	0.6	-0.0	-0.0	0.8	1.0	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.8	-1.0	-0.2	0.2	-0.7	-0.3	-0.1	-0.2	1.3	0.3	-0.2	-1.3	-0.8	-0.2	-0.2	-0.9	0.5	0.8
Crohns Disease (2017)	0.1	0.2	0.6	0.8	-0.3	-0.6	-0.1	0.1	-0.2	0.2	0.5	0.1	-0.0	-0.7	-0.7	0.1	0.2	-0.7	0.2	0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.0	-0.8	-0.3	-0.3	-0.5	-0.2	-0.2	-0.1	0.7	0.0	-0.3	-1.0	-0.8	-0.1	-0.1	-0.8	-0.2	0.5
Breast Cancer	0.1	0.3	0.9	-0.8	0.2	0.3	0.3	-0.1	0.2	-0.2	-0.9	-0.2	0.0	0.9	1.0	-0.1	-0.2	0.8	-0.2	-0.8
Bipolar Disorder (2011)	0.1	0.1	0.4	-0.6	-0.2	-0.0	0.1	-0.4	-0.4	-0.4	-0.3	-0.5	-0.3	-0.4	0.1	-0.4	-0.4	-0.2	0.6	-0.4
HDL Cholesterol	0.1	0.2	1.0	-0.3	-0.5	-0.2	-0.9	-0.1	0.0	0.0	1.0	0.4	-0.1	-0.4	-0.8	-0.0	0.0	-0.5	-0.7	0.4
LDL Cholesterol	0.1	0.1	0.6	0.8	-0.0	0.3	0.2	-0.3	-0.3	-0.3	-0.1	-0.0	-0.1	-0.2	0.3	-0.3	-0.3	0.0	0.2	-0.1
Blood Eosinophil Count	0.1	0.4	2.2	-1.5	-0.8	0.1	-0.5	-0.6	-0.4	-0.7	-0.5	-0.4	-0.7	0.6	0.6	-0.7	-0.7	0.3	0.1	-0.9
Blood Platelet Count	0.1	1.3	5.8	-2.4	-1.1	-0.2	-1.2	-1.0	-0.4	-1.1	-1.2	-0.6	-1.0	1.2	0.5	-1.1	-1.1	0.5	-1.4	-1.5
Smoking Status	0.1	0.3	1.8	-1.4	-0.6	0.6	-0.6	-0.2	0.0	-0.2	-0.1	0.3	-0.4	0.8	0.6	-0.3	-0.2	0.2	-0.6	-0.4
Hypothyroidism (self reported)	0.1	0.3	0.8	-0.8	0.1	0.6	-0.1	-0.4	0.0	-0.4	-0.5	-0.0	-0.2	0.9	0.9	-0.4	-0.4	0.6	0.1	-0.7
Supplements: Zinc	0.1	0.1	0.5	-0.3	-0.0	0.2	-0.0	0.1	0.2	0.1	-0.3	0.2	0.0	0.7	0.4	0.1	0.1	0.6	-0.1	0.1
Diabetes (father)	0.1	0.2	0.5	0.2	0.0	0.4	0.4	0.5	0.3	0.5	0.1	0.5	0.4	0.4	0.6	0.4	0.5	0.4	0.7	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.7	0.2	0.3	0.4	-0.5	-0.4	0.0	-0.4	0.9	0.2	-0.3	-0.4	-0.2	-0.3	-0.4	-0.3	0.3	0.4
Multivitamins +/- minerals	0.1	0.1	0.3	0.1	0.0	-0.3	0.6	0.4	0.1	0.4	-0.3	-0.2	0.4	0.1	0.0	0.4	0.4	0.4	0.3	0.2
Qualifications: None of the above	0.1	0.3	1.0	1.0	0.5	0.1	0.6	0.5	0.4	0.4	-0.3	0.1	0.5	0.8	0.6	0.4	0.4	0.8	0.2	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	1.1	-0.3	0.3	-0.5	-0.2	-0.1	0.2	-0.2	-0.3	-0.2	-0.1	0.5	-0.2	-0.1	-0.1	0.2	-1.1	-0.2
Medication: Lansoprazole	0.1	0.1	0.5	-0.0	-0.3	0.1	-0.4	-0.1	0.0	-0.1	-0.4	0.0	-0.2	0.7	0.2	-0.2	-0.2	0.3	-0.4	-0.3
Lung cancer (father)	0.1	0.2	0.6	-0.2	-0.0	-0.2	0.3	0.3	0.3	0.3	-0.8	0.0	0.1	0.7	0.5	0.3	0.3	0.3	-0.8	-0.3
Birth weight of first child	0.1	0.2	0.3	-0.1	0.4	-0.2	0.3	0.6	0.5	0.5	0.4	0.5	0.6	0.3	0.1	0.5	0.6	0.5	-0.2	0.4
Qualifications: College or University degree	0.1	0.4	0.9	-0.2	0.7	0.3	0.9	0.8	0.6	0.7	-0.6	0.3	0.8	0.8	0.8	0.7	0.7	0.7	0.4	0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.1	-0.1	-0.5	0.5	0.5	0.0	0.4	-0.4	-0.2	0.3	0.3	-0.1	0.4	0.4	0.2	0.4	0.0
Long-standing illness, disability or infirmity	0.1	0.2	0.8	0.1	-0.3	-0.1	0.5	-0.3	-0.5	-0.4	-0.9	-0.6	-0.2	-0.1	0.3	-0.4	-0.4	0.2	0.6	-0.5
Medication: Aspirin	0.1	0.1	0.2	0.1	-0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.0	-0.5	-0.4	-0.2	-0.4	-0.4	-0.4	0.0	0.5	0.0
Miserableness	0.1	0.2	1.0	0.5	0.4	-0.9	0.5	0.3	0.2	0.2	-0.8	-0.3	0.3	0.4	-0.1	0.3	0.2	0.1	-1.0	-0.4
Hair Pigment	0.0	0.6	1.5	0.6	0.5	0.0	0.8	0.9	0.9	0.9	-0.6	0.4	0.9	1.2	0.7	0.9	0.9	1.2	0.1	0.2
Tanning	0.0	0.5	1.7	1.0	1.3	0.6	0.9	0.5	0.7	0.4	-0.1	0.4	0.6	0.9	0.9	0.5	0.4	0.7	-0.1	-0.0
Prospective memory result	0.0	0.0	0.2	0.1	-0.1	0.1	-0.2	0.1	0.1	0.2	0.4	0.2	0.1	0.2	-0.1	0.1	0.2	0.3	0.4	0.3
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.3	-0.2	0.3	-0.0	0.3	-0.1	0.1	-0.1	-0.5	-0.1	0.0	0.3	0.3	-0.1	-0.1	0.2	-0.0	-0.2
Medication: Aspirin	0.0	0.1	0.2	-0.2	-0.4	-0.2	-0.3	-0.2	-0.3	-0.2	0.1	-0.3	-0.2	-0.1	-0.3	-0.3	-0.2	0.1	0.4	0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.2	-0.2	-0.2	-0.1	-0.4	-0.2	-0.1	-0.2	-0.0	-0.1	-0.3	-0.0	-0.3	-0.2	-0.2	-0.3	-0.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.1	0.4	0.1	0.5	-0.2	0.1	-0.1	0.2	-0.2	-0.6	-0.2	-0.1	0.2	0.0	-0.1	-0.2	0.1	-0.3	-0.1

Hub : Genes

C11orf46

Models

Trait associations