Best TWAS P=1.84e-16 · Best GWAS P=6.22e-20 conditioned to 6.61e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Heart Left Ventricle | NOS1AP | 0.16 | 0.04 | lasso | 7 | 0.04 | 0.0038 | -8.6 | -8.2 | 1.8e-16 | 0.88 | 0.10 | 0.88 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | NOS1AP | 0.07 | 0.00 | blup | 292 | 0.00 | 0.2750 | -8.2 | -6.1 | 9.4e-10 | 0.75 | 0.04 | 0.51 | FALSE |