[Hub]/) : Traits : Heel T-Score : ← →

chr1:169,802,760-174,525,917

Best TWAS P=9.75e-17 · Best GWAS P=2.69e-47 conditioned to 1.62e-10

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FMO4	0.07	0.00	blup	610	0.02	1.7e-03	-0.99	5.6	1.8e-08	-0.04	0.31	0.15	FALSE
2	GTEx	Adipose Visceral Omentum	FMO3	0.14	0.15	lasso	3	0.13	1.9e-07	-5.78	-5.3	1.0e-07	0.10	0.91	0.01	FALSE
3	GTEx	Brain Caudate basal ganglia	DARS2	0.19	0.02	lasso	5	0.13	1.2e-04	-6.86	6.8	1.0e-11	0.02	0.07	0.66	TRUE
4	GTEx	Breast Mammary Tissue (Male)	SUCO	0.15	-0.01	lasso	1	0.01	2.3e-01	-5.52	5.2	1.9e-07	-0.10	0.04	0.05	FALSE
5	GTEx	Breast Mammary Tissue (Female)	SUCO	0.33	0.00	lasso	9	0.01	1.8e-01	-4.71	5.2	2.6e-07	-0.17	0.08	0.07	FALSE
6	GTEx	Cells Transformed fibroblasts	PIGC	0.12	0.00	enet	29	0.04	2.7e-04	10.64	-7.7	1.6e-14	0.48	0.08	0.06	TRUE
7	GTEx	Colon Transverse	SUCO	0.22	0.02	enet	30	0.08	1.7e-04	3.23	6.8	1.4e-11	-0.20	0.25	0.11	TRUE
8	GTEx	Pancreas	SUCO	0.17	0.00	enet	15	0.07	5.6e-04	-7.07	5.4	6.7e-08	-0.18	0.12	0.04	FALSE
9	GTEx	Skin Sun Exposed Lower leg	GORAB	0.07	0.01	lasso	5	0.00	4.2e-01	2.56	7.8	8.5e-15	-0.04	0.08	0.12	TRUE
10	GTEx	Skin Sun Exposed Lower leg	PIGC	0.08	0.02	lasso	5	0.02	8.8e-03	-7.74	-7.0	3.3e-12	0.22	0.52	0.03	FALSE
11	GTEx	Spleen	PIGC	0.29	0.04	lasso	6	0.07	6.6e-03	5.68	5.9	3.5e-09	-0.26	0.07	0.06	FALSE
12	GTEx	Testis	PIGC	0.25	0.17	lasso	2	0.15	4.2e-07	6.23	6.2	4.7e-10	-0.36	0.97	0.00	FALSE
13	GTEx	Thyroid	FMO3	0.13	0.05	lasso	12	0.04	9.6e-04	-5.60	-6.7	2.3e-11	0.10	0.99	0.00	FALSE
14	GTEx	Thyroid	FMO2	0.23	0.03	enet	47	0.06	2.0e-05	-3.41	-8.3	9.7e-17	0.12	0.63	0.08	TRUE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PIGC	0.02	0.03	enet	3	0.02	1.3e-03	6.15	-7.4	1.3e-13	0.35	0.09	0.16	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PIGC	0.10	0.01	blup	94	0.05	1.0e-06	4.24	-7.6	3.7e-14	0.34	0.12	0.08	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	ANKRD45	0.14	0.01	lasso	4	0.07	6.9e-08	-5.09	-6.3	3.7e-10	0.00	0.00	0.80	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	PIGC	0.09	0.00	blup	94	0.04	2.9e-05	4.08	-7.7	1.5e-14	0.28	0.05	0.31	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	PIGC	0.04	0.00	blup	94	0.01	3.2e-02	7.09	-5.9	3.1e-09	0.38	0.25	0.03	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FMO3	0.05	0.02	blup	100	0.02	8.6e-03	-6.07	-5.7	1.5e-08	0.08	0.02	0.91	FALSE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C1orf105	0.13	-0.01	blup	100	0.03	1.5e-02	-7.07	-7.0	2.9e-12	0.34	0.03	0.36	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FMO3	0.10	0.10	blup	99	0.10	4.1e-05	-4.82	-5.6	2.1e-08	0.09	0.03	0.97	FALSE
23	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PIGC	0.16	0.06	blup	94	0.07	6.9e-04	-7.96	7.8	4.8e-15	-0.26	0.01	0.93	TRUE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RC3H1	0.13	-0.01	blup	58	0.01	1.4e-01	2.50	5.6	2.4e-08	-0.07	0.01	0.29	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	DNM3	0.13	0.08	enet	29	0.10	4.9e-10	-4.79	-6.8	1.0e-11	0.36	1.00	0.00	TRUE
26	The Cancer Genome Atlas	Thyroid Carcinoma	PIGC	0.09	0.02	blup	94	0.05	5.2e-06	4.21	-6.1	1.1e-09	0.27	0.18	0.10	FALSE