[Hub]/) : Traits : Heel T-Score : ← →

chr14:91,636,395-93,268,359

Best TWAS P=2.12e-12 · Best GWAS P=3.29e-11 conditioned to 0.463

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ATXN3	0.19	0.17	lasso	5	0.17	1.7e-13	6.6	6.5	7.7e-11	1.00	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	RP11-529H20.5	0.14	0.16	lasso	3	0.15	3.0e-12	6.6	6.4	1.8e-10	0.98	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	RP11-529H20.6	0.16	0.26	lasso	2	0.26	4.8e-21	6.6	6.6	4.6e-11	1.00	0.03	0.97	FALSE
4	GTEx	Adipose Visceral Omentum	ATXN3	0.19	0.14	lasso	6	0.12	7.0e-07	6.6	6.4	1.4e-10	1.00	0.03	0.97	FALSE
5	GTEx	Adipose Visceral Omentum	RP11-529H20.5	0.19	0.05	lasso	6	0.08	9.9e-05	6.6	5.8	4.9e-09	0.94	0.03	0.97	FALSE
6	GTEx	Adipose Visceral Omentum	RP11-529H20.6	0.26	0.29	lasso	4	0.28	1.1e-14	6.5	6.6	5.0e-11	1.00	0.03	0.97	FALSE
7	GTEx	Adrenal Gland	RP11-529H20.6	0.22	0.21	lasso	7	0.18	4.8e-07	6.5	6.8	1.0e-11	0.99	0.03	0.97	FALSE
8	GTEx	Artery Aorta	TRIP11	0.20	0.00	enet	8	0.02	4.0e-02	6.6	7.0	2.1e-12	0.90	0.04	0.82	TRUE
9	GTEx	Artery Aorta	RP11-529H20.6	0.20	0.14	lasso	4	0.18	6.4e-10	6.6	5.8	8.3e-09	0.92	0.02	0.97	FALSE
10	GTEx	Artery Coronary	ATXN3	0.21	0.20	lasso	2	0.24	1.4e-08	6.6	5.6	2.6e-08	0.87	0.03	0.97	FALSE
11	GTEx	Artery Coronary	TRIP11	0.18	0.01	lasso	3	0.00	3.2e-01	6.0	6.9	4.0e-12	0.87	0.04	0.63	FALSE
12	GTEx	Artery Coronary	RP11-529H20.5	0.17	0.01	lasso	4	0.04	1.6e-02	-4.2	6.1	1.3e-09	0.71	0.05	0.73	FALSE
13	GTEx	Artery Tibial	ATXN3	0.13	0.11	lasso	3	0.10	5.8e-08	6.3	6.4	1.2e-10	0.84	0.13	0.87	FALSE
14	GTEx	Artery Tibial	RP11-529H20.6	0.20	0.22	lasso	8	0.22	2.3e-17	6.6	6.6	4.6e-11	1.00	0.02	0.98	FALSE
15	GTEx	Breast Mammary Tissue	ATXN3	0.20	0.24	lasso	8	0.23	3.5e-12	6.6	6.7	2.2e-11	1.00	0.03	0.97	FALSE
16	GTEx	Breast Mammary Tissue	RP11-529H20.5	0.22	0.10	enet	23	0.12	1.1e-06	6.6	6.0	2.6e-09	0.89	0.03	0.97	FALSE
17	GTEx	Breast Mammary Tissue	RP11-529H20.6	0.20	0.23	enet	13	0.27	3.5e-14	6.6	6.7	1.7e-11	0.99	0.03	0.97	FALSE
18	GTEx	Breast Mammary Tissue (Female)	ATXN3	0.18	0.04	lasso	4	0.03	3.3e-02	6.3	6.6	5.2e-11	0.89	0.04	0.92	FALSE
19	GTEx	Breast Mammary Tissue (Female)	RP11-529H20.5	0.17	-0.01	enet	35	-0.01	5.8e-01	6.6	5.4	8.4e-08	0.73	0.04	0.61	FALSE
20	GTEx	Breast Mammary Tissue (Female)	RP11-529H20.6	0.22	0.13	lasso	3	0.09	1.5e-03	6.6	6.8	1.5e-11	0.98	0.03	0.96	FALSE
21	GTEx	Cells EBV-transformed lymphocytes	RP11-529H20.6	0.41	0.30	lasso	2	0.28	6.9e-10	6.6	6.2	4.5e-10	0.99	0.02	0.98	FALSE
22	GTEx	Cells Transformed fibroblasts	ATXN3	0.14	0.10	lasso	9	0.09	6.0e-07	6.6	6.7	1.8e-11	0.99	0.02	0.98	FALSE
23	GTEx	Cells Transformed fibroblasts	TRIP11	0.09	0.04	lasso	2	0.00	3.8e-01	6.5	6.5	8.0e-11	0.99	0.03	0.86	FALSE
24	GTEx	Cells Transformed fibroblasts	RP11-529H20.5	0.10	0.13	lasso	11	0.12	3.1e-09	6.6	6.6	4.0e-11	1.00	0.02	0.98	FALSE
25	GTEx	Cells Transformed fibroblasts	RP11-529H20.6	0.27	0.26	lasso	6	0.24	3.1e-18	6.6	6.6	5.2e-11	1.00	0.02	0.98	FALSE
26	GTEx	Colon Sigmoid	ATXN3	0.31	0.30	lasso	2	0.33	3.4e-12	6.6	6.7	1.7e-11	0.95	0.02	0.98	FALSE
27	GTEx	Colon Sigmoid	TRIP11	0.15	0.09	enet	18	0.07	1.7e-03	4.8	5.2	1.8e-07	0.77	0.03	0.85	FALSE
28	GTEx	Colon Sigmoid	RP11-529H20.5	0.27	0.05	lasso	8	0.04	1.9e-02	6.0	6.7	2.7e-11	0.82	0.04	0.91	FALSE
29	GTEx	Colon Sigmoid	RP11-529H20.6	0.24	0.24	lasso	3	0.27	4.8e-10	6.6	6.8	1.0e-11	0.99	0.03	0.97	FALSE
30	GTEx	Colon Transverse	RP11-529H20.6	0.18	0.14	lasso	5	0.18	3.7e-09	6.6	6.4	1.2e-10	0.96	0.02	0.98	FALSE
31	GTEx	Esophagus Gastroesophageal Junction	TRIP11	0.16	0.13	lasso	11	0.12	3.7e-05	6.3	6.3	3.5e-10	0.80	0.03	0.95	FALSE
32	GTEx	Esophagus Gastroesophageal Junction	RP11-529H20.5	0.17	0.02	enet	23	0.01	9.6e-02	6.6	5.8	5.9e-09	0.81	0.03	0.92	FALSE
33	GTEx	Esophagus Gastroesophageal Junction	RP11-529H20.6	0.26	0.27	enet	26	0.26	6.2e-10	6.6	6.2	5.6e-10	0.97	0.02	0.98	FALSE
34	GTEx	Esophagus Mucosa	TRIP11	0.09	0.01	lasso	4	0.00	2.4e-01	6.0	5.3	1.0e-07	0.75	0.04	0.76	FALSE
35	GTEx	Esophagus Mucosa	RP11-529H20.6	0.13	0.11	lasso	10	0.13	7.9e-09	6.6	6.3	2.2e-10	0.96	0.03	0.97	FALSE
36	GTEx	Esophagus Muscularis	ATXN3	0.16	0.17	lasso	5	0.17	2.0e-10	6.6	6.8	1.1e-11	0.98	0.02	0.98	FALSE
37	GTEx	Esophagus Muscularis	TRIP11	0.10	0.11	lasso	4	0.10	8.3e-07	6.6	6.8	1.2e-11	0.99	0.02	0.98	FALSE
38	GTEx	Esophagus Muscularis	RP11-529H20.5	0.17	0.11	enet	19	0.11	2.9e-07	6.6	6.7	2.3e-11	0.90	0.03	0.97	FALSE
39	GTEx	Esophagus Muscularis	RP11-529H20.6	0.21	0.24	lasso	2	0.22	9.2e-14	6.6	6.6	3.6e-11	1.00	0.02	0.98	FALSE
40	GTEx	Heart Atrial Appendage	RP11-529H20.6	0.27	0.20	lasso	5	0.18	2.5e-08	6.6	6.7	1.6e-11	1.00	0.03	0.97	FALSE
41	GTEx	Heart Left Ventricle	RP11-529H20.6	0.13	0.12	enet	14	0.12	3.4e-07	6.6	5.9	3.3e-09	0.89	0.03	0.97	FALSE
42	GTEx	Lung	RP11-529H20.6	0.08	0.05	enet	15	0.05	1.8e-04	6.6	6.4	1.4e-10	0.92	0.03	0.97	FALSE
43	GTEx	Muscle Skeletal	ATXN3	0.04	0.04	lasso	5	0.04	1.2e-04	6.6	6.7	1.9e-11	0.99	0.03	0.96	FALSE
44	GTEx	Muscle Skeletal	TRIP11	0.05	0.04	lasso	6	0.03	7.9e-04	6.6	6.8	1.2e-11	0.98	0.03	0.95	FALSE
45	GTEx	Muscle Skeletal	RP11-529H20.6	0.11	0.06	lasso	2	0.06	2.9e-06	6.6	6.5	6.1e-11	0.99	0.03	0.97	FALSE
46	GTEx	Nerve Tibial	ATXN3	0.30	0.29	lasso	4	0.29	1.6e-20	6.6	6.5	7.4e-11	0.99	0.02	0.98	FALSE
47	GTEx	Nerve Tibial	TRIP11	0.21	0.14	lasso	6	0.11	3.7e-08	6.6	6.7	2.8e-11	1.00	0.02	0.98	FALSE
48	GTEx	Nerve Tibial	RP11-529H20.5	0.28	0.26	lasso	5	0.25	9.2e-18	6.6	6.6	3.4e-11	1.00	0.02	0.98	FALSE
49	GTEx	Nerve Tibial	RP11-529H20.6	0.29	0.30	lasso	4	0.29	4.4e-21	6.6	6.6	3.9e-11	1.00	0.02	0.98	FALSE
50	GTEx	Ovary	ATXN3	0.32	0.18	lasso	8	0.18	2.9e-05	6.6	6.4	1.5e-10	0.97	0.03	0.94	FALSE
51	GTEx	Ovary	RP11-529H20.5	0.24	0.10	lasso	5	0.11	1.2e-03	6.6	6.4	1.6e-10	0.96	0.03	0.88	FALSE
52	GTEx	Ovary	RP11-529H20.6	0.20	0.23	lasso	4	0.18	4.3e-05	6.6	6.5	7.6e-11	1.00	0.03	0.92	FALSE
53	GTEx	Pituitary	ATXN3	0.33	0.03	lasso	2	0.03	4.7e-02	6.6	6.4	1.2e-10	0.98	0.03	0.90	FALSE
54	GTEx	Pituitary	RP11-529H20.5	0.37	0.14	enet	7	0.07	6.3e-03	3.9	5.3	1.1e-07	0.88	0.05	0.80	FALSE
55	GTEx	Prostate	ATXN3	0.30	0.04	lasso	5	0.06	1.4e-02	6.6	5.5	3.8e-08	0.78	0.04	0.61	FALSE
56	GTEx	Prostate	RP11-529H20.6	0.28	0.00	lasso	5	0.05	2.5e-02	6.6	6.4	1.4e-10	0.82	0.03	0.81	FALSE
57	GTEx	Small Intestine Terminal Ileum	RP11-529H20.6	0.36	0.32	lasso	8	0.26	1.8e-06	6.5	6.7	2.9e-11	1.00	0.03	0.97	FALSE
58	GTEx	Spleen	ATXN3	0.27	0.03	lasso	3	0.01	1.5e-01	6.6	6.1	1.4e-09	0.94	0.03	0.81	FALSE
59	GTEx	Spleen	RP11-529H20.6	0.53	0.22	enet	40	0.32	6.2e-09	6.6	5.8	6.1e-09	0.85	0.02	0.98	FALSE
60	GTEx	Stomach	ATXN3	0.24	0.09	lasso	3	0.11	5.0e-06	6.6	6.7	2.0e-11	0.98	0.03	0.97	FALSE
61	GTEx	Stomach	RP11-529H20.6	0.20	0.27	lasso	4	0.25	2.5e-12	6.6	6.5	5.6e-11	1.00	0.02	0.98	FALSE
62	GTEx	Testis	TRIP11	0.10	0.05	lasso	4	0.02	3.5e-02	6.5	6.5	9.6e-11	1.00	0.04	0.90	FALSE
63	GTEx	Testis	RP11-529H20.5	0.19	0.05	lasso	10	0.05	4.2e-03	6.6	6.4	1.8e-10	0.96	0.03	0.96	FALSE
64	GTEx	Testis	RP11-529H20.6	0.23	0.23	lasso	3	0.22	4.9e-10	6.6	6.7	2.8e-11	0.99	0.02	0.98	FALSE
65	GTEx	Thyroid	TRIP11	0.08	0.04	lasso	4	0.02	6.3e-03	6.5	6.4	1.2e-10	0.97	0.03	0.95	FALSE
66	GTEx	Thyroid	RP11-529H20.6	0.17	0.18	lasso	2	0.17	9.6e-13	6.6	6.4	1.4e-10	1.00	0.03	0.97	FALSE
67	GTEx	Whole Blood	RP11-529H20.6	0.15	0.13	lasso	4	0.16	3.8e-14	6.6	5.8	5.1e-09	0.96	0.03	0.97	FALSE
68	YFS	Blood	ATXN3	0.20	0.14	enet	52	0.24	1.1e-75	6.6	5.2	2.3e-07	0.80	0.02	0.98	FALSE
69	YFS	Blood	FBLN5	0.79	0.51	enet	134	0.68	1.1e-315	-5.0	5.4	7.1e-08	0.35	1.00	0.00	FALSE
70	YFS	Blood	TRIP11	0.06	0.04	blup	510	0.04	4.4e-14	6.3	6.4	1.4e-10	0.85	0.09	0.91	FALSE
71	The Cancer Genome Atlas	Colon Adenocarcinoma	TRIP11	0.04	0.01	blup	70	0.01	4.4e-02	-4.2	6.4	1.5e-10	0.91	0.03	0.54	FALSE
72	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIP11	0.02	0.02	lasso	1	0.01	1.1e-02	6.6	6.6	4.7e-11	1.00	0.02	0.87	FALSE
73	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIP11	0.04	0.01	blup	71	0.02	1.4e-03	-2.3	6.5	1.1e-10	0.86	0.02	0.73	FALSE
74	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TRIP11	0.16	0.16	lasso	12	0.15	4.4e-06	6.3	5.9	4.6e-09	0.82	0.03	0.96	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	TRIP11	0.08	0.04	blup	70	0.06	3.6e-06	5.9	6.4	1.3e-10	0.77	0.11	0.88	FALSE
76	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TRIP11	0.14	0.04	blup	70	0.09	1.6e-03	4.5	6.3	3.2e-10	0.90	0.03	0.64	FALSE