Best TWAS P=3.73e-08 · Best GWAS P=2.45e-07 conditioned to 0.249
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | TMEM121 | 0.11 | 0.10 | lasso | 5 | 0.08 | 4.9e-06 | 5.2 | 5.2 | 2.5e-07 | 1.00 | 0.01 | 0.99 | FALSE |
| 2 | METSIM | Adipose | TMEM121 | 0.04 | 0.02 | bslmm | 122 | 0.01 | 2.6e-03 | 5.0 | -5.5 | 3.7e-08 | -0.82 | 0.01 | 0.98 | TRUE |