Best TWAS P=5.24e-09 · Best GWAS P=5.24e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | DDX1 | 0.10 | 0.02 | lasso | 4 | 0.02 | 0.00376 | -5.8 | 5.2 | 1.6e-07 | -0.94 | 0 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DDX1 | 0.03 | 0.04 | lasso | 1 | 0.03 | 0.00011 | -5.3 | 5.3 | 1.4e-07 | -0.96 | 0 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | DDX1 | 0.14 | 0.11 | lasso | 1 | 0.12 | 0.00028 | -5.8 | 5.8 | 5.2e-09 | -1.00 | 0 | 0.88 | TRUE |