Best TWAS P=2.84e-13 · Best GWAS P=1.45e-24 conditioned to 6.98e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | NCOA1 | 0.15 | 0.00 | enet | 15 | 0.01 | 1.4e-01 | 4.5 | 7.3 | 2.8e-13 | 0.62 | 0.04 | 0.43 | TRUE |
2 | GTEx | Nerve Tibial | KIF3C | 0.29 | 0.09 | enet | 23 | 0.15 | 1.3e-10 | 4.9 | -6.6 | 5.3e-11 | -0.01 | 0.06 | 0.93 | TRUE |
3 | The Cancer Genome Atlas | Glioblastoma Multiforme | ADCY3 | 0.36 | 0.14 | enet | 7 | 0.13 | 8.9e-05 | 3.9 | -5.2 | 1.8e-07 | -0.38 | 0.02 | 0.27 | FALSE |