[Hub]/) : Traits : Heel T-Score : ← →

chr1:18,932,744-20,503,710

Best TWAS P=3.8e-17 · Best GWAS P=1.53e-23 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CAPZB 0.13 0.16 lasso 4 0.16 1.8e-19 -7.6 7.0 2.0e-12 -0.84 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum AKR7A2 0.30 0.07 lasso 8 0.07 1.3e-04 -5.0 -5.9 2.8e-09 0.55 0.33 0.51 TRUE
3 GTEx Artery Aorta CAPZB 0.14 0.10 lasso 6 0.10 5.0e-06 -7.6 7.7 1.4e-14 -0.90 0.03 0.97 FALSE
4 GTEx Artery Coronary CAPZB 0.25 0.02 enet 22 0.03 3.3e-02 -8.8 5.7 1.0e-08 -0.65 0.06 0.37 TRUE
5 GTEx Artery Tibial CAPZB 0.09 0.07 lasso 4 0.06 8.1e-06 -9.4 7.3 2.4e-13 -0.93 0.24 0.68 TRUE
6 GTEx Liver CAPZB 0.32 0.06 lasso 7 0.13 1.6e-04 -8.8 5.8 6.7e-09 -0.62 0.05 0.52 FALSE
7 GTEx Lung CAPZB 0.12 0.00 enet 15 0.03 4.4e-03 9.4 7.7 1.6e-14 -0.57 0.04 0.88 TRUE
8 GTEx Nerve Tibial CAPZB 0.07 0.03 enet 14 0.01 3.5e-02 -8.0 8.4 3.8e-17 -0.91 0.03 0.95 TRUE
9 GTEx Skin Not Sun Exposed Suprapubic AKR7A2 0.20 0.00 lasso 5 0.04 2.4e-03 -8.3 -5.3 9.0e-08 0.53 0.04 0.77 FALSE
10 GTEx Spleen CAPZB 0.29 0.02 lasso 9 0.09 2.0e-03 -5.6 8.1 5.7e-16 -0.51 0.06 0.45 TRUE
11 GTEx Testis CAPZB 0.28 0.09 enet 18 0.09 7.8e-05 9.4 7.5 6.4e-14 -0.56 0.06 0.90 TRUE
12 GTEx Thyroid CAPZB 0.22 0.06 lasso 8 0.15 1.1e-11 -6.8 8.0 9.2e-16 -0.78 0.45 0.55 TRUE
13 ROSMAP Brain Pre-frontal Cortex CAPZB 0.28 0.39 lasso 4 0.38 9.4e-52 -7.8 7.9 2.6e-15 -0.87 1.00 0.00 TRUE
14 YFS Blood CAPZB 0.06 0.10 bslmm 534 0.09 5.1e-29 -7.8 7.4 1.1e-13 -0.85 0.92 0.08 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma CAPZB 0.08 0.06 blup 160 0.07 1.2e-07 -9.4 7.8 7.0e-15 -0.88 0.03 0.97 FALSE