[Hub]/) : Traits : Heel T-Score : ← →

chr1:15,119,708-17,659,556

Best TWAS P=3.55e-28 · Best GWAS P=3.57e-31 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CASP9	0.09	0.07	lasso	2	0.07	2.3e-09	-5.22	-5.5	4.9e-08	-0.06	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CASP9	0.11	0.12	enet	17	0.11	2.9e-09	-5.21	5.2	2.0e-07	0.09	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	DNAJC16	0.19	0.03	enet	41	0.06	3.9e-04	-5.20	8.7	5.0e-18	0.27	0.26	0.12	TRUE
4	GTEx	Adipose Visceral Omentum	RSG1	0.10	0.10	enet	6	0.10	1.1e-05	4.93	5.4	6.7e-08	0.02	0.49	0.03	FALSE
5	GTEx	Adipose Visceral Omentum	CASP9	0.10	0.05	lasso	11	0.05	8.9e-04	11.03	11.0	3.5e-28	0.24	0.46	0.24	TRUE
6	GTEx	Artery Tibial	RP11-169K16.9	0.08	0.01	enet	24	0.01	3.2e-02	0.12	-6.7	2.6e-11	-0.37	0.09	0.31	TRUE
7	GTEx	Breast Mammary Tissue	CASP9	0.14	0.15	lasso	11	0.14	7.2e-08	-5.20	5.2	1.9e-07	0.08	0.99	0.00	TRUE
8	GTEx	Esophagus Mucosa	RP11-288I21.1	0.08	0.02	enet	25	0.03	3.9e-03	5.50	-5.4	7.8e-08	-0.19	0.30	0.03	FALSE
9	GTEx	Esophagus Muscularis	CASP9	0.16	0.15	lasso	5	0.14	6.7e-09	-5.22	5.2	1.8e-07	0.08	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	FBLIM1	0.08	0.02	lasso	2	0.01	7.8e-02	8.67	8.3	1.2e-16	0.23	0.11	0.28	FALSE
11	GTEx	Heart Atrial Appendage	CASP9	0.25	0.21	enet	16	0.25	2.1e-11	-5.20	5.4	7.7e-08	0.09	1.00	0.00	FALSE
12	GTEx	Muscle Skeletal	RP11-169K16.9	0.09	0.03	enet	11	0.04	1.0e-04	11.03	-9.4	4.1e-21	-0.81	0.08	0.89	TRUE
13	GTEx	Nerve Tibial	CASP9	0.09	0.09	lasso	12	0.03	1.6e-03	-5.20	5.3	1.1e-07	0.08	0.94	0.00	FALSE
14	GTEx	Ovary	CASP9	0.33	0.07	lasso	7	0.06	1.4e-02	-5.21	5.8	6.1e-09	0.14	0.18	0.05	TRUE
15	GTEx	Pancreas	RP4-798A10.2	0.18	0.01	lasso	6	0.06	1.8e-03	4.34	5.3	9.3e-08	0.36	0.06	0.49	FALSE
16	GTEx	Pituitary	ARHGEF19	0.30	0.11	lasso	14	0.11	8.7e-04	-2.56	6.3	2.5e-10	0.06	0.09	0.06	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	ARHGEF19	0.10	0.11	lasso	4	0.10	4.2e-06	5.09	-5.1	3.1e-07	0.01	0.91	0.00	TRUE
18	GTEx	Stomach	CASP9	0.24	0.06	enet	14	0.11	9.4e-06	-5.21	6.4	1.3e-10	0.11	0.96	0.00	FALSE
19	GTEx	Uterus	CASP9	0.48	0.19	lasso	7	0.22	2.5e-05	-5.21	5.4	5.7e-08	0.10	0.48	0.06	FALSE
20	GTEx	Whole Blood	CROCCP2	0.15	0.01	enet	14	0.06	1.3e-06	4.84	-5.8	7.2e-09	0.04	0.04	0.75	TRUE
21	ROSMAP	Brain Pre-frontal Cortex	PLEKHM2	0.06	0.01	blup	488	0.03	4.7e-05	5.51	5.5	4.9e-08	0.09	0.31	0.03	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	DDI2	0.09	0.02	bslmm	491	0.04	5.9e-06	4.30	8.0	1.3e-15	0.37	0.67	0.04	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZBTB17	0.02	0.00	blup	69	0.01	5.0e-04	-1.60	-7.7	1.1e-14	-0.72	0.03	0.52	TRUE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	CLCNKA	0.06	0.02	blup	62	0.03	9.8e-03	3.75	-6.4	1.7e-10	-0.51	0.04	0.18	TRUE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1orf89	0.03	0.03	enet	6	0.03	2.2e-04	4.84	5.1	2.8e-07	-0.01	0.02	0.92	FALSE
26	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1orf89	0.06	0.04	blup	44	0.04	3.3e-03	4.48	5.2	1.6e-07	0.02	0.05	0.57	FALSE
27	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1orf89	0.10	0.07	blup	43	0.11	5.2e-06	4.50	5.7	1.1e-08	0.01	0.02	0.97	TRUE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	CLCNKA	0.22	0.28	lasso	10	0.28	7.8e-30	4.34	-5.2	1.5e-07	-0.45	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	CLCNKB	0.03	0.03	lasso	2	0.01	1.1e-02	-4.96	-5.6	2.6e-08	-0.32	0.02	0.54	FALSE
30	The Cancer Genome Atlas	Soft Tissue Sarcoma	SPEN	0.09	0.02	blup	72	0.02	2.5e-02	-2.35	-7.5	4.5e-14	-0.61	0.03	0.10	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	HSPB7	0.34	0.42	enet	15	0.46	6.7e-49	4.12	5.7	9.5e-09	0.54	1.00	0.00	FALSE