Best TWAS P=3.03e-09 · Best GWAS P=1.27e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | TCF7L1 | 0.39 | 0.21 | lasso | 7 | 0.20 | 3.7e-11 | -6.4 | -5.9 | 3.0e-09 | 0.97 | 0.00 | 1.00 | TRUE |
2 | GTEx | Artery Tibial | TCF7L1 | 0.15 | 0.04 | enet | 6 | 0.03 | 2.6e-03 | 4.7 | -5.5 | 4.6e-08 | 0.92 | 0.01 | 0.99 | FALSE |