[Hub]/) : Traits : Heel T-Score : ← →

chr2:70,715,824-72,622,480

Best TWAS P=2.83e-15 · Best GWAS P=7.02e-20 conditioned to 2.79e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ZNF638 0.25 0.07 enet 20 0.10 5.2e-06 -8.0 -7.9 2.8e-15 -0.06 0.01 0.99 TRUE
2 GTEx Artery Aorta PAIP2B 0.09 0.02 lasso 3 0.02 3.0e-02 -5.2 -5.6 1.9e-08 -0.04 0.28 0.04 TRUE
3 GTEx Artery Tibial ZNF638 0.10 0.06 enet 13 0.07 2.4e-06 -7.9 -7.4 1.1e-13 -0.02 0.01 0.99 TRUE
4 GTEx Esophagus Muscularis PAIP2B 0.16 0.07 lasso 6 0.03 3.5e-03 -5.4 -5.4 7.6e-08 0.00 0.56 0.02 FALSE
5 GTEx Lung PAIP2B 0.10 0.07 lasso 8 0.06 1.7e-05 -5.2 -5.2 2.1e-07 -0.01 0.95 0.00 FALSE
6 GTEx Nerve Tibial PAIP2B 0.11 0.08 lasso 7 0.07 5.5e-06 -5.2 -5.2 1.9e-07 -0.01 0.93 0.02 FALSE
7 GTEx Skin Sun Exposed Lower leg PAIP2B 0.14 0.07 enet 39 0.07 3.0e-06 -6.4 -5.3 1.4e-07 -0.08 0.32 0.65 FALSE
8 GTEx Thyroid PAIP2B 0.11 0.06 lasso 4 0.04 5.4e-04 -5.2 -5.5 3.4e-08 -0.02 0.42 0.27 FALSE
9 METSIM Adipose PAIP2B 0.05 0.03 lasso 9 0.03 5.0e-05 -6.4 -6.2 6.6e-10 -0.03 0.61 0.32 TRUE
10 YFS Blood DYSF 0.02 0.01 blup 563 0.01 1.1e-03 -4.1 -5.2 1.8e-07 0.02 0.22 0.03 TRUE
11 The Cancer Genome Atlas Esophageal Carcinoma ZNF638 0.12 0.08 lasso 1 0.07 2.2e-03 -6.7 -6.7 2.6e-11 -0.05 0.05 0.65 FALSE
12 The Cancer Genome Atlas Glioblastoma Multiforme CYP26B1 0.19 0.01 lasso 4 0.00 3.6e-01 5.5 5.9 4.1e-09 -0.02 0.04 0.05 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma ZNF638 0.08 0.05 enet 10 0.05 5.6e-06 -8.0 -7.2 6.9e-13 -0.04 0.01 0.99 FALSE