[Hub]/) : Traits : Heel T-Score : ← →

chr2:95,778,365-97,683,329

Best TWAS P=8.78e-09 · Best GWAS P=1.64e-08 conditioned to 0.417

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	GPAT2	0.04	0.03	enet	12	0.03	2.6e-03	5.6	5.5	5.2e-08	0.88	0.02	0.96	FALSE
2	GTEx	Adipose Subcutaneous	FAHD2CP	0.16	0.08	lasso	6	0.10	1.7e-08	5.6	5.3	9.6e-08	0.93	0.01	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	GPAT2	0.06	0.02	lasso	6	0.02	2.9e-02	4.8	5.3	9.9e-08	0.83	0.04	0.72	FALSE
4	GTEx	Adipose Visceral Omentum	ADRA2B	0.10	0.04	lasso	3	0.01	8.0e-02	5.5	5.7	1.4e-08	0.93	0.02	0.90	FALSE
5	GTEx	Adipose Visceral Omentum	FAHD2CP	0.09	0.07	lasso	5	0.06	4.0e-04	4.9	5.3	1.2e-07	0.84	0.04	0.88	FALSE
6	GTEx	Adrenal Gland	GPAT2	0.07	0.05	lasso	4	0.02	6.7e-02	5.2	5.5	3.9e-08	0.95	0.03	0.72	FALSE
7	GTEx	Brain Frontal Cortex BA9	ITPRIPL1	0.12	0.05	lasso	3	0.03	5.1e-02	5.6	5.3	1.3e-07	0.97	0.02	0.74	FALSE
8	GTEx	Cells Transformed fibroblasts	ITPRIPL1	0.05	0.06	lasso	6	0.02	1.5e-02	5.0	5.1	2.8e-07	0.91	0.03	0.94	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	ADRA2B	0.12	0.07	enet	10	0.09	4.4e-04	4.6	5.7	1.6e-08	0.92	0.04	0.88	FALSE
10	GTEx	Heart Left Ventricle	GPAT2	0.08	0.12	enet	7	0.10	7.3e-06	5.0	5.2	2.4e-07	0.97	0.04	0.96	FALSE
11	GTEx	Heart Left Ventricle	FAHD2CP	0.10	0.02	lasso	4	0.03	7.6e-03	4.8	5.1	2.9e-07	0.78	0.06	0.71	FALSE
12	GTEx	Liver	LINC00342	0.12	0.03	enet	13	0.06	8.5e-03	5.6	5.2	1.8e-07	0.86	0.02	0.75	FALSE
13	GTEx	Lung	GPAT2	0.04	0.03	lasso	2	0.02	5.8e-03	5.6	5.5	3.1e-08	0.99	0.02	0.91	FALSE
14	GTEx	Lung	FAHD2CP	0.09	0.10	lasso	5	0.10	4.3e-08	4.6	5.4	8.3e-08	0.94	0.03	0.97	FALSE
15	GTEx	Muscle Skeletal	GPAT2	0.13	0.14	enet	11	0.16	1.1e-15	5.3	5.2	1.7e-07	0.93	0.04	0.96	FALSE
16	GTEx	Muscle Skeletal	FAHD2CP	0.07	0.08	lasso	5	0.08	2.5e-08	5.6	5.4	5.6e-08	0.99	0.01	0.99	FALSE
17	GTEx	Nerve Tibial	LINC00342	0.06	0.05	lasso	4	0.04	7.0e-04	5.5	5.4	6.1e-08	0.90	0.02	0.98	FALSE
18	GTEx	Pancreas	ANKRD36C	0.05	0.05	lasso	4	0.03	1.5e-02	5.2	5.1	3.1e-07	0.96	0.03	0.66	FALSE
19	GTEx	Pancreas	FAHD2CP	0.10	0.15	lasso	3	0.13	5.2e-06	5.6	5.5	3.9e-08	0.99	0.02	0.98	FALSE
20	GTEx	Skin Sun Exposed Lower leg	TMEM127	0.03	0.04	lasso	3	0.03	1.3e-03	5.5	5.3	9.3e-08	0.83	0.02	0.94	FALSE
21	GTEx	Small Intestine Terminal Ileum	TMEM127	0.27	0.23	lasso	5	0.22	1.0e-05	5.5	5.4	6.5e-08	0.85	0.02	0.91	FALSE
22	GTEx	Spleen	FAHD2CP	0.18	0.18	lasso	7	0.16	6.4e-05	5.3	5.4	7.1e-08	0.96	0.03	0.92	FALSE
23	GTEx	Testis	FAHD2CP	0.14	0.23	lasso	7	0.24	6.8e-11	4.6	5.4	7.1e-08	0.95	0.03	0.97	FALSE
24	GTEx	Thyroid	ADRA2B	0.07	0.11	enet	13	0.10	2.4e-08	5.3	5.8	8.8e-09	0.93	0.03	0.97	TRUE
25	METSIM	Adipose	GPAT2	0.01	0.01	blup	119	0.01	4.4e-02	5.5	5.3	9.1e-08	0.91	0.03	0.89	FALSE
26	YFS	Blood	TMEM127	0.03	0.04	enet	6	0.04	1.5e-13	4.6	5.3	1.3e-07	0.93	0.04	0.96	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC285033	0.32	0.07	enet	7	0.12	3.5e-07	5.3	5.3	1.3e-07	0.71	0.00	0.88	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM127	0.06	0.05	lasso	1	0.05	3.8e-06	5.3	5.3	8.8e-08	0.83	0.00	0.99	FALSE