[Hub]/) : Traits : Heel T-Score :

chr2:127,927,990-129,652,948

Best TWAS P=2.91e-11 · Best GWAS P=7.36e-11 conditioned to 0.279

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous UGGT1 0.07 0.05 lasso 3 0.06 1.7e-05 -6.5 6.5 7.4e-11 -1.00 0.01 0.99 FALSE
2 GTEx Artery Aorta UGGT1 0.16 0.16 lasso 3 0.17 1.1e-09 -6.5 6.6 3.7e-11 -0.98 0.01 0.99 FALSE
3 GTEx Cells Transformed fibroblasts UGGT1 0.13 0.13 lasso 3 0.12 2.3e-09 -6.4 6.5 9.9e-11 -0.98 0.01 0.99 FALSE
4 GTEx Cells Transformed fibroblasts AMMECR1L 0.08 0.00 enet 17 0.00 1.6e-01 -3.8 -5.3 8.8e-08 0.50 0.05 0.55 FALSE
5 GTEx Esophagus Muscularis UGGT1 0.12 0.13 lasso 7 0.13 2.7e-08 -6.5 6.5 7.4e-11 -1.00 0.01 0.99 FALSE
6 GTEx Nerve Tibial UGGT1 0.18 0.15 enet 18 0.13 1.6e-09 -6.5 5.8 8.6e-09 -0.91 0.01 0.99 FALSE
7 GTEx Skin Sun Exposed Lower leg UGGT1 0.07 0.07 lasso 5 0.05 6.3e-05 -6.5 6.4 1.5e-10 -1.00 0.01 0.99 FALSE
8 METSIM Adipose UGGT1 0.10 0.10 enet 17 0.10 2.5e-14 -6.4 5.3 9.4e-08 -0.93 0.01 0.99 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma UGGT1 0.02 0.02 blup 65 0.02 2.5e-04 -5.8 5.3 1.2e-07 -0.89 0.02 0.88 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma UGGT1 0.06 0.02 enet 7 0.04 1.7e-05 -4.4 5.6 1.8e-08 -0.76 0.05 0.89 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma UGGT1 0.04 0.03 blup 65 0.02 9.4e-04 -4.5 6.1 8.8e-10 -0.74 0.03 0.48 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma UGGT1 0.04 0.00 blup 65 0.02 8.6e-03 -6.4 6.7 2.9e-11 -0.91 0.01 0.80 TRUE