[Hub]/) : Traits : Heel T-Score : ← →

chr2:117,881,707-120,718,322

Best TWAS P=3.13e-28 · Best GWAS P=7.89e-192 conditioned to 0

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CCDC93	0.04	0.00	blup	511	0.03	3.1e-04	7.34	7.6	2.4e-14	0.03	0.77	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	DDX18	0.30	0.34	lasso	11	0.38	2.7e-49	5.32	-5.9	2.9e-09	-0.01	1.00	0.00	FALSE
3	GTEx	Artery Aorta	AC009404.2	0.15	0.10	lasso	2	0.07	7.2e-05	-5.02	5.4	6.4e-08	0.02	0.46	0.03	FALSE
4	GTEx	Cells Transformed fibroblasts	DDX18	0.10	0.05	enet	19	0.06	5.7e-05	-1.65	-6.2	6.8e-10	-0.12	0.23	0.08	TRUE
5	GTEx	Esophagus Mucosa	INSIG2	0.09	0.00	lasso	4	0.00	5.2e-01	9.68	-9.4	3.9e-21	-0.08	0.21	0.04	FALSE
6	GTEx	Heart Atrial Appendage	HTR5BP	0.22	0.09	lasso	5	0.08	1.6e-04	-0.75	-5.7	1.2e-08	-0.12	0.51	0.05	TRUE
7	GTEx	Liver	INSIG2	0.26	0.00	lasso	3	0.00	2.3e-01	-4.92	-11.0	3.1e-28	-0.10	0.06	0.12	TRUE
8	GTEx	Liver	AC009404.2	0.23	0.20	lasso	2	0.20	3.6e-06	-5.02	5.5	4.4e-08	0.05	0.12	0.07	FALSE
9	GTEx	Lung	STEAP3	0.13	0.00	enet	18	0.01	4.0e-02	-2.78	-5.9	3.6e-09	0.00	0.16	0.05	TRUE
10	GTEx	Nerve Tibial	DDX18	0.19	0.03	lasso	7	0.06	2.9e-05	4.72	-6.3	3.9e-10	0.01	0.21	0.04	FALSE
11	GTEx	Nerve Tibial	INSIG2	0.13	0.05	lasso	5	0.02	7.0e-03	-6.71	-6.5	9.2e-11	-0.07	0.35	0.15	TRUE
12	GTEx	Skin Sun Exposed Lower leg	STEAP3-AS1	0.14	0.05	enet	14	0.08	6.6e-07	-1.21	7.9	2.2e-15	0.01	0.55	0.34	TRUE
13	GTEx	Skin Sun Exposed Lower leg	AC009404.2	0.10	0.12	lasso	2	0.09	4.8e-08	-5.02	5.2	2.1e-07	0.04	1.00	0.00	FALSE
14	GTEx	Whole Blood	INSIG2	0.07	0.06	lasso	4	0.04	9.4e-05	9.69	-10.1	3.8e-24	-0.08	0.78	0.01	TRUE
15	METSIM	Adipose	INSIG2	0.07	0.03	enet	26	0.04	6.6e-07	-4.50	-5.8	6.4e-09	-0.07	0.91	0.00	FALSE
16	METSIM	Adipose	MARCO	0.22	0.16	lasso	5	0.20	1.7e-29	-6.18	5.7	1.1e-08	0.09	1.00	0.00	FALSE
17	NTR	Blood	DDX18	0.03	0.00	bslmm	472	0.00	1.3e-01	4.68	-8.4	3.1e-17	-0.19	0.09	0.09	FALSE
18	NTR	Blood	MARCO	0.24	0.18	enet	18	0.19	6.3e-59	-6.18	5.6	1.8e-08	0.07	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	INSIG2	0.03	0.01	lasso	3	0.01	2.2e-02	9.34	-10.5	1.2e-25	-0.03	0.01	0.25	TRUE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	MARCO	0.07	0.03	blup	60	0.05	4.6e-10	-6.18	6.5	7.1e-11	0.04	1.00	0.00	FALSE
21	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DDX18	0.07	0.06	lasso	3	0.04	4.9e-03	-4.92	-5.3	1.4e-07	0.04	0.02	0.25	TRUE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	INSIG2	0.04	0.01	blup	74	0.03	1.3e-04	10.48	-8.3	8.5e-17	-0.13	0.21	0.26	TRUE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MARCO	0.04	0.00	blup	60	0.02	3.5e-03	-6.18	7.8	4.4e-15	0.02	0.02	0.45	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MARCO	0.06	0.07	lasso	2	0.07	2.9e-08	-6.18	6.1	1.3e-09	0.06	0.99	0.00	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MARCO	0.20	0.08	lasso	3	0.11	9.7e-07	-6.18	5.5	3.3e-08	0.07	0.97	0.00	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	MARCO	0.06	0.03	blup	60	0.04	1.6e-05	-6.18	7.3	2.8e-13	0.01	0.25	0.62	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MARCO	0.05	0.04	lasso	1	0.03	4.5e-04	-6.18	6.2	6.3e-10	0.06	0.59	0.01	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MARCO	0.13	0.02	blup	61	0.04	7.5e-04	-6.18	8.2	3.6e-16	0.03	0.05	0.31	TRUE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	INSIG2	0.16	0.05	blup	74	0.12	2.7e-12	8.47	-10.6	1.8e-26	0.05	0.26	0.74	TRUE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	MARCO	0.08	0.06	lasso	3	0.06	1.0e-06	-4.70	5.4	5.5e-08	0.10	0.96	0.01	FALSE
31	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MARCO	0.25	0.18	lasso	4	0.18	7.4e-07	-6.18	5.3	1.1e-07	0.06	0.29	0.08	FALSE