[Hub]/) : Traits : Heel T-Score :

chr2:152,280,365-154,267,276

Best TWAS P=1.32e-15 · Best GWAS P=3.7e-18 conditioned to 0.00714

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRPF40A 0.16 0.18 bslmm 464 0.19 1.9e-22 -7.14 -8.0 1.3e-15 0.17 0.99 0.01 TRUE
2 GTEx Artery Coronary STAM2 0.13 0.04 lasso 6 0.01 1.7e-01 -5.17 -6.7 3.0e-11 0.74 0.02 0.84 FALSE
3 GTEx Breast Mammary Tissue STAM2 0.24 0.07 lasso 2 0.04 2.4e-03 -6.49 -6.1 1.2e-09 0.44 0.42 0.04 FALSE
4 GTEx Breast Mammary Tissue (Male) STAM2 0.20 -0.01 enet 9 -0.01 7.1e-01 -6.55 -7.4 9.8e-14 0.63 0.06 0.34 TRUE
5 GTEx Nerve Tibial STAM2 0.07 0.03 lasso 4 0.02 9.2e-03 -5.17 -5.6 1.8e-08 0.52 0.25 0.38 FALSE
6 METSIM Adipose STAM2 0.05 0.02 bslmm 429 0.02 4.2e-04 2.91 -5.1 2.9e-07 0.44 0.71 0.04 FALSE
7 YFS Blood STAM2 0.03 0.01 blup 425 0.02 3.9e-07 0.93 -6.1 1.1e-09 0.42 0.95 0.01 TRUE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma PRPF40A 0.06 0.00 blup 66 0.04 9.3e-03 -7.14 -6.7 2.9e-11 0.08 0.02 0.69 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma PRPF40A 0.03 0.02 blup 66 0.02 5.2e-03 -7.19 -7.2 5.9e-13 0.12 0.01 0.78 FALSE