[Hub]/) : Traits : Heel T-Score : ← →

chr2:171,683,107-173,114,238

Best TWAS P=2.36e-11 · Best GWAS P=4.15e-13 conditioned to 0.000384

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CYBRD1 0.35 0.19 lasso 6 0.24 7.3e-20 6.7 -6.5 6.6e-11 -0.77 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum CYBRD1 0.33 0.10 lasso 10 0.26 4.6e-14 3.7 -6.6 3.9e-11 -0.71 0.03 0.97 FALSE
3 GTEx Artery Tibial CYBRD1 0.37 0.08 lasso 9 0.21 3.0e-16 4.7 -5.8 5.7e-09 -0.75 0.00 1.00 FALSE
4 GTEx Breast Mammary Tissue CYBRD1 0.32 0.21 enet 16 0.27 2.0e-14 6.7 -5.9 4.4e-09 -0.74 0.00 1.00 FALSE
5 GTEx Breast Mammary Tissue (Male) CYBRD1 0.35 0.24 lasso 6 0.20 2.4e-05 6.7 -6.0 2.0e-09 -0.72 0.00 0.98 FALSE
6 GTEx Breast Mammary Tissue (Female) CYBRD1 0.20 0.07 lasso 2 0.14 4.5e-05 6.7 -6.5 9.1e-11 -0.78 0.00 0.98 FALSE
7 GTEx Esophagus Muscularis CYBRD1 0.33 0.07 lasso 9 0.22 1.3e-13 4.7 -5.7 1.0e-08 -0.75 0.06 0.94 FALSE
8 GTEx Muscle Skeletal CYBRD1 0.10 0.00 enet 9 0.01 1.5e-02 6.7 -6.7 2.4e-11 -0.71 0.00 0.99 TRUE
9 GTEx Nerve Tibial CYBRD1 0.36 0.07 lasso 10 0.20 2.3e-14 6.7 -6.0 2.1e-09 -0.73 0.00 1.00 FALSE
10 GTEx Thyroid CYBRD1 0.26 0.08 enet 26 0.12 1.4e-09 6.7 -5.9 3.1e-09 -0.72 0.00 1.00 FALSE
11 METSIM Adipose CYBRD1 0.08 0.06 lasso 6 0.06 8.0e-09 -4.0 -5.5 3.7e-08 -0.48 0.92 0.07 FALSE
12 ROSMAP Brain Pre-frontal Cortex CYBRD1 0.37 0.16 lasso 9 0.30 3.0e-39 5.1 -5.9 3.4e-09 -0.77 0.31 0.69 FALSE
13 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CYBRD1 0.14 0.04 enet 12 0.09 2.2e-05 7.3 5.2 2.0e-07 0.78 0.00 0.96 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma CYBRD1 0.10 0.06 lasso 4 0.06 6.2e-07 6.7 -6.6 3.3e-11 -0.86 0.00 1.00 FALSE