[Hub]/) : Traits : Heel T-Score :

chr3:98,838,914-102,090,888

Best TWAS P=8.15e-13 · Best GWAS P=3.81e-13 conditioned to 0.000817

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CMSS1 0.12 0.01 enet 15 0.06 2.8e-04 1.7 -6.0 2.3e-09 -0.05 0.05 0.80 TRUE
2 GTEx Adipose Visceral Omentum ZBTB11-AS1 0.13 0.02 lasso 3 0.03 1.5e-02 7.2 -5.8 5.2e-09 -0.42 0.02 0.93 FALSE
3 GTEx Artery Aorta ZBTB11-AS1 0.19 0.13 lasso 6 0.12 5.3e-07 6.2 -6.8 1.4e-11 -0.54 0.03 0.97 FALSE
4 GTEx Artery Tibial ZBTB11-AS1 0.19 0.13 enet 14 0.14 7.7e-11 6.2 -5.6 2.1e-08 -0.43 0.80 0.20 FALSE
5 GTEx Brain Cortex TRMT10C 0.18 0.01 enet 23 0.02 6.9e-02 -2.9 -5.3 9.0e-08 -0.47 0.05 0.29 FALSE
6 GTEx Cells EBV-transformed lymphocytes SENP7 0.30 0.08 enet 40 0.22 9.2e-08 -3.0 5.7 1.4e-08 0.82 0.11 0.89 FALSE
7 GTEx Esophagus Muscularis ZBTB11-AS1 0.16 0.10 lasso 5 0.10 7.2e-07 7.2 -7.2 8.1e-13 -0.60 0.02 0.98 TRUE
8 GTEx Heart Atrial Appendage ZBTB11-AS1 0.10 0.08 enet 10 0.05 2.1e-03 -4.7 -5.6 2.3e-08 -0.48 0.24 0.22 FALSE
9 GTEx Liver RP11-234A1.1 0.25 0.00 enet 4 0.00 2.4e-01 7.2 -6.8 1.5e-11 -0.63 0.03 0.36 FALSE
10 GTEx Nerve Tibial SENP7 0.20 0.17 lasso 5 0.18 2.0e-12 -3.8 5.7 1.2e-08 0.75 0.69 0.31 FALSE
11 GTEx Nerve Tibial ZBTB11-AS1 0.21 0.18 lasso 3 0.18 7.9e-13 6.2 -6.8 1.3e-11 -0.57 0.91 0.09 FALSE
12 GTEx Spleen SENP7 0.25 0.09 enet 43 0.09 3.3e-03 4.8 5.9 3.5e-09 0.79 0.06 0.85 FALSE
13 GTEx Spleen ZBTB11-AS1 0.27 0.17 lasso 3 0.11 8.2e-04 6.1 -5.9 4.4e-09 -0.47 0.07 0.09 FALSE
14 GTEx Whole Blood SENP7 0.10 0.06 enet 42 0.06 7.3e-06 7.2 6.0 1.9e-09 0.87 0.02 0.98 FALSE
15 METSIM Adipose SENP7 0.05 0.05 blup 478 0.07 2.5e-10 -3.0 6.1 1.2e-09 0.75 0.13 0.87 FALSE
16 YFS Blood PCNP 0.02 0.01 lasso 4 0.01 3.4e-05 7.2 -6.7 2.0e-11 -0.59 0.02 0.98 FALSE
17 The Cancer Genome Atlas Bladder Urothelial Carcinoma SENP7 0.07 0.04 enet 17 0.07 9.3e-07 -5.6 5.4 7.4e-08 0.78 0.04 0.94 FALSE
18 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LOC100009676 0.18 0.05 blup 26 0.07 3.2e-04 6.1 -6.0 1.8e-09 -0.47 0.00 0.70 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC100009676 0.06 0.04 enet 18 0.03 1.1e-04 6.2 -5.5 3.2e-08 -0.47 0.00 0.99 FALSE
20 The Cancer Genome Atlas Lung Adenocarcinoma LOC100009676 0.06 0.00 blup 26 0.02 5.7e-03 6.2 -5.9 3.8e-09 -0.45 0.00 0.75 FALSE
21 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC100009676 0.11 0.09 lasso 2 0.06 1.8e-03 6.1 -6.1 1.4e-09 -0.52 0.00 0.92 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma LOC100009676 0.13 0.07 blup 26 0.09 6.5e-09 6.2 -5.1 2.7e-07 -0.47 0.00 1.00 FALSE