[Hub]/) : Traits : Heel T-Score : ← →

chr3:125,462,329-126,888,966

Best TWAS P=2.17e-10 · Best GWAS P=3.1e-10 conditioned to 0.0792

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZXDC	0.08	0.04	lasso	4	0.05	3.2e-07	4.4	-5.7	1.4e-08	0.78	0.15	0.84	FALSE
2	GTEx	Adipose Subcutaneous	ZXDC	0.13	0.06	enet	6	0.05	6.4e-05	-5.9	5.5	4.4e-08	-0.83	0.03	0.96	FALSE
3	GTEx	Artery Tibial	ZXDC	0.16	0.14	lasso	5	0.14	3.0e-11	-6.0	6.0	2.4e-09	-0.86	0.02	0.98	FALSE
4	GTEx	Brain Cerebellum	ZXDC	0.24	0.16	lasso	4	0.13	1.0e-04	-5.9	6.1	1.2e-09	-0.87	0.02	0.95	FALSE
5	GTEx	Brain Frontal Cortex BA9	ZXDC	0.37	0.08	enet	20	0.18	1.3e-05	3.9	5.8	7.7e-09	-0.75	0.03	0.91	FALSE
6	GTEx	Breast Mammary Tissue	ZXDC	0.19	0.16	lasso	6	0.16	1.6e-08	-5.9	6.1	1.3e-09	-0.86	0.02	0.98	FALSE
7	GTEx	Breast Mammary Tissue (Male)	ZXDC	0.04	0.01	lasso	8	0.01	1.4e-01	-5.9	6.3	3.5e-10	-0.92	0.03	0.52	FALSE
8	GTEx	Cells Transformed fibroblasts	ZXDC	0.19	0.06	lasso	7	0.09	4.0e-07	-4.8	6.0	2.7e-09	-0.86	0.05	0.95	FALSE
9	GTEx	Colon Sigmoid	ZXDC	0.34	0.17	enet	17	0.16	3.7e-06	-4.6	5.3	1.0e-07	-0.80	0.02	0.98	FALSE
10	GTEx	Colon Transverse	ZXDC	0.24	0.18	lasso	2	0.19	2.5e-09	-6.0	6.1	1.1e-09	-0.84	0.02	0.98	FALSE
11	GTEx	Esophagus Mucosa	ZXDC	0.20	0.17	lasso	6	0.19	1.0e-12	-6.0	6.3	3.0e-10	-0.85	0.02	0.98	FALSE
12	GTEx	Esophagus Muscularis	ZXDC	0.22	0.16	enet	25	0.17	1.6e-10	-6.0	5.2	1.6e-07	-0.81	0.02	0.98	FALSE
13	GTEx	Heart Atrial Appendage	ZXDC	0.18	0.04	lasso	5	0.01	7.2e-02	-6.1	6.0	1.5e-09	-0.83	0.02	0.93	FALSE
14	GTEx	Nerve Tibial	ZXDC	0.26	0.21	lasso	4	0.23	2.7e-16	-5.9	6.0	2.0e-09	-0.85	0.02	0.98	FALSE
15	GTEx	Pituitary	ZXDC	0.17	0.19	lasso	2	0.16	9.2e-05	-5.9	6.0	2.2e-09	-0.87	0.02	0.93	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	ZXDC	0.21	0.12	lasso	4	0.12	6.5e-07	-5.9	6.0	2.6e-09	-0.89	0.02	0.98	FALSE
17	GTEx	Skin Sun Exposed Lower leg	ZXDC	0.22	0.12	enet	28	0.13	6.8e-11	-5.9	5.7	1.5e-08	-0.81	0.02	0.98	FALSE
18	GTEx	Spleen	ZXDC	0.34	0.18	enet	5	0.15	9.9e-05	-6.3	5.4	5.3e-08	-0.94	0.01	0.98	FALSE
19	GTEx	Stomach	ZXDC	0.13	0.10	lasso	2	0.08	1.7e-04	-6.1	6.1	1.1e-09	-0.81	0.02	0.97	FALSE
20	GTEx	Thyroid	ZXDC	0.27	0.16	lasso	5	0.21	4.4e-16	-5.9	6.3	2.2e-10	-0.84	0.02	0.98	TRUE
21	METSIM	Adipose	ZXDC	0.13	0.15	lasso	11	0.16	5.2e-24	-6.0	6.0	1.7e-09	-0.86	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	UROC1	0.02	0.02	enet	5	0.02	4.9e-05	-5.6	-5.9	4.0e-09	0.70	0.06	0.92	FALSE
23	The Cancer Genome Atlas	Glioblastoma Multiforme	UROC1	0.30	0.14	lasso	7	0.12	1.4e-04	-4.7	-5.2	1.6e-07	0.74	0.05	0.83	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UROC1	0.12	0.12	lasso	4	0.14	3.0e-08	-6.1	-5.9	3.1e-09	0.78	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	UROC1	0.05	0.05	lasso	4	0.05	1.6e-06	-5.8	-5.8	6.5e-09	0.71	0.08	0.92	FALSE
26	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	UROC1	0.12	0.05	blup	88	0.05	3.6e-04	-4.7	-6.3	2.5e-10	0.79	0.03	0.94	FALSE
27	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UROC1	0.18	0.01	enet	15	0.09	9.0e-05	-4.7	-5.2	2.4e-07	0.57	0.03	0.56	FALSE
28	The Cancer Genome Atlas	Rectum Adenocarcinoma	CHST13	0.35	0.07	blup	66	0.07	1.1e-02	-4.2	6.0	1.5e-09	-0.41	0.04	0.07	FALSE