[Hub]/) : Traits : Heel T-Score :

chr3:123,753,964-125,314,016

Best TWAS P=1.71e-09 · Best GWAS P=5.04e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-71H17.9 0.15 0.13 lasso 4 0.13 4.8e-11 5.8 5.9 4.5e-09 0.96 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum RP11-71H17.9 0.25 0.20 enet 17 0.23 4.8e-12 5.8 6.0 1.8e-09 0.96 0.02 0.98 TRUE
3 GTEx Adrenal Gland RP11-71H17.9 0.29 0.21 lasso 6 0.20 7.2e-08 5.3 5.5 4.0e-08 0.91 0.02 0.98 FALSE
4 GTEx Artery Aorta RP11-71H17.9 0.36 0.22 enet 16 0.22 1.6e-12 5.3 5.8 8.1e-09 0.94 0.03 0.97 FALSE
5 GTEx Artery Tibial RP11-71H17.9 0.13 0.13 enet 12 0.13 3.7e-10 5.3 5.9 3.8e-09 0.94 0.03 0.97 FALSE
6 GTEx Brain Hypothalamus RP11-71H17.9 0.39 0.13 enet 38 0.10 2.2e-03 5.7 5.2 2.5e-07 0.84 0.02 0.95 FALSE
7 GTEx Brain Nucleus accumbens basal ganglia RP11-71H17.9 0.21 0.06 enet 15 0.07 5.0e-03 5.8 5.9 3.2e-09 0.97 0.03 0.88 FALSE
8 GTEx Cells EBV-transformed lymphocytes RP11-71H17.9 0.44 0.38 enet 15 0.37 6.0e-13 5.8 5.6 2.5e-08 0.98 0.01 0.99 FALSE
9 GTEx Cells Transformed fibroblasts ITGB5 0.16 0.14 lasso 7 0.11 1.8e-08 5.3 5.6 2.4e-08 0.83 0.09 0.91 FALSE
10 GTEx Cells Transformed fibroblasts RP11-71H17.9 0.24 0.29 enet 15 0.30 6.1e-23 5.8 5.6 1.9e-08 0.98 0.01 0.99 FALSE
11 GTEx Colon Sigmoid RP11-71H17.9 0.18 0.02 enet 10 0.05 6.7e-03 5.2 5.7 1.6e-08 0.97 0.02 0.98 FALSE
12 GTEx Colon Transverse RP11-71H17.9 0.18 0.24 lasso 5 0.22 5.0e-11 5.8 5.8 6.2e-09 1.00 0.01 0.99 FALSE
13 GTEx Esophagus Muscularis RP11-71H17.9 0.21 0.22 lasso 5 0.21 4.6e-13 5.8 5.6 1.9e-08 0.99 0.01 0.99 FALSE
14 GTEx Heart Left Ventricle RP11-71H17.9 0.18 0.21 lasso 9 0.19 2.6e-10 5.7 5.7 9.7e-09 0.99 0.01 0.99 FALSE
15 GTEx Lung RP11-71H17.9 0.16 0.16 lasso 4 0.16 6.9e-12 5.7 5.8 5.4e-09 0.99 0.01 0.99 FALSE
16 GTEx Muscle Skeletal RP11-71H17.9 0.12 0.07 lasso 4 0.06 8.6e-07 5.7 6.0 1.7e-09 0.90 0.01 0.99 FALSE
17 GTEx Pancreas RP11-71H17.9 0.19 0.22 lasso 3 0.18 6.4e-08 5.3 5.3 1.1e-07 0.97 0.03 0.97 FALSE
18 GTEx Small Intestine Terminal Ileum RP11-71H17.9 0.32 0.15 lasso 10 0.13 7.3e-04 5.7 5.5 2.9e-08 0.97 0.02 0.95 FALSE
19 GTEx Stomach RP11-71H17.9 0.21 0.24 lasso 3 0.20 4.4e-10 5.7 5.7 1.2e-08 0.99 0.01 0.99 FALSE
20 YFS Blood UMPS 0.02 0.01 bslmm 622 0.01 4.3e-04 5.3 5.3 1.0e-07 0.79 0.02 0.97 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ITGB5 0.03 0.02 blup 116 0.03 8.2e-05 2.9 5.2 2.3e-07 0.83 0.12 0.74 FALSE