[Hub]/) : Traits : Heel T-Score : ← →

chr3:127,639,072-129,284,415

Best TWAS P=4.86e-11 · Best GWAS P=2.03e-08 conditioned to 0.949

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RPN1 0.14 0.04 enet 19 0.06 1.9e-05 5.3 6.2 4.1e-10 0.72 0.03 0.96 FALSE
2 GTEx Brain Cerebellar Hemisphere RP11-723O4.2 0.29 0.02 lasso 4 0.07 6.2e-03 -3.9 -5.2 2.4e-07 -0.05 0.09 0.21 FALSE
3 GTEx Esophagus Muscularis RPN1 0.19 0.11 lasso 6 0.10 7.3e-07 5.1 5.3 9.5e-08 0.73 0.05 0.94 FALSE
4 GTEx Lung RPN1 0.08 0.06 lasso 4 0.04 2.6e-04 5.3 5.3 1.1e-07 0.69 0.04 0.92 FALSE
5 GTEx Testis RPN1 0.30 0.15 enet 22 0.15 2.8e-07 5.1 6.6 4.9e-11 0.79 0.06 0.94 TRUE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma H1FX 0.02 0.00 blup 36 0.00 5.1e-01 2.3 -5.5 5.1e-08 -0.09 0.01 0.28 TRUE
7 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RPN1 0.10 0.02 blup 59 0.02 3.6e-02 3.8 5.1 2.8e-07 0.73 0.02 0.78 FALSE