Best TWAS P=4.29e-08 · Best GWAS P=4e-12 conditioned to 1.14e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | SEH1L | 0.2 | 0.03 | lasso | 3 | 0.02 | 6.0e-02 | -5.4 | -5.5 | 5.1e-08 | -0.38 | 0.10 | 0.12 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | PTPN2 | 0.1 | 0.08 | lasso | 4 | 0.07 | 1.1e-09 | -5.4 | 5.5 | 4.3e-08 | 0.52 | 0.84 | 0.16 | TRUE |