[Hub]/) : Traits : Hypothyroidism (self reported) :

chr18:12,090,696-13,687,136

Best TWAS P=4.29e-08 · Best GWAS P=4e-12 conditioned to 1.14e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland SEH1L 0.2 0.03 lasso 3 0.02 6.0e-02 -5.4 -5.5 5.1e-08 -0.38 0.10 0.12 TRUE
2 ROSMAP Brain Pre-frontal Cortex PTPN2 0.1 0.08 lasso 4 0.07 1.1e-09 -5.4 5.5 4.3e-08 0.52 0.84 0.16 TRUE