TWAS
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Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
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chr18:66,371,289-68,204,223
Best TWAS P=1.38e-08 · Best GWAS P=3.19e-09 conditioned to 0.0723
66.5M
67M
67.5M
68M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
CD226
0.04
0.04
enet
7
0.05
5.3e-10
5.8
-5.7
1.4e-08
-0.91
0.00
1.00
TRUE
1
NTR
Blood
DOK6
0.18
0.18
lasso
5
0.18
3.2e-56
5.8
5.6
2.0e-08
0.96
0.01
0.99
FALSE