TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hypothyroidism (self reported)
:
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chr1:156,078,249-157,482,371
Best TWAS P=7.45e-08 · Best GWAS P=6.45e-08 conditioned to 0.339
156M
156.2M
156.4M
156.6M
156.8M
157M
157.2M
157.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
SH2D2A
0.13
0.05
lasso
5
0.03
0.0023
5.2
-5.4
7.4e-08
-0.95
0
0.99
TRUE