Best TWAS P=2.46e-11 · Best GWAS P=2.74e-14 conditioned to 0.000166
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Thyroid Carcinoma | MPST | 0.08 | 0.09 | lasso | 5 | 0.06 | 1.4e-06 | 5.5 | 6.0 | 2.6e-09 | 0.68 | 0.3 | 0.69 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | TST | 0.05 | 0.04 | lasso | 2 | 0.04 | 9.9e-05 | 5.5 | 6.7 | 2.5e-11 | 0.81 | 0.0 | 0.95 | TRUE |