Best TWAS P=3.61e-08 · Best GWAS P=3.31e-08 conditioned to 0.0215
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CPSF3L | 0.08 | 0.00 | lasso | 4 | 0.00 | 8.9e-01 | 5.1 | 5.2 | 1.8e-07 | 0.72 | 0.03 | 0.60 | FALSE |
| 2 | GTEx | Esophagus Mucosa | SDF4 | 0.05 | 0.00 | enet | 12 | 0.00 | 1.5e-01 | 3.4 | -5.2 | 1.7e-07 | -0.66 | 0.04 | 0.65 | FALSE |
| 3 | GTEx | Ovary | ANKRD65 | 0.67 | 0.15 | enet | 47 | 0.24 | 1.1e-06 | 4.4 | -5.2 | 2.6e-07 | -0.61 | 0.15 | 0.35 | FALSE |
| 4 | METSIM | Adipose | CPSF3L | 0.04 | 0.00 | bslmm | 254 | 0.02 | 2.2e-04 | 5.3 | 5.5 | 3.6e-08 | 0.65 | 0.02 | 0.91 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | SLC35E2 | 0.03 | 0.00 | blup | 291 | 0.01 | 1.4e-02 | 1.5 | -5.2 | 1.7e-07 | -0.24 | 0.04 | 0.48 | TRUE |