TWAS hub - SLC35E2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3510	0.0700	3.8e-12	0.146	0.115	0.174	0.134	0.159	2.1e-17	7.1e-14	1.0e-20	5.1e-16	5.9e-19
2	GTEx	Adipose Visceral Omentum	0.1320	0.0610	4.5e-03	0.132	NA	0.101	NA	0.122	2.5e-07	NA	6.6e-06	NA	6.9e-07
3	GTEx	Artery Aorta	0.3330	0.0900	5.9e-05	0.125	NA	0.180	NA	0.210	2.2e-07	NA	3.4e-10	NA	9.1e-12
4	GTEx	Cells Transformed fibroblasts	0.4750	0.0820	3.3e-04	0.282	NA	0.244	NA	0.263	2.6e-21	NA	2.9e-18	NA	7.9e-20
5	GTEx	Muscle Skeletal	0.1869	0.0711	6.3e-05	0.155	NA	0.149	NA	0.156	5.2e-15	NA	2.0e-14	NA	4.6e-15
6	GTEx	Nerve Tibial	0.2065	0.0829	4.1e-03	0.118	NA	0.112	NA	0.112	1.0e-08	NA	2.7e-08	NA	2.7e-08
7	ROSMAP	Brain Pre-frontal Cortex	0.0348	0.0172	1.1e-02	0.001	0.010	0.009	0.010	0.002	2.1e-01	1.4e-02	2.1e-02	1.5e-02	1.8e-01
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0264	0.0136	6.6e-04	0.028	0.006	0.005	NA	-0.002	3.3e-04	7.0e-02	8.6e-02	NA	6.6e-01
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0293	0.0188	4.7e-03	-0.002	0.007	-0.002	NA	0.000	7.5e-01	5.3e-02	8.0e-01	NA	3.5e-01
10	TCGA	Brain Lower Grade Glioma	0.0433	0.0191	2.6e-06	0.033	0.037	0.040	NA	0.052	1.0e-04	4.6e-05	2.3e-05	NA	1.4e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Comparative body size at age 10	6.9	19.0	30.1	5.2	3.3	4.2	3.9	4.0	3.6	3.8	-4.9	5.5	4.6
Breastfed as a baby	5.9	7.3	20.6	3.0	1.8	1.9	1.8	1.8	2.2	-1.0	-3.6	4.5	3.3
Systolic Blood Pressure	5.6	27.9	81.9	-5.6	1.3	0.4	2.0	1.9	0.5	-4.9	9.1	-9.0	-7.2
Impedance of whole body	4.8	24.4	50.1	-6.4	-3.0	-2.1	-2.2	-2.1	-4.0	-5.4	7.1	-7.0	-6.1
Impedance of arm (left)	4.0	18.3	38.4	-5.6	-2.0	-1.4	-1.5	-1.4	-3.5	-5.3	6.2	-5.8	-5.4
Irritable Bowel Disease (IBD)	3.9	9.4	27.4	-3.1	-0.6	0.0	-0.5	-0.7	-0.2	-5.2	4.8	-4.2	-3.9
Impedance of leg (right)	3.8	18.2	29.8	-5.4	-4.0	-3.0	-3.3	-3.2	-4.0	-3.3	5.3	-5.5	-4.7
Miserableness	3.7	6.4	10.2	-2.4	-2.2	-3.2	-2.7	-2.9	-2.6	-1.2	2.3	-2.9	-2.3
Medication: Co-codamol	3.6	4.2	9.0	2.1	1.3	2.3	1.8	1.9	3.0	1.4	-2.2	1.8	2.0
Qualifications: nursing, teaching	3.5	5.4	10.2	1.2	-3.1	-2.6	-3.2	-3.2	-2.9	1.4	-1.6	1.1	1.4
Impedance of arm (right)	3.4	15.8	33.4	-5.0	-2.2	-1.4	-1.7	-1.6	-3.3	-4.9	5.8	-5.4	-5.0
Systolic blood pressure, automated reading	3.3	9.5	25.3	-2.7	2.2	1.3	2.6	2.5	1.1	-2.7	5.0	-4.6	-3.8
Impedance of leg (left)	3.3	15.9	29.6	-5.0	-3.6	-2.4	-2.8	-2.6	-3.5	-3.3	5.3	-5.4	-4.4
Medication: Blood pressure	3.3	6.3	10.6	-2.4	2.8	0.7	3.2	2.9	1.3	-2.1	3.2	-2.4	-2.7
Ulcerative Colitis (UC)	3.1	5.9	24.5	-1.9	-1.1	0.0	-0.9	-1.1	-0.3	-5.0	3.5	-3.0	-2.5
Body mass index (BMI)	3.1	13.3	25.2	3.8	3.5	2.5	4.0	3.8	2.3	2.8	-4.0	5.0	3.9
Number of operations (self-reported)	3.1	4.7	7.7	2.5	2.3	2.8	2.6	2.8	2.3	0.7	-1.5	1.8	1.1
Bilateral oophorectomy (both ovaries removed)	3.0	3.5	6.1	2.0	2.0	2.5	2.0	2.1	2.3	0.2	-1.0	1.9	1.7
Vitamin and mineral supplements	2.9	4.0	8.5	-2.7	1.7	-0.1	1.6	1.2	1.1	-2.1	2.9	-2.4	-2.4
Tinnitus: Yes, now most or all of the time	2.9	3.4	9.6	-0.4	2.8	1.9	3.1	3.0	1.9	-0.3	0.2	0.0	-0.8
BMI	2.8	16.3	39.9	3.8	3.1	2.3	3.4	3.3	2.4	3.6	-5.1	6.3	5.1
Alcohol usually taken with meals	2.8	4.6	11.0	-2.0	-2.1	-2.5	-2.1	-2.2	-3.3	-1.6	1.4	-1.7	-2.0
Pulse wave reflection index	2.8	3.4	7.1	2.1	0.6	1.8	0.6	0.8	2.3	1.4	-2.1	2.7	2.6
Exposure to tobacco smoke outside home	2.8	3.7	10.8	2.5	-0.8	1.4	-0.2	0.1	1.3	1.5	-2.1	3.0	3.3
Supplements: Vitamin C	2.8	3.3	5.6	1.8	-2.4	-1.2	-2.4	-2.2	-0.4	0.5	-1.8	1.8	2.2
Supplements: Fish oil (including cod liver oil)	2.8	3.7	10.2	2.1	-1.1	1.3	-0.4	-0.1	0.2	2.0	-3.2	2.5	3.0
Supplements: Glucosamine	2.7	3.5	7.8	2.0	-2.4	-0.3	-1.5	-1.3	-1.0	1.1	-2.8	2.0	2.7
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.2	7.2	-0.3	2.3	2.4	2.6	2.7	2.0	1.1	-0.5	0.7	0.8
Hearing difficulty/problems: Yes	2.5	3.8	8.2	-0.1	2.2	2.1	2.9	2.8	2.7	-0.9	-0.8	1.9	0.8
Alzheimer’s Disease (in father)	2.4	2.6	6.5	1.0	1.7	2.5	2.0	2.2	2.2	0.4	-0.5	1.1	0.3
Length of working week for main job	2.4	2.6	6.4	-2.2	0.8	-0.1	1.1	0.9	-0.7	-1.0	2.3	-2.5	-2.4
Pulse wave peak to peak time	2.4	2.8	4.4	-1.7	-1.4	-1.9	-1.4	-1.5	-2.0	-1.4	1.4	-2.1	-1.7
Ever had bowel cancer screening	2.4	2.8	8.5	1.1	0.3	1.5	0.2	0.4	1.6	0.5	-2.3	2.7	2.9
Whole body water mass	2.4	13.4	34.2	5.8	2.5	0.5	1.2	0.9	3.4	2.6	-5.0	5.3	4.5
Crohns Disease (2017)	2.3	5.0	14.2	-2.2	-0.6	0.0	-0.6	0.0	-0.4	-3.5	3.8	-3.0	-3.0
Arm fat mass (right)	2.3	9.3	18.6	3.5	3.1	2.0	3.4	3.2	1.7	1.9	-3.2	4.3	3.1
Whole body fat-free mass	2.3	12.9	34.0	5.8	2.5	0.5	1.2	1.0	3.4	2.5	-4.8	5.1	4.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	6.6	-2.4	-0.8	-0.6	-0.5	-0.5	-0.6	-2.2	2.3	-2.6	-1.6
Arm fat-free mass (left)	2.3	11.8	29.4	5.4	2.3	0.2	1.1	0.9	3.1	2.6	-4.7	5.0	4.2
Arm predicted mass (left)	2.3	11.9	31.9	5.7	2.1	0.2	1.0	0.8	3.0	2.5	-4.7	5.0	4.3
Ever used hormone-replacement therapy (HRT)	2.2	2.8	5.8	0.8	-2.0	0.2	-1.6	-1.3	-1.7	1.3	-2.3	1.7	2.4
Hayfever, allergic rhinitis or eczema	2.2	4.7	13.1	-3.0	0.3	0.0	0.9	0.8	-0.2	-2.7	3.6	-2.8	-3.0
Trunk fat-free mass	2.2	12.4	35.6	6.0	1.8	-0.2	0.4	0.1	3.0	2.5	-4.9	5.1	4.4
Trunk predicted mass	2.2	12.6	36.1	6.0	1.9	-0.1	0.5	0.2	3.1	2.5	-4.9	5.1	4.4
Leg fat-free mass (right)	2.2	11.8	27.6	5.2	3.1	1.2	2.1	1.9	3.4	1.9	-4.3	4.7	3.9
Osteoarthritis (self-reported)	2.2	2.9	7.1	2.1	0.5	1.7	0.7	0.9	1.3	1.3	-2.7	2.0	2.4
Leg predicted mass (right)	2.2	12.0	28.0	5.3	3.1	1.2	2.1	1.9	3.5	1.9	-4.3	4.7	4.0
Basal metabolic rate	2.2	12.0	30.5	5.5	2.5	0.5	1.5	1.2	3.1	2.2	-4.6	5.1	4.2
Average weekly beer plus cider intake	2.2	3.2	5.7	1.3	2.2	2.2	2.2	2.3	2.4	1.3	-0.9	1.0	0.9
Vascular/heart problems diagnosed by doctor	2.2	5.9	17.6	1.8	-1.6	-0.8	-2.3	-2.1	-1.4	1.5	-4.2	3.8	2.5
Fed-up feelings	2.1	3.8	11.0	-3.3	0.5	-0.8	-0.1	-0.2	-0.9	-2.1	2.6	-2.8	-2.4
Noisy workplace	2.1	2.5	5.9	0.4	0.9	2.3	1.9	2.0	2.4	0.0	-1.1	1.6	1.5
Arm fat-free mass (right)	2.1	10.9	25.7	5.1	2.2	0.2	1.0	0.8	3.0	2.6	-4.5	4.8	4.2
Medication for hormone replacement therapy	2.0	2.2	5.4	1.4	-2.3	0.3	-1.9	-1.6	0.2	0.9	-0.8	1.4	2.3
Leg fat-free mass (left)	2.0	10.6	23.7	4.9	3.0	1.0	2.0	1.8	3.2	1.9	-4.1	4.6	3.7
Multivitamins +/- minerals	2.0	2.6	7.2	2.4	-0.3	0.9	-0.2	0.1	-0.4	1.6	-2.7	2.4	1.9
Leg predicted mass (left)	2.0	10.4	23.1	4.8	3.0	1.0	2.0	1.7	3.2	1.9	-4.0	4.5	3.7
Waist circumference	2.0	7.4	20.2	3.4	2.0	0.9	2.4	2.2	1.4	1.6	-3.3	4.5	3.4
Chronic bronchitis/emphysema (mother)	2.0	2.3	6.3	2.5	1.0	0.2	1.1	1.0	0.7	2.3	-1.8	1.7	1.3
Arm predicted mass (right)	2.0	10.1	24.4	4.9	1.9	-0.0	0.9	0.6	2.8	2.5	-4.3	4.7	4.0
Cardiovascular Disease	1.9	6.4	21.1	-2.9	1.0	0.1	1.6	1.4	0.7	-1.6	4.6	-4.2	-3.0
Pulse wave Arterial Stiffness index	1.9	2.2	3.9	1.8	1.1	1.5	1.0	1.1	1.9	1.2	-1.2	2.0	1.6
Tense / ‘highly strung’	1.9	3.2	6.8	-2.6	-1.1	-2.5	-1.2	-1.5	-1.7	-0.3	1.2	-2.3	-2.0
Chest pain or discomfort	1.9	2.8	7.5	-2.5	0.3	-0.6	-0.2	-0.3	0.1	-1.8	2.7	-2.7	-1.6
Had major operations	1.9	2.2	5.3	2.3	1.2	0.4	1.5	1.3	0.9	2.3	-1.8	1.5	0.4
Arm fat mass (left)	1.9	7.9	16.3	3.1	2.9	1.7	3.2	3.0	1.4	1.6	-2.9	4.0	2.9
Lung FVC	1.8	8.9	20.5	-2.4	-2.9	-2.9	-2.8	-3.0	-2.2	-4.5	2.6	-2.8	-3.1
High blood pressure	1.8	4.9	15.1	-1.5	1.4	0.9	2.2	2.0	1.2	-1.4	3.9	-3.4	-2.2
Hearing difficulty/problems with background noise	1.8	2.8	5.9	-0.4	1.9	2.0	2.4	2.4	1.9	-0.5	-1.3	1.5	0.9
Fluid intelligence score	1.8	3.8	8.1	0.6	-2.8	-2.3	-2.9	-2.8	-2.7	0.5	-0.7	0.0	-0.1
Weight	1.8	9.0	21.0	4.1	2.8	1.0	2.4	2.2	2.3	1.7	-3.5	4.6	3.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	3.1	-0.9	1.4	1.8	1.5	1.6	1.8	-1.5	1.5	-1.4	-1.1
Heart attack	1.7	2.2	5.9	-1.9	-0.8	-0.7	-0.3	-0.4	-0.9	-2.4	2.3	-1.8	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	3.4	-1.7	-0.5	-1.8	-1.0	-1.2	-0.6	-1.6	1.8	-1.4	-1.4
Medication: Atorvastatin	1.7	2.1	3.9	-0.9	-1.3	-2.0	-1.4	-1.6	-1.1	-0.9	1.8	-1.6	-1.4
Prostate Cancer	1.6	2.2	4.4	-2.0	-0.4	-1.2	-0.5	-0.7	-0.8	-1.8	2.0	-2.1	-1.8
Forced vital capacity (FVC)	1.6	6.1	20.3	-1.6	-1.6	-2.3	-2.2	-2.5	-0.5	-4.5	2.3	-2.9	-2.5
Arm fat percentage (right)	1.6	6.1	13.1	2.2	2.7	2.1	3.6	3.5	0.7	1.3	-1.9	3.1	2.0
Hip circumference	1.6	6.9	18.3	3.3	2.4	1.0	2.3	2.1	1.4	1.2	-3.4	4.3	2.9
Number of full brothers	1.6	2.0	6.2	0.9	-0.6	-0.3	-0.9	-0.8	0.5	1.3	-2.5	2.2	2.0
Medication: Blood pressure	1.6	2.9	5.6	-0.8	-2.4	-1.7	-1.9	-1.9	-1.8	0.7	1.7	-2.3	-0.7
Medication: Ibuprofen	1.6	1.9	4.4	0.9	-1.2	-0.5	-1.5	-1.4	-0.9	1.1	-1.6	2.1	1.9
Hypertension (Self-reported)	1.6	4.3	12.8	-1.5	1.4	1.0	2.1	2.0	1.2	-1.1	3.6	-3.1	-2.0
Long-standing illness, disability or infirmity	1.6	2.4	6.1	-0.5	2.2	1.4	2.5	2.4	2.1	0.5	0.2	0.3	-0.2
Heart attack/myocardial infarction (self-reported)	1.6	2.1	5.5	-1.6	-0.8	-0.7	-0.3	-0.3	-0.7	-2.3	2.4	-1.9	-1.5
Leg fat mass (left)	1.6	6.4	13.9	2.7	2.5	1.3	2.9	2.7	1.6	1.6	-2.6	3.7	2.8
Age when periods started (menarche)	1.5	3.7	8.4	-1.6	-2.0	-2.6	-2.8	-2.9	-1.7	-1.8	0.7	-0.7	-0.5
Mouth/teeth dental problems	1.5	2.3	4.7	-1.4	-1.3	-2.0	-1.9	-2.0	-2.2	-0.0	-0.0	-1.2	-1.3
Forced expiratory volume in 1-second (FEV1)	1.5	5.1	19.4	-1.8	-0.4	-1.3	-0.8	-1.1	-0.3	-4.4	2.5	-3.1	-3.0
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	4.5	0.4	1.5	2.1	2.0	2.0	1.8	-0.7	0.7	0.2	0.1
Arm fat percentage (left)	1.5	5.8	13.7	1.7	2.8	2.1	3.7	3.6	0.6	1.1	-1.7	2.9	1.9
Mineral and other dietary supplements	1.5	2.0	5.0	-1.1	1.9	-0.5	1.1	0.9	0.4	-0.6	2.1	-1.7	-2.2
Allergy or Eczema	1.4	3.8	11.7	-2.5	-0.1	0.1	0.3	0.3	-0.2	-2.6	3.4	-2.3	-2.8
High blood pressure (mother)	1.4	2.0	7.4	-0.8	-0.5	0.1	0.0	0.1	-0.4	-1.9	2.7	-2.6	-1.0
Allergy	1.4	3.2	8.2	2.4	-0.5	0.0	-0.9	-0.8	-0.1	2.2	-2.9	2.2	2.6
Medication: Lansoprazole	1.4	1.6	4.5	1.1	-0.1	0.6	-0.2	-0.1	-0.1	2.0	-1.8	1.5	2.1
Hair/balding pattern: Pattern 4	1.4	3.3	8.8	1.2	-3.0	-1.8	-2.5	-2.5	-1.0	1.4	-1.4	0.2	1.5
Forced vital capacity (FVC), Best measure	1.4	5.2	13.2	-1.3	-2.1	-2.6	-2.8	-3.0	-1.0	-3.6	1.2	-1.9	-1.6
Leg fat mass (right)	1.4	5.6	13.6	2.5	2.2	1.1	2.6	2.4	1.4	1.5	-2.5	3.7	2.6
Knee pain experienced in last month	1.4	2.2	3.9	0.5	1.4	1.5	1.5	1.6	0.6	2.0	-1.9	1.5	1.6
Breast cancer (self-reported)	1.4	1.7	5.6	-0.1	1.2	1.2	1.1	1.2	0.6	-0.1	1.4	-2.4	-1.8
Eye problems/disorders: Glaucoma	1.4	1.6	2.9	-1.1	1.5	1.2	1.7	1.7	0.4	-0.3	1.3	-1.4	-1.1
Medication: Atenolol	1.3	1.6	3.8	-2.0	0.9	0.3	1.2	1.1	0.9	-1.0	1.4	-1.7	-1.4
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	3.1	-1.0	1.7	1.8	1.6	1.7	1.6	-0.2	0.3	-0.5	-0.3
Time employed in main current job	1.3	1.5	4.6	2.1	1.7	0.7	1.2	1.1	1.6	0.9	-0.2	0.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	2.6	0.7	-1.0	-0.8	-1.4	-1.3	-1.3	1.4	-1.5	1.6	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	14.4	-1.8	-1.1	-1.9	-1.6	-1.8	-0.6	-3.8	1.6	-2.3	-2.2
Birth weight of first child	1.3	2.4	8.0	2.3	-0.1	0.4	0.1	0.2	-0.2	2.0	-2.8	2.0	1.7
Family relationship satisfaction	1.3	1.7	5.0	1.2	-0.3	0.8	-0.2	-0.1	1.2	0.3	-1.8	2.1	2.2
Medication for cholesterol	1.3	1.9	6.9	1.8	-0.6	-0.1	-1.1	-1.0	-0.7	1.3	-2.6	1.6	1.4
Leg fat percentage (left)	1.3	4.8	9.1	1.7	2.1	1.7	3.0	2.9	1.0	1.3	-1.8	3.0	2.3
Average weekly spirits intake	1.2	1.5	3.5	1.9	-0.9	-0.4	-0.7	-0.7	0.2	1.4	-1.5	1.6	1.7
Illnesses of siblings	1.2	1.7	4.5	-0.6	-1.9	-1.1	-2.1	-2.0	-1.1	-1.3	-0.0	-0.1	-0.1
Blood clot in the leg (DVT)	1.2	1.5	5.5	2.4	-0.1	-0.2	-0.4	-0.4	0.2	1.4	-1.9	1.6	1.1
High blood pressure (siblings)	1.2	1.7	5.3	0.4	1.9	1.2	2.3	2.3	-0.1	1.3	-0.2	-0.1	-0.2
Qualifications: College or University degree	1.2	3.9	11.3	2.8	-0.8	0.5	-0.3	-0.1	-1.9	2.5	-3.4	2.7	1.4
Heart disease (mother)	1.2	1.5	5.4	-0.8	-1.0	-1.3	-0.7	-0.7	-1.0	0.2	1.6	-2.3	-1.3
Suffer from ‘nerves’	1.2	1.8	3.6	-1.1	-1.4	-1.9	-1.7	-1.9	-1.0	-0.0	0.8	-1.7	-0.6
Illnesses of father: High blood pressure	1.2	1.5	4.9	-1.5	0.7	-0.5	0.7	0.5	-0.3	0.2	1.7	-2.2	-1.7
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	3.0	-1.5	-1.5	-1.2	-1.7	-1.7	-0.7	-0.5	0.6	-1.1	-0.6
Lung FEV1/FVC ratio	1.1	5.6	16.6	-0.3	3.5	2.4	4.1	4.0	1.2	-0.1	1.0	-0.4	-1.6
Chronotype (morning person)	1.1	2.6	5.5	0.9	-2.1	-2.3	-2.1	-2.1	-2.3	0.7	-0.6	0.2	-0.4
Ever had hysterectomy (womb removed)	1.1	1.2	2.0	1.4	1.0	1.3	1.3	1.4	0.6	1.2	-0.7	1.0	0.5
Medication: Metformin	1.1	1.5	4.1	-0.3	2.0	1.4	1.8	1.8	1.5	-0.1	0.5	0.2	0.3
Nervous feelings	1.1	2.0	4.1	-2.0	-0.8	-1.5	-1.3	-1.4	-0.3	-1.7	1.5	-1.7	-1.1
Had other major operations	1.1	1.3	3.4	1.2	1.3	1.8	1.4	1.5	0.9	0.3	-0.7	0.5	0.8
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.0	-0.9	-0.7	-1.1	-0.6	-0.7	-0.7	-1.7	1.7	-1.6	-1.4
Alcohol intake versus 10 years previously	1.1	1.7	3.0	-1.2	1.1	0.8	1.2	1.2	1.7	-1.0	1.5	-1.7	-1.2
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	4.5	0.9	1.4	1.2	0.9	1.0	1.7	-0.9	-1.5	2.1	1.2
Glaucoma (self-reported)	1.1	1.3	2.2	-1.1	1.1	1.0	1.5	1.4	0.4	-0.4	1.3	-1.2	-1.3
Migraine (self-reported)	1.1	1.4	3.7	1.3	-1.2	0.9	-1.0	-0.7	0.8	1.3	-0.9	1.2	1.9
Whole body fat mass	1.1	4.7	8.8	2.0	2.6	1.3	3.0	2.8	1.2	0.8	-1.7	2.9	2.0
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	3.2	1.8	0.1	-0.4	-0.1	-0.2	-0.9	1.7	-1.7	1.5	0.9
Medication: Aspirin	1.1	1.4	4.4	-1.4	-0.4	-0.5	0.1	0.0	-1.0	-1.2	2.1	-1.4	-1.7
Ever taken oral contraceptive pill	1.1	1.2	2.9	-0.8	-1.2	-1.2	-1.0	-1.1	-1.4	-1.7	0.7	-1.1	-0.5
Mother’s age at death	1.1	1.4	4.5	2.1	-1.3	-0.3	-1.5	-1.3	-0.8	1.3	-0.5	0.4	1.0
Fractured/broken bones in last 5 years	1.1	1.4	6.0	-0.9	-1.5	-1.0	-1.1	-1.1	-2.5	-0.5	0.6	-0.6	-0.3
Cholesterol lowering medication	1.1	1.6	3.8	-1.9	1.0	-0.4	1.4	1.1	-0.7	-1.1	1.7	-1.1	-1.4
Depressed Affect (Nagel 2018)	1.0	2.2	8.6	-2.9	-0.0	-0.8	-0.5	-0.6	-1.2	0.3	1.4	-2.2	-1.9
Worry (Nagel 2018)	1.0	2.1	4.3	-1.9	-1.3	-2.1	-1.6	-1.8	-1.7	-0.5	0.2	-0.9	-1.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.6	0.4	0.0	1.4	0.5	0.6	0.8	1.4	-1.4	1.5	1.6
Chronic bronchitis/emphysema (father)	1.0	1.2	2.6	-0.5	-1.5	-1.6	-1.5	-1.6	-1.1	0.6	-0.5	-0.2	0.4
Worrier / anxious feelings	1.0	2.0	4.2	-1.2	-1.6	-1.8	-2.0	-2.1	-1.8	-0.4	-0.3	-0.7	-0.5
Number of full sisters	1.0	1.2	2.9	1.3	0.6	1.5	0.8	0.9	1.4	0.5	-0.6	0.8	1.7
Average weekly red wine intake	1.0	1.5	3.9	0.2	-2.0	-1.6	-1.5	-1.5	-1.9	-0.8	0.2	-0.2	-0.0
Eye problems/disorders: Cataract	1.0	1.1	4.2	0.9	-0.2	0.4	-0.3	-0.2	0.3	0.7	-2.1	1.9	1.3
Medication: Aspirin	1.0	1.4	3.7	-1.5	-0.7	-0.8	-0.1	-0.2	-1.2	-1.1	1.9	-1.3	-1.6
Myopia	1.0	1.5	3.8	1.7	0.3	0.7	0.4	0.4	1.3	-0.8	-1.5	1.9	1.6
Lupus	0.9	1.3	7.5	0.4	-2.7	0.0	0.0	0.0	-1.8	1.1	0.9	0.1	0.9
Serious illness, injury or assault to yourself	0.9	1.1	4.8	-0.8	0.1	2.2	0.5	0.9	1.5	-1.4	0.3	-0.0	0.5
Depression (self-reported)	0.9	1.1	3.1	-0.4	-1.7	-0.6	-1.6	-1.4	-1.3	0.9	-0.4	-0.4	0.1
Leg fat percentage (right)	0.9	3.4	8.2	1.5	1.5	1.2	2.4	2.4	0.6	1.3	-1.6	2.9	2.1
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.2	-0.0	1.4	0.4	1.5	1.3	0.8	-0.8	1.2	-0.7	-1.1
Medication: Omeprazole	0.9	1.0	2.4	-1.2	-1.5	-0.9	-1.5	-1.4	-0.3	-0.3	0.4	-0.9	-0.6
Overall health rating	0.9	1.9	4.0	-0.9	1.6	1.5	2.0	2.0	1.3	1.5	-0.8	0.7	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	5.3	1.1	-1.6	-1.8	-2.2	-2.3	-0.3	-0.2	-0.9	0.5	1.0
Commuting to job workplace: Walk	0.9	0.9	2.5	-1.6	-0.8	-1.1	-0.7	-0.9	-0.7	-1.2	0.8	-0.6	-0.9
Wears glasses or contact lenses	0.9	1.1	2.8	1.3	0.2	0.4	0.5	0.4	1.0	0.7	-1.6	1.7	1.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	4.3	2.1	0.3	0.3	0.0	0.0	0.5	1.2	-1.5	1.4	0.9
Maternal smoking around birth	0.8	1.2	3.7	-0.6	1.2	1.4	1.9	1.9	0.8	0.6	0.3	-0.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.6	-1.9	0.2	-0.8	-0.2	-0.3	-0.5	-0.8	1.5	-1.4	-0.9
Loud music exposure frequency	0.8	0.9	3.1	-1.1	0.5	0.2	0.7	0.6	0.5	-1.8	1.6	-0.4	-0.8
Headache pain in last month	0.8	1.4	3.5	0.4	1.5	1.4	1.5	1.5	1.9	0.6	-0.2	1.0	0.9
Medication for pain relief, constipation, heartburn	0.8	1.3	2.8	0.5	1.7	1.4	1.4	1.4	1.5	0.6	-1.2	0.6	0.3
Neck or shoulder pain in last month	0.8	1.1	3.2	1.2	-0.8	0.7	-0.4	-0.2	0.8	0.7	-1.8	1.6	1.4
Pulse rate, automated reading	0.8	2.7	6.2	1.9	1.6	2.5	2.0	2.2	0.7	1.5	-1.2	1.2	0.8
Number of self-reported non-cancer illnesses	0.8	1.4	2.7	-1.2	1.2	1.4	1.6	1.6	1.0	0.7	0.9	-0.9	-1.0
High cholesterol (Self-reported)	0.8	1.5	4.5	-0.5	1.2	2.0	2.0	2.1	0.1	0.2	0.7	-0.4	-0.4
Medication: Bendroflumethiazide	0.8	1.1	3.9	-0.9	0.8	0.2	1.0	0.8	0.0	-0.3	2.0	-1.7	-1.2
Basal cell carcinoma (self-reported)	0.8	0.9	2.4	1.3	-0.7	0.7	-0.8	-0.5	1.2	0.3	-1.0	0.9	1.6
Depression (Nagel 2018)	0.7	1.1	3.5	-1.9	-0.3	-0.9	-0.4	-0.5	-0.4	-1.1	1.5	-1.3	-0.7
Intelligence (Savage-Jansen 2018)	0.7	2.1	4.6	-0.8	-1.5	-1.6	-1.4	-1.5	-2.1	-1.4	1.0	-1.2	-1.5
Alzheimer’s Disease (including proxy)	0.7	1.0	2.9	0.2	1.5	1.4	1.7	1.7	0.6	0.2	-0.2	0.3	-0.3
Mean Putamen Volume	0.7	0.8	4.8	-1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-2.2
Blood Red Count	0.7	7.1	17.7	4.2	2.0	2.5	1.5	1.6	3.2	1.7	-2.5	3.1	3.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.5	-1.2	1.2	0.3	1.0	0.8	1.6	-0.8	0.5	-0.5	-0.7
Current tobacco smoking	0.7	1.2	4.1	0.8	-0.7	0.3	-0.4	-0.3	0.7	1.2	-1.6	1.3	2.0
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	4.8	0.0	-2.2	-1.5	-1.9	-1.9	-0.4	-0.3	-0.7	-0.0	0.4
Trunk fat mass	0.7	2.8	6.0	1.5	2.1	0.8	2.4	2.2	0.7	0.1	-1.2	2.4	1.6
Had menopause	0.7	0.8	2.3	0.9	0.2	1.0	0.2	0.4	-0.2	0.4	-1.5	1.3	1.5
Pain all over the body in last month	0.7	0.7	2.6	1.6	-0.5	0.5	-0.4	-0.3	0.7	0.5	-1.2	0.6	1.2
Hair/balding pattern: Pattern 3	0.7	1.1	2.3	-1.3	0.7	0.3	0.4	0.3	0.2	-1.5	1.5	-1.3	-1.4
Happiness	0.7	0.9	1.7	1.0	-1.3	-0.8	-1.1	-1.1	-0.7	0.0	-0.8	1.1	1.0
Illnesses of mother	0.7	0.9	3.0	-0.5	-0.2	-0.4	-1.2	-1.1	0.1	-0.7	-1.4	1.7	0.5
Exposure to tobacco smoke at home	0.7	0.8	2.4	-0.8	0.2	-0.5	0.4	0.3	-0.3	-1.4	1.6	-1.2	-0.9
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	3.0	0.4	-1.6	-0.8	-1.4	-1.3	-1.7	0.0	0.4	-1.1	-0.7
Medication: Amlodipine	0.7	1.0	2.0	-0.6	0.8	1.0	1.0	1.1	0.1	-0.3	1.2	-1.4	-1.2
Body fat percentage	0.7	2.7	8.2	0.5	2.0	1.4	2.9	2.7	0.2	0.1	-0.6	1.9	1.2
Medication: Seretide 50 evohaler	0.7	0.8	1.4	-0.5	1.2	0.8	1.2	1.2	0.4	-1.2	0.8	-0.9	-0.5
Mood swings	0.7	1.3	2.4	-0.4	-1.0	-1.1	-1.3	-1.4	-1.4	1.6	0.4	-1.5	-0.8
Friendships satisfaction	0.7	0.8	2.1	0.9	-0.9	0.4	-0.9	-0.6	-0.4	-0.5	-1.1	1.4	1.3
Back pain experienced in last month	0.7	1.0	4.6	-2.1	-0.2	0.1	0.1	0.1	-0.3	-1.6	0.7	-0.9	-0.9
Medication: Lisinopril	0.7	0.9	2.6	1.2	-0.0	0.8	0.2	0.3	0.7	0.6	-1.2	1.4	1.6
Alcohol drinker status: Previous	0.7	0.8	1.9	-0.9	-1.2	-0.1	-0.4	-0.3	-0.6	-0.5	1.2	-1.4	-1.0
Pack years of smoking	0.7	1.0	3.4	1.0	0.1	1.1	0.6	0.7	1.0	0.8	-0.5	1.3	1.8
Neuroticism (Nagel 2018)	0.6	1.4	6.7	-2.6	-0.3	-0.9	-0.7	-0.8	-0.7	-0.2	0.7	-1.6	-1.4
Neuroticism (2016)	0.6	0.8	2.0	-0.1	-0.9	-1.4	-1.2	-1.3	-1.0	-0.0	0.2	-0.8	-0.6
Diabetes (father)	0.6	0.7	1.8	0.6	-1.0	-0.2	-0.8	-0.7	-1.4	0.6	0.6	-1.3	-0.5
Diabetes (mother)	0.6	0.8	1.7	-1.2	0.6	-0.5	0.9	0.6	-0.1	0.0	1.1	-1.3	-1.1
Relative age voice broke	0.6	1.0	2.4	-0.9	1.5	0.5	1.5	1.4	0.7	-1.2	-0.1	0.2	-0.2
Sitting height	0.6	4.2	7.6	-0.8	-0.5	-2.8	-2.0	-2.4	-0.1	-2.3	2.2	-2.7	-2.5
Hair/balding pattern: Pattern 2	0.6	0.7	1.6	0.6	1.1	0.8	0.7	0.8	0.8	1.3	-0.9	0.8	0.4
Financial difficulties in last 2 years	0.6	0.9	2.8	-0.5	0.8	1.2	0.9	1.0	1.7	-0.8	1.1	-0.3	0.2
Peak expiratory flow (PEF)	0.6	1.4	6.6	-0.8	1.2	0.8	1.4	1.3	0.9	-2.6	-0.1	0.4	-0.4
Ever highly irritable/argumentative for 2 days	0.6	0.8	2.4	1.5	0.5	0.9	0.6	0.7	1.3	0.4	-0.8	0.6	0.8
Shortness of breath walking on level ground	0.6	0.7	3.6	0.8	-0.0	-0.5	0.2	0.0	1.1	-1.9	1.2	-0.4	-0.4
Illnesses of siblings: Diabetes	0.6	0.7	1.8	-0.1	0.7	1.0	0.8	0.8	1.2	-1.4	0.8	-0.8	-0.5
Smoking status: Current	0.6	1.0	3.2	0.8	-0.2	0.3	-0.1	-0.0	0.9	1.0	-1.4	1.3	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.4	7.4	-1.1	-0.9	-0.4	-0.6	-0.7	-0.3	-2.7	0.8	-1.1	-1.1
Alcohol drinker status: Never	0.6	0.7	1.3	0.9	-1.0	-1.1	-1.0	-1.0	-0.2	0.4	-1.0	0.6	0.4
Irritability	0.6	1.0	3.9	-2.0	-0.2	-0.7	-0.6	-0.7	0.2	-1.0	0.9	-1.5	-0.5
Commuting to job workplace: Cycle	0.6	0.7	2.8	1.7	0.2	0.6	0.2	0.2	0.5	0.7	-1.2	0.9	1.0
Verbal and Numeric Reasoning (VNR)	0.5	1.1	4.3	0.6	-1.2	-1.1	-1.2	-1.2	-2.1	-0.2	-0.1	-0.7	-0.9
Primary Biliary Cirrhosis	0.5	0.7	3.5	-1.4	0.0	0.0	0.0	0.0	0.0	-1.4	0.0	0.0	-1.9
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.0	-0.1	-1.1	-0.9	-1.4	-1.4	-0.8	0.1	0.1	0.1	0.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.4	-1.2	0.5	0.5	0.7	0.7	0.7	0.2	0.7	-1.0	-0.6
Severe depression (siblings)	0.5	0.6	2.3	0.8	-0.4	0.7	-0.4	-0.2	0.3	0.6	-0.6	1.0	1.5
Trunk fat percentage	0.5	2.0	6.6	0.2	1.9	1.0	2.6	2.4	-0.1	-0.6	-0.0	1.4	0.6
Hand grip strength (right)	0.5	1.3	3.3	0.7	1.8	-0.4	1.3	0.9	0.4	1.3	-1.6	1.3	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	4.2	-0.2	-2.0	-0.9	-1.6	-1.6	0.1	-1.0	-0.4	0.2	0.5
Medication: Simvastatin	0.5	0.8	2.4	-0.7	0.1	-0.5	0.5	0.4	-1.6	1.1	0.7	-1.1	-1.2
Neuroticism score	0.5	1.0	2.7	-1.2	-1.0	-1.2	-1.6	-1.6	-0.8	-0.3	-0.1	-0.9	0.1
Mouth/teeth dental problems: Dentures	0.5	0.9	1.6	0.2	0.9	1.0	1.2	1.2	1.3	0.5	-0.0	0.9	0.9
Medication: Cholesterol lowering	0.5	0.8	1.7	-0.4	-0.9	-0.7	-0.5	-0.5	-1.2	0.6	1.0	-1.3	-1.0
Lung cancer (father)	0.5	0.6	2.4	0.5	0.0	0.7	0.0	0.2	-0.1	0.9	-1.2	1.0	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.7	0.6	-0.3	0.8	-0.5	-0.3	0.4	0.6	-1.3	1.3	1.6
Number of children fathered	0.5	0.6	1.8	0.5	-1.3	-0.5	-0.8	-0.8	-0.8	-0.9	0.2	0.5	0.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.1	-0.1	1.1	0.3	1.4	1.3	0.6	-0.1	0.6	-0.4	-0.4
Emphysema/chronic bronchitis	0.5	0.6	1.6	-1.3	-0.9	-0.8	-0.5	-0.6	-0.7	-0.6	0.4	-0.7	-0.8
Medication: Allopurinol	0.5	0.7	1.7	0.2	-0.2	-1.3	-1.0	-1.1	0.6	-0.5	1.0	-0.8	-0.7
Leg pain on walking	0.5	0.6	2.7	0.4	-0.6	-1.6	-0.6	-0.8	-0.4	1.2	0.0	0.0	0.1
Osteoporosis (self-reported)	0.5	0.7	1.7	-1.1	0.2	0.4	0.5	0.6	0.6	-0.7	1.3	-1.3	-0.7
Medication: Gliclazide	0.5	0.6	1.5	-0.8	0.8	0.5	0.9	0.8	0.0	-0.6	0.7	-1.2	-0.8
Medication: Paracetamol	0.5	0.7	1.8	1.4	-1.3	-0.3	-1.1	-1.0	-0.3	-0.7	0.0	0.7	0.8
Ever depressed for a whole week	0.5	0.6	1.3	-0.6	1.0	1.2	0.9	0.9	1.1	0.0	0.1	-0.8	0.1
Pain experienced in last month	0.5	0.9	2.5	0.1	-1.0	-1.2	-1.1	-1.1	-1.6	-0.5	0.9	-0.6	-0.5
Blood Platelet Count	0.4	5.1	33.5	-0.2	-1.7	-1.9	-0.4	-0.4	-5.8	-0.9	2.3	-1.8	-1.3
Sensitivity / hurt feelings	0.4	0.7	2.6	0.7	-0.4	0.7	-0.6	-0.5	1.1	0.6	-0.7	0.4	1.6
Supplements: Zinc	0.4	0.5	1.7	0.2	-0.5	0.1	-0.5	-0.4	1.3	-1.1	-0.4	0.6	0.8
Pack years adult smoking proportion	0.4	0.6	2.3	0.7	-0.0	0.7	0.4	0.5	0.7	1.0	-0.3	1.0	1.5
Average weekly fortified wine intake	0.4	0.5	1.8	-0.9	0.1	-0.2	0.1	0.0	0.6	-1.1	-0.8	1.3	0.3
Medication: Levothyroxine sodium	0.4	0.7	1.9	-0.3	0.7	1.0	0.4	0.5	0.9	0.6	1.4	-1.2	-0.3
Father’s age at death	0.4	0.5	1.6	0.9	0.1	-0.2	-0.3	-0.4	0.3	1.2	-1.2	0.4	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.6	-1.1	0.3	-0.4	0.4	0.2	-0.7	-0.8	1.0	-1.3	-0.7
Pulse rate	0.4	0.6	2.6	1.6	1.0	0.7	1.0	1.0	0.1	0.3	-0.2	0.2	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.9	1.3	-1.1	-0.7	-1.0	-1.0	-1.7	0.5	-1.1	-0.1	-0.1
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.3	-0.8	0.9	1.2	0.9	1.0	0.6	0.5	0.4	0.4	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.5	0.4	-0.7	-0.1	-0.7	-0.6	-0.1	0.1	-0.9	1.2	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.8	-0.4	-0.3	-0.0	-0.6	-0.6	0.5	0.1	0.4	-1.7	-0.7
Diabetes diagnosed by doctor	0.4	0.6	1.2	0.5	1.1	1.0	1.1	1.1	0.7	0.7	0.1	-0.4	0.2
Guilty feelings	0.4	0.6	1.7	-1.1	-0.0	-0.4	-0.4	-0.4	-0.3	-1.3	0.3	-1.1	-0.8
Financial situation satisfaction	0.4	0.5	1.8	0.8	0.1	0.7	0.3	0.4	1.4	-1.0	0.4	0.5	0.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	-0.8	0.5	0.7	0.3	0.4	0.2	1.4	-0.7	0.5	1.0
Ever smoked	0.4	0.7	2.6	0.3	-0.0	-0.4	-0.1	-0.2	1.1	-0.2	-1.1	1.6	1.4
Risk taking	0.4	0.5	1.5	0.5	-0.8	-1.2	-0.7	-0.8	-1.1	0.4	-0.1	0.4	-0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.4	0.8	-0.3	-0.1	-0.4	-0.4	-0.3	0.8	-1.2	1.0	0.7
Age started oral contraceptive pill	0.4	0.4	1.1	-0.9	-0.3	-0.5	-0.0	-0.1	0.3	-1.1	0.9	-0.6	-0.9
Diastolic blood pressure, automated reading	0.4	1.4	2.7	-0.5	-1.6	-0.6	-1.2	-1.1	-1.1	-1.1	1.5	-1.4	-0.9
Alzheimer’s Disease (in mother)	0.3	0.3	0.7	-0.5	0.4	-0.2	0.6	0.5	-0.8	-0.3	0.6	-0.6	-0.9
Breast Cancer	0.3	0.7	1.7	-1.0	-0.6	-1.0	-1.2	-1.3	0.2	-0.5	0.0	-0.6	0.5
Height	0.3	5.0	10.8	2.9	-0.2	-3.1	-2.8	-3.3	2.5	-2.2	-0.2	1.0	0.6
Waist Hip Ratio (WHR)	0.3	1.2	2.4	-0.1	-1.5	-1.5	-1.2	-1.3	-1.0	-1.6	1.1	-0.1	0.2
Respiratory disease	0.3	0.6	1.6	-0.4	-1.2	-1.2	-1.2	-1.2	-0.2	-0.3	0.3	-0.2	-0.3
Stomach or abdominal pain in last month	0.3	0.4	1.0	-1.0	-0.8	-0.1	-0.9	-0.9	-0.1	0.6	0.0	-0.1	0.6
Number of incorrect matches in round	0.3	0.4	2.4	0.5	0.6	0.3	0.3	0.3	0.3	1.0	-1.5	-0.0	0.1
Qualifications: None of the above	0.3	0.6	2.3	-0.8	0.8	-0.1	0.3	0.2	1.5	-0.8	1.3	-0.5	-0.1
Standing height	0.3	3.4	9.8	1.3	-0.8	-3.1	-2.7	-3.0	0.3	-2.1	0.4	-0.3	-0.5
Gout (self-reported)	0.3	0.4	2.0	0.7	0.0	-0.6	-0.6	-0.7	1.4	-0.4	0.5	-0.0	-0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.9	0.4	0.7	1.0	0.3	0.4	1.4	0.9	0.5	-0.2	0.4
Age at first live birth	0.3	0.5	1.8	0.0	-0.8	-1.4	-0.7	-0.9	-0.4	-0.6	0.2	0.6	-0.5
Health satisfaction	0.3	0.4	1.7	-0.5	0.3	0.2	1.3	1.2	-0.5	0.2	0.2	0.3	-0.2
Angina (self-reported)	0.3	0.4	1.2	-0.7	-0.2	0.6	0.3	0.4	-0.1	-1.1	1.0	-0.3	-0.2
Age at last live birth	0.3	0.5	1.6	0.0	-0.7	-1.2	-0.5	-0.6	0.4	-1.3	0.6	0.4	-0.4
Illnesses of father: Heart disease	0.3	0.5	1.2	-0.4	0.2	1.0	1.0	1.1	-0.5	-0.9	0.5	0.3	0.2
Loneliness, isolation	0.3	0.5	1.5	-0.7	-0.4	-0.2	-0.5	-0.5	-0.3	0.4	-1.0	0.8	1.2
Illnesses of father: None of the above (group 1)	0.3	0.3	1.6	0.4	-0.0	0.1	-0.6	-0.5	1.3	-0.2	-0.5	0.4	0.5
Average weekly champagne plus white wine intake	0.3	0.4	1.5	1.2	0.3	-0.4	0.1	-0.1	1.0	0.6	-0.7	0.3	0.2
Hearing aid user	0.3	0.4	0.9	-0.5	0.6	0.7	0.5	0.6	1.0	-0.7	0.7	-0.1	-0.0
Commuting to job workplace: Public transport	0.3	0.4	1.4	-0.6	-0.8	-0.2	-0.8	-0.7	-1.2	-0.4	-0.2	0.0	-0.5
Unable to work because of sickness or disability	0.3	0.5	1.2	-1.1	-0.6	-1.0	-0.5	-0.6	-0.1	-0.6	0.6	-0.6	-0.5
Heart disease (siblings)	0.3	0.4	1.5	0.3	-0.6	-1.2	-0.5	-0.6	0.4	0.9	0.6	-0.4	-0.2
Reaction Time	0.2	0.4	1.4	1.0	-0.4	-0.2	-0.1	-0.1	0.6	0.6	-0.7	1.2	0.7
Ovarian Cancer	0.2	0.3	2.3	-0.3	-0.2	0.2	0.0	0.1	-0.4	1.5	-0.1	-0.1	0.1
Blood Eosinophil Count	0.2	1.6	3.2	1.8	0.9	0.7	0.2	0.3	1.7	0.4	-1.8	1.4	1.6
Heel T-Score	0.2	1.9	6.2	0.8	-2.5	-0.9	-1.9	-1.9	0.5	-0.6	-1.3	0.9	1.1
Smoking Status	0.2	0.4	1.3	-0.6	-0.1	0.6	0.4	0.5	0.7	-0.1	-0.6	0.7	1.1
Hypothyroidism (self reported)	0.2	0.4	1.6	1.0	0.3	0.4	0.1	0.1	0.7	1.2	0.4	0.1	0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.0	-0.5	0.9	0.6	1.0	1.0	0.4	0.7	0.1	-0.4	-0.0
Tanning	0.2	2.6	8.5	-1.7	0.3	-0.9	0.2	-0.0	-0.9	-0.8	2.9	-2.6	-2.3
Hand grip strength (left)	0.2	0.5	2.8	0.1	0.7	-1.7	0.1	-0.2	-0.1	0.7	-0.2	-0.0	-0.8
Angina	0.2	0.3	0.8	-0.6	-0.5	0.5	0.0	0.2	-0.2	-0.9	0.8	-0.3	0.0
Townsend deprivation index at recruitment	0.2	0.3	1.2	0.5	-0.6	-0.4	-0.6	-0.6	0.3	-0.3	-0.2	0.6	1.1
Qualifications: CSEs or equivalent	0.2	0.3	0.7	0.8	0.7	0.2	0.6	0.6	0.3	-0.2	0.8	-0.4	-0.3
Past tobacco smoking	0.2	0.3	1.1	0.8	-0.1	0.6	-0.2	-0.0	-0.6	1.0	-0.1	-0.7	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	-0.7	-0.2	-0.9	-0.4	-0.5	-0.5	0.7	-0.1	-0.3	0.1
Medication: Ramipril	0.2	0.2	0.4	-0.4	0.5	0.6	0.6	0.6	0.5	-0.4	0.6	-0.5	-0.0
Falls in the last year	0.2	0.3	0.7	-0.1	-0.6	-0.1	-0.6	-0.5	-0.4	-0.7	-0.3	0.6	0.8
Asthma	0.2	0.4	0.8	0.1	0.6	0.5	0.7	0.7	0.9	-0.5	0.7	-0.3	-0.6
Prospective memory result	0.2	0.3	1.5	0.1	0.5	0.4	0.7	0.6	1.2	-0.2	-0.3	-0.4	-0.3
Medication: Paracetamol	0.2	0.3	0.8	0.5	-0.9	-0.3	-0.8	-0.7	-0.2	-0.4	0.3	0.3	0.5
Worry too long after embarrassment	0.2	0.4	0.9	0.6	-0.4	0.1	-0.7	-0.6	0.5	-0.1	-0.9	0.6	1.0
Wheeze or whistling in the chest in last year	0.2	0.4	1.4	-0.6	-0.6	-1.2	-0.8	-0.9	-0.5	0.6	-0.0	-0.1	0.3
Alcohol intake frequency.	0.2	0.5	1.4	0.6	0.5	1.0	0.7	0.8	1.2	0.8	-0.4	0.4	0.4
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.2	-0.2	0.7	-0.1	-0.0	0.4	-0.4	-0.5	0.8	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.9	-1.0	-0.4	0.3	0.2	0.2	0.7	-0.2	0.6	-0.2	0.4
Asthma (self-reported)	0.2	0.3	0.6	0.0	0.5	0.2	0.6	0.6	0.7	-0.8	0.8	-0.5	-0.7
Bipolar Disorder or Schizophrenia	0.1	0.2	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	1.3
Fasting Glucose	0.1	0.1	0.7	0.0	0.8	0.0	0.0	0.0	-0.2	0.5	0.0	0.0	0.0
Blood White Count	0.1	0.7	3.1	-1.6	-0.4	-0.7	0.1	0.0	-1.8	0.4	0.3	-0.6	0.0
Neuroticism	0.1	0.2	1.6	-1.3	0.2	0.1	0.1	0.0	-0.7	0.1	-0.4	-0.4	-0.2
Number of treatments/medications taken	0.1	0.2	0.6	-0.6	-0.3	0.4	-0.0	0.1	-0.2	0.4	0.8	-0.7	-0.3
Relative age of first facial hair	0.1	0.2	1.1	-0.1	0.1	0.5	0.1	0.2	-0.2	-0.2	-1.0	0.7	0.5
Taking other prescription medications	0.1	0.2	0.7	-0.5	0.2	0.8	0.1	0.2	0.5	-0.1	0.0	0.4	0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.5	-0.1	-0.2	0.1	0.0	0.1	0.6	-0.3	0.3	0.2
Diabetes (self-reported)	0.1	0.1	0.7	-0.1	0.1	0.2	0.0	0.0	-0.1	0.1	0.5	-0.8	-0.1
Number of live births	0.1	0.2	0.5	-0.2	0.4	-0.5	0.4	0.2	0.3	0.1	0.5	-0.4	-0.7
Birth weight	0.1	0.2	0.7	0.4	-0.1	-0.4	-0.1	-0.2	-0.3	0.3	-0.6	-0.8	-0.5
Eye problems/disorders: None of the above	0.1	0.2	0.6	0.6	-0.1	-0.7	-0.4	-0.4	-0.3	0.6	0.2	0.1	-0.0
Mean time to correctly identify matches	0.1	0.2	0.9	0.3	0.1	-0.2	0.1	0.0	0.6	1.0	-0.3	0.8	0.4
Comparative height size at age 10	0.1	0.8	2.4	0.3	1.5	-0.4	0.6	0.3	1.5	-0.1	0.8	-1.0	-0.7
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.6	0.5	-0.1	0.5	0.3	0.3	0.4	0.0	0.1	0.3	0.8
Smoking status: Previous	0.1	0.2	0.7	-0.8	0.1	-0.3	0.2	0.2	0.5	-0.7	0.2	0.7	0.3
Supplements: Calcium	0.1	0.2	1.0	-0.3	0.2	0.2	0.1	0.1	1.0	-0.6	-0.1	0.0	0.1
Bipolar Disorder (2018)	0.0	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	-0.1	0.0	0.0	0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	-0.2	0.0	0.0	0.9
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.7	2.6	-0.7	-0.3	1.4	-0.3	0.0	1.6	-0.8	0.0	0.3	1.2
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.2	0.1	-0.2	0.5	-0.0	0.0	-0.5	-0.1	-0.2	0.1	0.3

Hub : Genes

SLC35E2

Models

Trait associations