Best TWAS P=9.11e-12 · Best GWAS P=5.75e-10 conditioned to 0.000348
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | ZFP36L2 | 0.06 | 0.00 | lasso | 8 | 0.01 | 3.5e-02 | 5.0 | -5.5 | 3.7e-08 | 0.22 | 0.11 | 0.58 | FALSE |
| 2 | GTEx | Thyroid | AC010883.5 | 0.11 | 0.09 | lasso | 2 | 0.08 | 1.5e-06 | 6.1 | 6.1 | 1.0e-09 | -0.24 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Vagina | ZFP36L2 | 0.32 | 0.08 | enet | 27 | 0.14 | 4.7e-04 | 4.6 | -5.6 | 2.6e-08 | 0.48 | 0.06 | 0.37 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP36L2 | 0.03 | 0.01 | blup | 38 | 0.01 | 1.1e-02 | 6.2 | -6.8 | 9.1e-12 | 0.44 | 0.01 | 0.82 | TRUE |