Best TWAS P=1.53e-17 · Best GWAS P=2.16e-14 conditioned to 0.0978
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AC005104.3 | 0.10 | 0.01 | lasso | 4 | 0.01 | 1.6e-01 | -4.9 | 5.4 | 6.0e-08 | 0.08 | 0.01 | 0.80 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Female) | GPR35 | 0.27 | 0.02 | enet | 17 | 0.08 | 2.6e-03 | 7.6 | 5.4 | 5.7e-08 | 0.60 | 0.01 | 0.74 | FALSE |
| 3 | GTEx | Nerve Tibial | CAPN10 | 0.25 | 0.07 | lasso | 10 | 0.13 | 3.1e-09 | -6.1 | -5.4 | 7.2e-08 | -0.27 | 0.97 | 0.01 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GPR35 | 0.05 | 0.01 | blup | 66 | 0.03 | 3.9e-04 | 7.6 | 8.5 | 1.5e-17 | 0.71 | 0.00 | 0.94 | TRUE |