[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr2:233,227,833-234,904,144

Best TWAS P=2.21e-28 · Best GWAS P=5.41e-29 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATG16L1	0.06	0.03	bslmm	587	0.03	3.3e-04	-2.780	7.4	1.9e-13	-0.62	0.06	0.90	FALSE
2	GTEx	Adipose Subcutaneous	ATG16L1	0.14	0.11	lasso	4	0.10	6.4e-09	-10.600	-10.6	4.5e-26	0.97	0.02	0.98	FALSE
3	GTEx	Brain Caudate basal ganglia	ATG16L1	0.21	0.09	lasso	2	0.10	6.8e-04	-8.560	-8.1	6.2e-16	0.76	0.10	0.58	FALSE
4	GTEx	Brain Cerebellum	ATG16L1	0.23	0.27	lasso	4	0.30	2.0e-09	-11.000	-11.0	2.2e-28	0.99	0.02	0.98	TRUE
5	GTEx	Esophagus Mucosa	ATG16L1	0.11	0.02	enet	10	0.00	2.3e-01	-11.100	10.3	5.4e-25	-0.88	0.02	0.90	FALSE
6	GTEx	Esophagus Muscularis	ATG16L1	0.11	0.03	lasso	6	0.02	2.7e-02	-9.310	-10.4	2.2e-25	0.96	0.02	0.97	FALSE
7	GTEx	Nerve Tibial	ATG16L1	0.24	0.18	enet	21	0.19	3.5e-13	-10.600	-9.5	1.6e-21	0.91	0.04	0.96	FALSE
8	GTEx	Pituitary	ATG16L1	0.36	0.16	lasso	8	0.19	1.3e-05	-6.850	-7.2	7.2e-13	0.72	0.06	0.88	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	ATG16L1	0.12	0.10	enet	11	0.11	1.7e-06	-11.100	10.8	3.5e-27	-0.99	0.02	0.98	FALSE
10	GTEx	Skin Sun Exposed Lower leg	ATG16L1	0.21	0.08	enet	18	0.10	5.6e-09	-11.000	9.0	1.9e-19	-0.91	0.01	0.99	FALSE
11	GTEx	Testis	ATG16L1	0.34	0.19	enet	29	0.23	1.4e-10	-11.000	9.7	2.6e-22	-0.88	0.02	0.98	FALSE
12	METSIM	Adipose	INPP5D	0.05	0.01	lasso	4	0.03	6.2e-06	-0.068	-5.4	6.3e-08	0.56	0.02	0.96	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	ATG16L1	0.28	0.26	lasso	9	0.28	3.3e-36	-4.890	-7.3	3.0e-13	0.79	1.00	0.00	FALSE
14	YFS	Blood	ATG16L1	0.21	0.28	lasso	7	0.30	2.2e-99	-4.850	6.6	3.5e-11	-0.73	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ATG16L1	0.05	0.04	enet	12	0.05	5.4e-06	-8.750	10.0	2.3e-23	-0.82	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATG16L1	0.22	0.06	enet	36	0.10	6.2e-12	-10.600	-7.7	1.7e-14	0.70	0.03	0.97	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ATG16L1	0.11	0.05	blup	81	0.09	1.9e-04	-10.600	-9.8	9.0e-23	0.93	0.02	0.86	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	ATG16L1	0.07	0.04	lasso	4	0.03	3.6e-03	-6.760	6.7	1.6e-11	-0.74	0.03	0.18	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	SCARNA5	0.04	0.00	blup	55	0.02	8.2e-03	-9.310	-8.5	2.5e-17	0.74	0.02	0.50	FALSE