Best TWAS P=1.76e-14 · Best GWAS P=3.85e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF638 | 0.06 | 0.01 | bslmm | 559 | 0.02 | 1.8e-03 | -7.4 | -6.0 | 2.4e-09 | 0.68 | 0.02 | 0.95 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | ZNF638 | 0.09 | 0.02 | lasso | 3 | 0.01 | 2.9e-02 | -5.5 | -5.5 | 3.4e-08 | 0.35 | 0.13 | 0.62 | FALSE |
| 3 | GTEx | Artery Aorta | ZNF638 | 0.25 | 0.07 | enet | 20 | 0.10 | 5.2e-06 | -7.3 | -7.7 | 1.8e-14 | 0.97 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Artery Tibial | ZNF638 | 0.10 | 0.06 | enet | 13 | 0.07 | 2.4e-06 | -7.3 | -7.2 | 5.7e-13 | 0.86 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF638 | 0.08 | 0.05 | enet | 10 | 0.05 | 5.6e-06 | -7.4 | -5.8 | 5.0e-09 | 0.86 | 0.01 | 0.99 | FALSE |