Best TWAS P=3.08e-08 · Best GWAS P=1.59e-06 conditioned to 0.25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DHFRL1 | 0.07 | 0.05 | enet | 17 | 0.05 | 2.5e-06 | -4.7 | 5.2 | 2.6e-07 | -0.84 | 0 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | STX19 | 0.51 | 0.13 | enet | 19 | 0.34 | 3.9e-40 | -3.5 | -5.1 | 2.9e-07 | 0.97 | 0 | 0.36 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | STX19 | 0.28 | -0.01 | enet | 15 | 0.08 | 6.4e-04 | -3.5 | -5.5 | 3.1e-08 | 0.94 | 0 | 0.00 | TRUE |