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chr4:151,347,355-153,373,680

Best TWAS P=6.92e-13 · Best GWAS P=8.93e-13 conditioned to 0.0812

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM160A1	0.04	0.04	blup	436	0.06	1.8e-07	-7.1	7.2	6.9e-13	-0.88	0.03	0.97	TRUE
2	CommonMind	Brain Pre-frontal Cortex	PET112	0.16	0.24	lasso	10	0.23	2.7e-27	-5.7	5.8	8.8e-09	-0.78	0.99	0.01	FALSE
3	GTEx	Adipose Subcutaneous	PET112	0.21	0.16	lasso	8	0.15	5.4e-12	-5.7	5.8	8.2e-09	-0.78	0.99	0.01	FALSE
4	GTEx	Artery Aorta	PET112	0.17	0.10	lasso	9	0.11	1.2e-06	-5.5	6.0	2.5e-09	-0.78	0.95	0.04	FALSE
5	GTEx	Artery Coronary	PET112	0.16	0.13	lasso	11	0.14	1.7e-05	-5.9	5.9	3.3e-09	-0.79	0.45	0.28	FALSE
6	GTEx	Artery Tibial	PET112	0.17	0.14	lasso	3	0.13	4.3e-10	-5.9	5.9	4.7e-09	-0.79	0.99	0.01	FALSE
7	GTEx	Brain Caudate basal ganglia	PET112	0.13	0.15	lasso	3	0.12	2.7e-04	-5.9	5.9	4.3e-09	-0.80	0.19	0.41	FALSE
8	GTEx	Brain Cerebellar Hemisphere	PET112	0.24	0.24	lasso	6	0.21	4.6e-06	-5.6	5.8	5.8e-09	-0.76	0.24	0.64	FALSE
9	GTEx	Brain Cerebellar Hemisphere	SH3D19	0.28	0.22	lasso	5	0.20	9.3e-06	4.9	-5.3	1.2e-07	0.79	0.71	0.03	FALSE
10	GTEx	Brain Cerebellum	PET112	0.13	0.15	lasso	8	0.13	1.3e-04	-6.1	6.1	1.3e-09	-0.81	0.19	0.42	FALSE
11	GTEx	Brain Cerebellum	RP11-164P12.3	0.21	0.02	enet	19	0.03	3.4e-02	5.1	5.8	7.2e-09	-0.75	0.23	0.16	FALSE
12	GTEx	Brain Cerebellum	RP11-164P12.4	0.48	0.40	lasso	17	0.49	2.2e-16	-6.5	6.0	1.7e-09	-0.87	0.88	0.11	FALSE
13	GTEx	Brain Cortex	PET112	0.11	0.13	enet	22	0.12	4.1e-04	-6.0	5.9	4.2e-09	-0.84	0.13	0.72	FALSE
14	GTEx	Brain Frontal Cortex BA9	PET112	0.22	0.13	enet	14	0.05	1.6e-02	-7.1	5.5	4.9e-08	-0.87	0.03	0.86	FALSE
15	GTEx	Breast Mammary Tissue	PET112	0.12	0.03	enet	11	0.01	1.4e-01	-4.3	5.5	3.7e-08	-0.77	0.25	0.64	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	PET112	0.26	0.20	enet	23	0.26	3.7e-09	-7.0	-5.1	3.1e-07	0.86	0.02	0.98	FALSE
17	GTEx	Colon Sigmoid	PET112	0.13	0.08	enet	18	0.03	2.6e-02	-5.7	5.4	5.0e-08	-0.81	0.11	0.76	FALSE
18	GTEx	Esophagus Mucosa	PET112	0.07	0.10	lasso	1	0.09	1.8e-06	-5.7	5.7	1.5e-08	-0.77	0.45	0.52	FALSE
19	GTEx	Esophagus Muscularis	PET112	0.13	0.12	lasso	1	0.13	3.9e-08	-5.6	5.6	1.7e-08	-0.77	0.95	0.02	FALSE
20	GTEx	Heart Atrial Appendage	PET112	0.20	0.11	enet	24	0.18	2.1e-08	-6.4	6.0	1.6e-09	-0.81	0.09	0.90	FALSE
21	GTEx	Heart Atrial Appendage	RP11-164P12.3	0.13	0.03	lasso	5	0.02	4.4e-02	-5.3	6.6	4.5e-11	-0.80	0.20	0.29	FALSE
22	GTEx	Heart Left Ventricle	PET112	0.14	0.06	lasso	4	0.04	5.0e-03	-7.1	7.1	1.3e-12	-0.99	0.03	0.90	FALSE
23	GTEx	Muscle Skeletal	PET112	0.10	0.07	lasso	5	0.07	3.6e-07	-5.7	5.7	9.7e-09	-0.78	0.91	0.08	FALSE
24	GTEx	Nerve Tibial	PET112	0.13	0.10	enet	13	0.10	9.7e-08	-6.7	6.7	1.7e-11	-0.93	0.04	0.96	FALSE
25	GTEx	Nerve Tibial	RP11-164P12.3	0.08	0.14	lasso	6	0.14	8.3e-10	-6.0	6.6	5.2e-11	-0.90	0.06	0.94	FALSE
26	ROSMAP	Brain Pre-frontal Cortex	PET112	0.04	0.02	bslmm	410	0.04	5.2e-06	-7.1	6.1	8.4e-10	-0.81	0.02	0.97	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	PET112L	0.05	0.02	enet	6	0.03	4.0e-04	-6.1	5.5	3.6e-08	-0.79	0.07	0.87	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	PET112L	0.02	0.01	lasso	1	0.01	7.1e-02	-5.9	5.9	4.6e-09	-0.80	0.07	0.26	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FAM160A1	0.07	0.03	lasso	3	0.05	1.9e-04	-3.7	5.4	6.7e-08	-0.66	0.44	0.18	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FAM160A1	0.08	0.05	blup	99	0.05	2.9e-03	-5.3	5.1	3.1e-07	-0.71	0.11	0.22	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PET112L	0.09	0.04	blup	76	0.07	1.0e-03	-5.7	6.3	2.6e-10	-0.84	0.12	0.64	FALSE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PET112L	0.09	0.07	lasso	2	0.06	2.5e-03	-6.1	6.2	5.7e-10	-0.80	0.08	0.29	FALSE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	FAM160A1	0.09	0.10	lasso	2	0.10	3.3e-10	5.6	5.6	2.4e-08	-0.81	0.96	0.04	FALSE
34	The Cancer Genome Atlas	Stomach Adenocarcinoma	PET112L	0.04	0.03	blup	77	0.02	6.6e-03	-4.8	5.1	2.9e-07	-0.63	0.10	0.14	FALSE
35	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	FAM160A1	0.16	0.14	enet	33	0.11	6.6e-04	4.9	5.3	1.1e-07	-0.75	0.24	0.69	FALSE