Best TWAS P=1.22e-09 · Best GWAS P=5.3e-10 conditioned to 0.0491
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | TMEM170B | 0.20 | 0.10 | lasso | 3 | 0.09 | 2.8e-05 | 5.2 | -5.2 | 1.9e-07 | -0.78 | 0.07 | 0.93 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | TMEM170B | 0.21 | 0.14 | lasso | 10 | 0.12 | 1.4e-09 | 6.0 | -6.1 | 1.2e-09 | -0.85 | 0.02 | 0.98 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | TMEM170B | 0.16 | 0.10 | lasso | 4 | 0.10 | 2.4e-06 | 6.2 | -5.8 | 5.3e-09 | -0.86 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TMEM170B | 0.19 | 0.19 | lasso | 6 | 0.20 | 2.1e-16 | 5.2 | -5.2 | 1.5e-07 | -0.78 | 0.77 | 0.23 | FALSE |
| 5 | METSIM | Adipose | TMEM170B | 0.21 | 0.30 | lasso | 2 | 0.30 | 6.8e-45 | 5.2 | -5.2 | 1.9e-07 | -0.78 | 0.75 | 0.25 | FALSE |