Best TWAS P=3.59e-11 · Best GWAS P=3.25e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | DBN1 | 0.11 | 0.13 | enet | 11 | 0.13 | 8.4e-41 | 6.3 | 6.6 | 3.6e-11 | -0.96 | 0.05 | 0.95 | TRUE |
| 2 | YFS | Blood | GRK6 | 0.18 | 0.21 | lasso | 4 | 0.21 | 5.4e-68 | 6.4 | 6.4 | 2.0e-10 | -0.94 | 0.05 | 0.95 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PRR7 | 0.07 | 0.04 | lasso | 3 | 0.05 | 2.2e-06 | -6.6 | 5.5 | 3.9e-08 | -0.86 | 0.01 | 0.98 | FALSE |