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chr8:65,740,418-67,245,848

Best TWAS P=1.09e-08 · Best GWAS P=8.09e-08 conditioned to 0.00957

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC286186	0.29	0.31	enet	36	0.41	1.4e-53	-5.3	5.2	2.1e-07	0.65	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	CTD-3025N20.3	0.18	0.26	enet	12	0.26	2.4e-21	-5.0	5.2	2.0e-07	0.57	0.03	0.96	FALSE
3	GTEx	Adrenal Gland	CTD-3025N20.3	0.16	0.12	lasso	7	0.12	6.6e-05	-5.0	5.4	7.0e-08	0.58	0.03	0.97	FALSE
4	GTEx	Artery Coronary	CTD-3025N20.3	0.36	0.30	lasso	5	0.32	1.2e-11	-5.0	5.1	2.7e-07	0.54	0.04	0.96	FALSE
5	GTEx	Artery Tibial	CTD-3025N20.3	0.24	0.28	lasso	6	0.26	1.4e-20	-5.0	5.2	2.2e-07	0.56	0.04	0.96	FALSE
6	GTEx	Brain Caudate basal ganglia	CTD-3025N20.3	0.28	0.24	lasso	3	0.26	3.2e-08	-5.0	5.1	2.6e-07	0.56	0.04	0.96	FALSE
7	GTEx	Brain Cerebellar Hemisphere	CTD-3025N20.3	0.34	0.32	enet	27	0.40	1.6e-11	-5.0	5.4	8.0e-08	0.64	0.04	0.96	FALSE
8	GTEx	Brain Cerebellum	CTD-3025N20.3	0.34	0.39	enet	19	0.34	7.4e-11	-5.0	5.2	2.5e-07	0.69	0.04	0.96	FALSE
9	GTEx	Brain Hippocampus	CTD-3025N20.3	0.20	0.15	lasso	6	0.10	2.1e-03	-4.9	5.2	2.3e-07	0.57	0.03	0.84	FALSE
10	GTEx	Brain Hypothalamus	CTD-3025N20.3	0.34	0.35	lasso	5	0.32	2.2e-08	-5.0	5.2	2.0e-07	0.54	0.04	0.96	FALSE
11	GTEx	Breast Mammary Tissue	CTD-3025N20.3	0.24	0.26	lasso	9	0.26	8.5e-14	-5.0	5.3	1.3e-07	0.60	0.04	0.96	FALSE
12	GTEx	Breast Mammary Tissue (Female)	CTD-3025N20.3	0.27	0.22	lasso	7	0.21	6.9e-07	-5.0	5.4	6.6e-08	0.62	0.04	0.96	FALSE
13	GTEx	Esophagus Mucosa	ARMC1	0.15	0.02	enet	14	0.02	1.2e-02	-5.0	-5.6	2.1e-08	-0.34	0.04	0.87	FALSE
14	GTEx	Heart Atrial Appendage	CTD-3025N20.3	0.22	0.20	lasso	3	0.20	3.6e-09	-5.0	5.2	2.0e-07	0.59	0.04	0.96	FALSE
15	GTEx	Lung	CTD-3025N20.3	0.13	0.12	lasso	5	0.12	1.5e-09	-5.3	5.4	5.7e-08	0.60	0.02	0.98	FALSE
16	GTEx	Muscle Skeletal	CTD-3025N20.3	0.15	0.14	lasso	9	0.17	2.4e-16	-5.0	5.7	1.1e-08	0.56	0.04	0.96	TRUE
17	GTEx	Pancreas	CTD-3025N20.3	0.12	0.08	enet	12	0.07	5.7e-04	-5.0	5.3	1.0e-07	0.57	0.03	0.95	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	CTD-3025N20.3	0.28	0.28	enet	18	0.28	1.3e-15	-5.0	5.3	9.8e-08	0.57	0.04	0.96	FALSE
19	GTEx	Testis	CTD-3025N20.3	0.27	0.28	enet	21	0.31	2.6e-14	-5.0	5.6	2.3e-08	0.53	0.04	0.96	FALSE
20	METSIM	Adipose	CTD-3025N20.3	0.08	0.07	enet	18	0.08	2.8e-12	-4.2	5.2	2.5e-07	0.60	0.03	0.97	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	CTD-3025N20.2	0.36	0.35	lasso	14	0.43	4.1e-61	-5.3	5.2	2.2e-07	0.63	0.01	0.99	FALSE