Best TWAS P=2.36e-13 · Best GWAS P=3.62e-14 conditioned to 0.0203
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | RUNX1T1 | 0.07 | 0.03 | lasso | 4 | 0.00 | 0.17800 | -7.0 | -7.3 | 2.4e-13 | 0.89 | 0.10 | 0.71 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RUNX1T1 | 0.03 | 0.03 | blup | 59 | 0.02 | 0.00068 | -7.2 | 5.7 | 1.2e-08 | -0.84 | 0.02 | 0.89 | FALSE |